X. Sun

This study analyzes the genome and multi-omics data of a C4 plant to uncover evolutionary mechanisms behind C4 photosynthesis development.

The paper identifies a SHR-IDD-PIN regulatory network that controls minor vein differentiation in rice and C4 grasses by regulating auxin flow through PIN protein expression.

The paper develops a single-cell MRD assay that detects residual leukemic clones with high sensitivity and reveals clonal architecture in AML.

This study investigates how black soybean peptides alleviate oxidative damage caused by alpha gliadin peptide in a celiac disease cell model.

This study uses ancient DNA to trace tiger evolution, revealing China as a genetic melting pot and resolving taxonomic disputes among tiger subspecies.

This paper identifies a 4-bp deletion in the maize ZmSOS1 gene that causes salt sensitivity and develops a molecular marker to improve salt tolerance in breeding programs.

This study identifies EFNA4 amplification as a driver of lung adenocarcinoma lymph node metastasis through genomic analysis and functional experiments.

This study investigates how the H172Y mutation in SARS-CoV-2 Mpro reduces nirmatrelvir efficacy using simulations, AI, and experiments, revealing structural and functional changes in the enzyme.

This study identifies H2BFWT's role in spermatogenesis by showing its impact on nucleosome stability and gene expression through structural and functional analyses.

The paper identifies genetic and regulatory mechanisms underlying heterosis in the rice hybrid Y900 by analyzing genome and transcriptome data from its parental lines.

This study shows that helper NLR NRG1 forms oligomeric complexes with EDS1 and SAG101 at the plasma membrane upon co-activation of intracellular and cell surface receptors.

This study shows benzidine promotes bladder cancer cell proliferation via the ERK5 pathway by increasing cyclin D1 and PCNA while decreasing p21.

The paper shows skin mesenchymal niches protect AML-initiating stem cells from chemotherapy and promote chemoresistance in a mouse model.

The paper identifies Gli1+ perivascular fibroblasts as a key cell source for wound healing, showing their role in myofibroblast differentiation and wound contraction.

This paper presents a vacuum-actuated soft robot inspired by Drosophila larvae that replicates peristaltic crawling behavior and reproduces experimental findings on crawling speed and mechanics.

This study identifies bZIP25 and bZIP53 as transcription factors regulating pavement and trichome cell development in Arabidopsis thaliana using single-cell RNA-sequencing.

This study implants graphene quantum dots in PEGylated nanoparticles to enhance in vivo imaging and tumor detection, showing improved circulation and tumor accumulation.

The paper identifies heterogeneous tuft cells in injured lungs that develop independently of Type 2 cytokines and are not essential for dysplastic repair.

The paper shows that microbial signals, MyD88, and lymphotoxin contribute to TNF-independent intestinal injury after A20 and Abin-1 deletion in intestinal epithelial cells.

The paper introduces Mal-Seq, a chemical method to sequence 5-formylcytosine (f5C) on RNA, and shows its presence in mammalian mitochondrial tRNA but not in lower eukaryotes.

This study identifies acetylation as a regulatory mechanism in antibiotic resistance in E. coli, showing it negatively affects metabolism but positively influences motility, with PykF acetylation playing a key role.

This study identifies PIMT as a suppressor of endothelial activation and vascular inflammation by methylating TRAF6, inhibiting its function and reducing ICAM-1 expression.

The paper identifies keystone species in synthetic microbial biofilm communities that influence their productivity through metabolic facilitation or competition.

The paper introduces a global collaborative network to standardize soil animal community monitoring and food web analysis across diverse ecosystems.

This study identifies PBP2 as the primary target of cephalosporins in C. difficile and reveals a unique Zn2+-binding motif in PBP2 and related PBPs that contributes to cephalosporin resistance and sporulation.

This study identifies Arl15 as a regulator of TGFβ signaling by promoting Smad-complex assembly through its interaction with Smad4.

This study identifies a new structural class of fungal effectors in Fusarium oxysporum f. sp. lycopersici using experimental and computational methods, revealing structural relationships and immune recognition mechanisms.

This paper tests a computational model's ability to generalize from visual to olfactory navigation in insects and shows how a neural mechanism enables robust navigation across sensory inputs.

This paper develops a type 2 diabetes model in nude athymic rats using high-fat diet and streptozotocin, showing features of diabetic cardiomyopathy suitable for xenograft studies.