F. Li

This study evaluates UAV-based remote sensing for predicting nitrogen content and nitrogen agronomic efficiency in winter wheat organs using vegetation indices and texture features.

This study identifies molecular and genetic mechanisms underlying the transition from dioecy to monoecy in Diospyros oleifera using genome-wide analyses of 150 accessions.

The paper traces the evolutionary origin of brackish archaea, showing gene rearrangements enabled their adaptation to coastal environments after the Cryogenian Snowball Earth.

The paper introduces an improved algorithm for inferring mutational parameters from Bar-Seq evolution experiments, showing better performance in identifying adaptive mutations and their parameters.

The paper shows early life adversity and adult social isolation independently reduce survival in wild baboons, supporting both health selection and social causation hypotheses.

The paper determines the structure of VGLUT2 with a glutamate analog bound, revealing mechanisms of substrate recognition, electrostatic interactions, and palmitoylation's role in transporter retrieval.

The paper profiles 218 cytotoxic and nuisance compounds in U-2 OS cells to create reference compounds for improving assay optimization and compound prioritization in cellular morphology assays.

This study uses two-photon microscopy to observe astrocyte reactivity in mouse brains after intracortical microelectrode implantation, revealing distinct spatiotemporal dynamics compared to other glial cells.

This study shows that neutrophils in tuberculosis promote pathologic hematopoiesis by producing G-CSF, which impairs T-cell immunity through IFNAR1 signaling.

This study uses deep learning to predict neoadjuvant chemotherapy benefit in breast cancer using stromal histology, introducing the TS-score which outperforms existing predictors.

The paper engineers bacteria to release chemokines that recruit immune cells into tumors, enhancing anti-tumor immunity in mouse models.

This study uses GWAS to identify 277 candidate genes associated with adventitious rooting in Populus trichocarpa, highlighting roles in hormone signaling, cell division, and reactive oxygen species.

This study uses GWAS to identify candidate genes regulating in planta regeneration in Populus trichocarpa, finding over 200 genes involved in cell adhesion, stress signaling, and hormone pathways.

The paper characterizes the evolution of multidrug-resistant ST131 E. coli isolates in a chronic bone infection, identifying genomic changes linked to small colony variants and persistence.

This study shows that suppressing CMTM6 in tumors or hosts enhances anti-tumor immunity independently of PD-L1, suggesting CMTM6 as a target for gene therapy.

This study identifies Slamf9+Spp1+ macrophages in hamsters that promote SARS-CoV-2 clearance and inflammation resolution through spatial transcriptomics and scRNA-seq.

The paper identifies a tnd biosynthetic cluster in Aspergillus flavipes and characterizes a bifunctional diterpene synthase, leading to the discovery of talarodiene and its transformation into talaronoid C.

This study shows DDX4, a germline factor, enhances chemoresistance and motility in SCLC cells by altering metabolism and EMT-like features.

This paper introduces Wolffia australiana as a model system for studying plant morphogenesis using a Plant-on-Chip culture system and advanced technologies like snRNA-seq.

This paper introduces a high-throughput plant phenotyping system with a GUI and SGIOS algorithm to streamline training data generation and improve GWAS for trait variation analysis.

This study shows that an Omicron-specific subunit vaccine booster enhances neutralizing antibodies against SARS-CoV-2 variants and the ancestral virus, with a two-dose WT-RBD plus Omicron-RBD booster showing the strongest response.

The paper develops a method to rapidly quantify PHA in living cells using GFP-labeled phasins, achieving high accuracy with R-squares over 0.9.

This study identifies WDFY3 as a novel regulator of macrophage efferocytosis through a genome-wide CRISPR screen, revealing its role in actin depolymerization and lysosomal acidification.

The paper presents 52 high-quality genomes of rumen ciliates, reclassifying them into 19 species and identifying their biomass-degrading enzymes.

This study identifies VRK1 as a synthetic lethal target in VRK2-methylated glioblastoma by showing that VRK1 inhibition leads to tumor growth inhibition in xenograft models.

This study identifies PDK1 as a driver of osimertinib resistance in NSCLC, showing its inhibition sensitizes resistant cells and correlates with disease progression.

This study identifies a potent human monoclonal antibody, 35B5, that neutralizes SARS-CoV-2 and its variants by targeting a conserved epitope on the RBD, offering a potential therapeutic and vaccine design strategy.

The paper estimates beneficial mutation rates and fitness effects using simulation-based Bayesian inference on CNV dynamics in yeast.

This paper demonstrates a method for unidirectional transport of full-length proteins through nanopores using guanidinium chloride and machine learning to identify protein orientation and identity.

This study constructs a prognostic model for AML using multiomics data to identify immune-related biomarkers and classify patients into subtypes with different survival outcomes.