S. Liu

This study presents haplotype-resolved genomes of triploid bananas, revealing subgenome asymmetric evolution and resistance mechanisms against banana wilt.

This study uses single-cell transcriptomics in Drosophila to show glial cells integrate circadian and homeostatic processes to regulate sleep-wake cycles.

This study shows K8.1 is critical for KSHV infection in epithelial cells but not in B cells, functioning at the attachment step.

This study characterizes the catalytic and non-catalytic mechanisms of SUV420H1 by determining cryo-EM structures and showing its role in DNA accessibility and chromatin condensation.

This study shows that IgA BCR signaling enhances B cell fitness and promotes diverse IgA responses to gut commensals by rescuing low-affinity B cells and redirecting plasma cell homing.

This study shows DHA inhibits glioma migration and invasion by upregulating ecDNA-BASP1, which suppresses EMT.

This study profiles the Mtb transcriptome using SEnd-seq and finds that incomplete transcripts dominate due to low transcription processivity and transcription-translation coupling.

The paper identifies long-B prokaryotic Argonaute systems as cell suicide mechanisms that use effector proteins to eliminate invading nucleic acids through abortive infection.

The paper uses multi-omics single-cell data to define the epigenetic basis of castration-resistant prostate luminal cells in mice and identifies key molecular pathways involved.

This study identifies PIF4 as a key regulator of water use efficiency under fluctuating light and drought in rice by modulating SAL1 and NHX1 gene expression.

This paper demonstrates wireless electrical-molecular quantum signalling using bio-nanoantennae to induce apoptosis in cancer cells through quantum biological tunnelling.

A vaccine candidate with polyprotein antigens displayed on nanocages induces neutralizing antibodies to multiple SARS-like coronaviruses.

This study introduces a deep eutectic solvent fixation method that preserves in vivo cellular states and phospho-signaling for scRNA-seq, enabling the identification of hyperactivated Th17 T cells.

This study shows that extracellular vesicles from obese women's breast adipose tissue promote mitochondrial metabolism and proliferation in ER+ breast cancer cells.

This study shows FTO stabilizes LINK-A, promoting ESCC progression through MCM3-mediated cell cycle progression and HIF-1α activation.

This study investigates how maize thermoregulates by dissipating heat from photosynthesis, showing that non-photochemical quenching (NPQ) helps maintain optimal leaf temperatures under suboptimal conditions.

The paper defines novel osteolineage gene sets using single-cell transcriptomics and identifies molecular defects in a CKD mouse model.

This study shows androgen promotes aortic aneurysms in male mice by suppressing PD-1 in T cells, suggesting immune checkpoint therapy risks for patients with aortic aneurysm risk factors.

This paper reports the structural model of the Rec114-Mei4 trimer interface and its DNA bridging activity, showing its role in meiotic DSB formation.

This study reveals that AcrIIC5 mimics dsDNA to inhibit type II-C Cas9 by blocking PAM recognition, providing insights into its mechanism and evolutionary convergence.

The paper identifies the T813S mutation in the S2 subunit of SARS-CoV Spike protein enhances fusogenicity by improving TMPRSS2 cleavage, increasing viral replication.

This study identifies Calponin 2's role in kidney fibrosis by linking cellular mechanics to metabolic reprogramming via fatty acid oxidation regulation.

The paper investigates drug resistance in Klebsiella pneumoniae, finding that rcsB regulates capsule formation, which affects drug resistance.

The paper examines seasonal and daily patterns of dissolved metabolites in the northwestern Sargasso Sea, revealing depth- and time-dependent variations and seasonal trends in key compounds.

This study determines the cryo-EM structure of human CaV2.3 channels and identifies key residues and interactions involved in channel gating and inactivation.

The paper identifies a new CRISPR-Cas12l system from metagenomes, showing it cleaves DNA with a unique PAM and forms a bracelet structure for gene editing.

This study identifies SPNS1 as a lysosomal transporter critical for exporting lysosphingolipids and lysoglycerophospholipids, linking its deficiency to lysosomal storage disease-like pathology.

This study reveals the structural basis of BIRC6's role in balancing apoptosis and autophagy by showing its dimeric structure and interactions with Smac/DIABLO, caspase 3, HtrA2, and LC3.

The paper sequenced waterbuck genomes to study speciation, finding historical gene flow across a Rift Valley barrier and no reproductive isolation.