N. Wang

This study investigates how black soybean peptides alleviate oxidative damage caused by alpha gliadin peptide in a celiac disease cell model.

This study shows that blocking VEGF, Ang2, and PD1 reprograms GBM endothelial cells into quasi-antigen-presenting cells, enhancing anti-tumor responses and controlling edema.

This study compares root growth responses of the halophyte Schrenkiella parvula and Arabidopsis thaliana under salt stress, identifying gene regulatory differences and physiological adaptations that enable salt tolerance.

This study analyzes genomic diversity in Asian white birch to identify signals of adaptation and hybridization, finding 7,609 SNPs associated with environmental variables and highlighting climate change risks.

This paper develops high-affinity, structurally confirmed allosteric CDK2 inhibitors that show negative cooperativity with cyclin binding and demonstrate contraceptive potential in mouse testicular explants.

The paper identifies nalacin as an inhibitor of GH3 amido synthetase, which regulates auxin conjugation in plants, with potential applications in agriculture and research.

This paper identifies synthetic lethality between PRC2 inactivation and DNMT1 inhibition in MPNST, showing enhanced cytotoxicity through retrotransposon activation and innate immune signaling.

This study shows that hypereosinophilia in mice leads to cardiac inflammation and impaired cardiomyocyte contractility, contributing to heart dysfunction.

This study identifies TMEM100 as a key regulator of silent nociceptor activation during inflammation and shows its role in inducing remote pain hypersensitivity.

This study identifies sustained molecular signatures in monocytes and regulatory T cells in convalescent COVID-19 patients, associated with disease severity.

The paper evaluates five compost-based substrates for Camellia oleifera seedling cultivation, finding that a specific combination yields optimal growth and survival rates.

This paper systematically characterizes double emulsion droplets to predict their size and stability based on flow rates and buffer properties, enabling better design of bioassays.

This study identifies a conformational switch in the alpha-synuclein C-terminus domain that determines fibril polymorphs by altering morphology in response to ionic strength and temperature.

This study shows Harringtonine inhibits SARS-CoV-2 membrane fusion by targeting both the viral S protein and host TMPRSS2, effectively blocking infection in delta and Omicron variants.

The paper identifies CpGs with divergent age-related methylation patterns in long and short-lived mammals and develops epigenetic clocks based on these CpGs.

The paper characterizes structural and functional changes in the SARS-CoV-2 Omicron variant's Spike protein, identifying new immune escape sites and providing insights for vaccine development.

Antibodies from 3-dose vaccinated individuals neutralize Omicron and other variants, with some being ultrapotent and broadly reactive.

The paper identifies STAT2 as a regulator of PD-L1 expression through multi-omics analysis and experimental validation, linking it to tumor immune evasion.

This paper identifies NTD-targeting neutralizing antibodies and shows that combining RBD and NTD antibodies reduces the emergence of neutralization-escape mutants.

This paper improves a CRISPR/Cas9 system for sweet orange to generate biallelic mutations with high efficiency, enabling the creation of canker-resistant citrus varieties.

This paper adapts base editors for precise gene editing in citrus, achieving transgene-free resistance to pathogens and herbicides.

This study investigates how grafting affects anthocyanin synthesis in grapevines by analyzing metabolomic and transcriptomic profiles across different grafting conditions.

This study shows that exosomal miR-140-3p from diabetic BMSCs promotes bone restoration in diabetic rats by enhancing osteogenesis and inhibiting the plexin B1 signaling pathway.

This paper introduces a chemogenetic switch for CAR-T cells using HCV-NS3 protease, enabling controlled activation through ASV concentration modulation.

This study shows citrus Huanglongbing is an immune-mediated disease caused by CLas, where ROS-induced cell death in phloem tissues can be mitigated by antioxidants and gibberellin, reducing disease symptoms.

The paper reports the discovery of a neutralizing nanobody, VHH60, effective against SARS-CoV-2 and its variants, with high potency and protective efficacy in mice.

The paper identifies natural interploidy hybridization among wild chrysanthemum species involved in the origin of cultivated chrysanthemums, revealing patterns influenced by reproductive isolation and human activity.

The paper determines the cryo-EM structure of the chloroplast ClpP complex and shows how the co-chaperonin inhibits its proteolytic activity.

This study uses edge-based analysis to examine phylogenomic conflicts in avian evolution, revealing gene-specific biases and data type effects that impact resolution of contentious nodes.