X. Liu

This study identifies MYPT1 O-GlcNAcylation as a regulator of centrosome disjunction during mitosis, showing that it modulates Plk1 activity and affects cell cycle progression.

This study shows that Klf5 downregulation in VSMCs leads to mitochondrial fission and senescence by reducing eIF5a, which preserves mitochondrial integrity.

The paper introduces a dual nanopore technique called 'flossing' to improve DNA mapping by reducing molecular noise through repeated scans and increasing linearization efficiency.

The paper investigates how MreC and MreD regulate the interaction between PBP2 and RodA in the elongasome, showing that MreC modulates this interaction while MreD suppresses it, suggesting a mechanism for controlling elongasome activity.

The paper identifies a genomic region Lyb-2-4 associated with hypervirulence in carbapenem-resistant Acinetobacter baumannii, showing higher mortality in infected patients and mice.

This study uses rOMT to analyze glymphatic transport, showing faster solute speed in CSF and regional differences in brain parenchyma, with implications for neurodegenerative diseases.

This study analyzes the vagino-cervical microbiome of 516 women using metagenomic shotgun sequencing to explore how pregnancy, delivery, and contraception influence microbiome composition.

RhizoVision Crown is an open-source platform for high-throughput root crown phenotyping in crops, validated with simulated images and used on soybean and wheat, showing species-specific heritability.

The paper uses QTL mapping to show MHC variants bias TRBV gene usage in UCB samples, revealing germline-encoded TCR-MHC contacts influence TCR repertoire.

This paper demonstrates PhyloNet's functionalities for analyzing phylogenetic networks using simulated data and provides recommendations for data analysis and interpretation.

PIRD is a database that collects and stores annotated TCR and BCR sequencing data, along with tools for visualization and analysis.

The paper identifies JMJD6 as a protease that cleaves MePCE, releasing P-TEFb from the 7SK snRNP complex to enable Pol II-CTD phosphorylation.

This study shows that the Gly129 residue in FMDV-VP3 enhances viral pathogenicity by promoting apoptosis and autophagy through p53 interaction, and this residue is conserved across picornaviruses.

This study characterizes the structural and biochemical interactions of the MazEF-mt9 TA system in M. tb, revealing its cognate and heterologous antitoxin binding and its role in stress adaptation.

This study uses RNA-seq to analyze Xanthomonas oryzae pv. oryzicola's response to H2O2, revealing horizontal gene transfer's role in its oxidative stress response.

This study models the transmembrane potential distribution of cells under nanosecond pulsed electric fields by incorporating dielectric relaxation and electroporation effects.

This paper demonstrates that mutant KRAS-driven macropinocytosis can be exploited to deliver albumin nanoparticles into cancer cells, showing increased uptake compared to wild-type KRAS cells.

This study shows glycogen metabolism via the oxidative pentose phosphate pathway (OPPP) initiates photosynthesis in cyanobacteria by modulating NADPH levels during dark-light transitions.

The paper reports the crystal structure and cryo-EM reconstruction of a constitutively active Drosophila Orai mutant, revealing the molecular mechanism of channel activation and Ca2+ permeation.

The paper investigates how chitin triggers distinct immune signaling at the plasmodesmal plasma membrane in plants, revealing specific receptor dynamics and signaling pathways.

This paper introduces a scalable method for inferring phylogenetic networks from multi-locus data, achieving accurate results at a larger scale than existing methods.

This study identifies four key anatomical and functional differences between neonatal and adult mouse extrahepatic bile ducts that may explain their susceptibility to injury.

This study introduces SLHC-seq, a new targeted sequencing method that improves detection of pancreatic cancer by analyzing short mutant cfDNA fragments, enabling earlier diagnosis.

This study investigates the causes of increased cold-stunned Kemp's ridley turtle strandings on Cape Cod using ocean models and observations.

This study investigates the trade-off between immunity and reproduction in locusts by analyzing transcriptome changes in response to bacterial infection.

The paper identifies a peptide coating that enhances nanoparticle diffusion through the tumor microenvironment by screening phage libraries and testing transport in vitro and ex vivo.

This study combines Azospirillum brasilense inoculation with seed priming to enhance germination and seedling growth in aged grass seeds, finding that H2O2 priming with optimal bacterial concentration and time is most effective.

This study shows that actin clearance is required for dynein accumulation at the immunological synapse, which drives centrosome reorientation in T cells.

This study shows antigen receptor engagement controls methionine cycle flux and methyl donor availability for RNA and histone methylation in T cells.