Y. Li

This paper identifies the molecular mechanism of Jin Ning Fang's anti-lung cancer effect using network pharmacology and experimental validation, revealing key targets and compounds involved.

The paper investigates how herbivory and nutrient availability fluctuations interact to affect alien plant dominance in synthetic communities.

This study identifies rhizosphere metabolites and microbial shifts in alfalfa soils under continuous cropping, showing autotoxic substances like p-coumaric acid contribute to crop obstacles.

The paper identifies non-reproducible antibody-antigen interactions in clinical sera and develops a model to explain them, improving serological testing for viral infections like COVID-19.

The paper identifies lncEry, a long non-coding RNA that regulates mouse erythroid differentiation and maturation by interacting with WDR82 to control Klf1 and globin gene transcription.

The paper develops a sensitive and specific real-time PCR assay for detecting novel-goose parvovirus in vitro and in vivo, showing high sensitivity and reproducibility.

This study uses dual-lipid metabolomics to compare lipid compositions of MTB and MB and their effects on bovine alveolar macrophages, revealing distinct metabolic responses and colonization mechanisms.

This study shows SAFA interacts with antiviral RNAs to open chromatin and enhance immune gene expression during viral infection.

This study shows that feeding Atlantic salmon insect meal diets alters their intestinal microbiota, with reduced digesta diversity and increased mucosa diversity.

This study identifies plakoglobin and HMGB1 as key mediators of TcdB-induced intestinal epithelial cell apoptosis through mitochondrial pathways.

This study investigates the association between enteric viral infections and idiopathic chronic diarrhea in rhesus macaques, finding no strong link between detected viruses and the condition.

This study identifies TMEM-120/TMEM120A as a conserved protein that promotes fat storage by enhancing triacylglycerol synthesis and lipid droplet expansion in C. elegans and mammalian cells.

ASER compiles sex reversal data from 18 species, including genes, regulatory networks, RNA-seq, and ISH images, to support research on animal breeding and human health.

The paper investigates the distribution of enteric virus nucleic acids in the digestive tract of rhesus macaques with idiopathic chronic diarrhea, finding distinct patterns by viral family and anatomical location.

This study characterizes the structure and function of TMPRSS2, a protease involved in SARS-CoV-2 activation, and identifies features for developing selective inhibitors.

This paper demonstrates a genotype-independent in vivo haploid induction system in dicot crops by mutating DMP genes, achieving HI rates of 1.9%, 2.4%, and 1.2% in tomato, rapeseed, and tobacco respectively.

This study shows that WWP1 deficiency protects against cardiac remodeling and function decline caused by simulated microgravity in mice.

This study demonstrates that stem cell-derived secretome reduces intraocular pressure and protects retinal ganglion cells in glaucoma models through COX2-PGE2 pathway activation and extracellular matrix remodeling.

The paper detects pigeon circovirus in ticks collected from sheep and camels in Inner Mongolia using high-throughput sequencing and PCR, revealing its genomic sequence and phylogenetic classification.

The paper introduces a single-cell cyclic multiplex in situ tagging (CycMIST) technology to comprehensively profile functional proteins in single neurons, demonstrating its ability to detect 182 proteins in a neuron cell line and reveal differential expression in an Alzheimer's disease model.

This study identifies new CCHFV strains in Inner Mongolia, China, showing genetic similarities to strains from Xinjiang and South Africa, suggesting long-term prevalence in the region.

This study examines immune cell profiles in COVID-19 survivors with and without pulmonary sequelae one year post-discharge, identifying immune imbalances linked to residual lung damage.

This study determines the structure of the Scap/Insig-2 complex in the absence of 25HC, revealing structural insights into cholesterol sensing and regulatory mechanisms.

The paper analyzes structural genomic variations in cancer cells to understand how mutational processes influence cell-to-cell genomic diversity and tumor evolution.

This study profiles the tumor immune microenvironment of NSCLC using multiplex immunofluorescence, identifying three immune subtypes and an immune-related risk score for prognosis prediction.

The paper examines mitochondrial structure and function in the least shrew, revealing organ-specific adaptations in mitochondrial networks and protein composition related to metabolic demand.

This study identifies NtMED25 as a mediator subunit that interacts with NtMYC2s to regulate nicotine biosynthesis in Nicotiana tabacum by enhancing gene expression.

The paper develops a defined medium (NLDM) for cultivating soil bacteria and profiling exometabolites, showing it supports growth of 53 diverse isolates and enables metabolite tracking via LC-MS/MS.

The paper identifies a novel binding site on α-tubulin and shows that cevipabulin binding to this site induces tubulin degradation.

The paper identifies a new ERGIC-ERES membrane contact mediated by TMED9 and SEC12 that is essential for autophagosome biogenesis under stress.