Y. Xu

This meta-analysis examines the impact of postoperative radiotherapy waiting time on high-grade glioma prognosis and finds no significant association with overall survival.

This study investigates the role of DNA methylation in persister formation in UPEC, showing that the dam mutant has a defect in persister formation and identifies associated transcriptional and metabolic changes.

This study identifies a novel G protein-biased and subtype-selective agonist for the 5-HT2C receptor from herbal extracts, showing efficacy in weight loss similar to lorcaserin.

This paper improves the kinetic performance of an algal DGAT1 enzyme by fusing it with an ACBP, enhancing acyl-CoA affinity and oil accumulation in yeast and plants.

The paper identifies OBERON3 and SUPPRESSOR OF MAX2 1-LIKE proteins as a regulatory module that establishes phloem identity in Arabidopsis thaliana through chromatin remodeling and gene expression.

The paper shows STAT3 localizes in mitochondria-associated ER membranes, not mitochondria, and other mitochondrial TFs also localize to MAMs.

This study identifies ZBED2 as a transcriptional repressor that antagonizes IRF1 to modulate cell identity and suppress interferon response in pancreatic cancer.

This study identifies RpvA, a LysR-type regulator in S. aureus, which controls persister formation and virulence by modulating metabolism and virulence gene expression.

The paper introduces MiDAS 3, a 16S rRNA gene reference database for activated sludge and anaerobic digesters, and updates the MiDAS Field Guide with species-level taxonomy and functional information.

This study shows that squamous trans-differentiation of pancreatic cancer cells promotes stromal inflammation by converting pancreatic stellate cells into inflammatory CAFs via TP63-dependent mechanisms.

This study reveals how the intrinsically disordered substrate-recognition domain of RNF4 adopts a defined 3D architecture to facilitate SUMO binding and ubiquitin transfer.

This study uses CRISPRi assays to analyze the thermodynamic factors influencing FnCas12a DNA binding, identifying key determinants for improving crRNA design and reducing off-target effects.

This study shows that TLR2 signaling reduces S. uberis infection severity by promoting mitochondrial reactive oxygen species production in mammary epithelial cells.

This study identifies LAMCORE cells as the source of lymphangioleiomyomatosis, showing their uterine neural crest origin and identifying potential biomarkers and therapeutic targets.

This paper uses single-cell RNA sequencing to characterize neutrophil heterogeneity and maturation during homeostasis and bacterial infection, revealing distinct subsets and their functional transitions.

The paper identifies a genomic region Lyb-2-4 associated with hypervirulence in carbapenem-resistant Acinetobacter baumannii, showing higher mortality in infected patients and mice.

This study identifies an aromatic pathway in CLC proteins that enables H+ transport and gating, revealing distinct and conserved routes for Cl- and H+ movement.

The paper investigates the phylogenetic placement of mitochondria within Alphaproteobacteria using alternative methods to address compositional heterogeneity.

This study uses metagenomic Nanopore sequencing to detect influenza virus in clinical respiratory samples, achieving high sensitivity and complete genome sequencing.

The paper uses solid-state NMR to study a constitutively open mutant of KcsA, finding reduced potassium binding affinity at the selectivity filter, supporting allosteric coupling in C-type inactivation.

This paper examines how varying proportions of soft rock and sand affect soil organic carbon mineralization and particle composition, finding that ratios of 1:5 to 1:2 enhance organic carbon accumulation and stability.

This study characterizes the parasitic effect of Phanerochaete chrysosporium strain B-22 on Meloidogyne incognita life stages and demonstrates its efficacy as a biocontrol agent for tomato plants.

The paper develops a redox proteomics method to globally quantify protein oxidation, showing its application in HLRCC cells and demonstrating its utility in analyzing redox signaling.

This study systematically analyzes the distribution of metabolic pathways for five bacterial energy reserves across 8214 proteomes to reveal evolutionary patterns and correlations with genome reduction.

The paper identifies Dnmt3aos as a lncRNA regulating Dnmt3a expression and DNA methylation in macrophage polarization, revealing its role in modulating IFN-gamma expression.

The paper identifies core microbiota for flavor production in Chinese liquor fermentation and constructs a synthetic microbiota that replicates natural flavor metabolism and environmental interactions.

This study compares the venom effectiveness of fire ant queens and workers, finding queen venoms act faster to knock down competitors than worker venoms.

This study shows Munc18-1 facilitates SNARE assembly by forming a template complex, and similar mechanisms are used by other SM proteins.

This study shows that obesity-induced metabolically activated macrophages in mammary adipose tissue promote triple-negative breast cancer stemness and tumorigenesis through GP130 signaling.

This study shows that autophagy reduces lung injury by inhibiting the NF-κB pathway and inflammatory mediator release in hypoxia models.