F. Qi

SARS-CoV-2 vaccination during pregnancy enhances hippocampal neurogenesis and working memory in offspring via IFN-gamma responsive microglia

This study shows maternal SARS-CoV-2 vaccination increases hippocampal neurogenesis and working memory in offspring mice via IFN-gamma responsive microglia.

mRNA Vaccine-Induced SARS-CoV-2 Spike-Specific IFN-γ and IL-2 T-cell Responses are Predictive of Serological Neutralization and are Transiently Enhanced by Pre-Existing Cross-Reactive Immunity

This study examines how mRNA vaccine-induced T-cell responses correlate with neutralizing antibodies and how pre-existing immunity affects vaccine responses over time.

EF-P and its paralog EfpL (YeiP) differentially control translation of proline containing sequences

This study identifies EfpL as a ribosome rescue factor that senses cellular metabolic state, complementing EF-P in proline-containing sequence translation.

The Effects of Different Fatigue Types on Action Anticipation and Physical Performance in High-level Volleyball Players

This study investigates how different fatigue types affect action anticipation and physical performance in volleyball players, finding that dual fatigue has the most significant negative impact.

Immunogenicity of COVID-19 vaccines and their effect on the HIV reservoir in older people with HIV

This study evaluates the immunogenicity of COVID-19 vaccines in older people with HIV and their impact on HIV reservoirs, finding that three doses are needed for optimal neutralizing responses but vaccines may increase HIV reservoirs in those with persistent viremia.

Amphipathic Bax core dimer forms part of apoptotic pore wall in the mitochondrial membrane

This study determines the structure of the Bax core dimer and shows it forms part of the mitochondrial pore wall during apoptosis.

Lack of Reinfection in Rhesus Macaques Infected with SARS-CoV-2

This study shows that rhesus macaques infected with SARS-CoV-2 are protected from reinfection during early recovery, likely due to enhanced neutralizing antibodies.

Ocular conjunctival inoculation of SARS-CoV-2 can cause mild COVID-19 in Rhesus macaques

This study shows that SARS-CoV-2 can cause mild COVID-19 in rhesus macaques through conjunctival inoculation, with distinct viral dispersion patterns compared to intratracheal inoculation.

Inhibition of SARS-CoV-2 infection (previously 2019-nCoV) by a highly potent pan-coronavirus fusion inhibitor targeting its spike protein that harbors a high capacity to mediate membrane fusion

This paper identifies EK1C4, a potent fusion inhibitor against SARS-CoV-2 and other coronaviruses, showing high efficacy in vitro and in vivo.

Single cell RNA sequencing of 13 human tissues identify cell types and receptors of human coronaviruses

The Pathogenicity of SARS-CoV-2 in hACE2 Transgenic Mice

This study infects hACE2 transgenic mice with SARS-CoV-2 and observes pathogenic effects, confirming Koch's postulates and establishing a model for vaccine and therapeutic development.

Integrated RNA and metabolite profiling of urine liquid biopsies for prostate cancer biomarker discovery

The paper identifies urine-enriched RNAs and metabolites in prostate cancer patients and normal individuals, revealing altered glutamate metabolism and TCA cycle in cancer cells.

Compartmentalized Biosynthesis of Mycophenolic Acid

This paper elucidates the compartmentalized biosynthetic pathway of mycophenolic acid, revealing subcellular localization of enzymes and cooperation with β-oxidation machinery.