L. Liu

The paper identifies potent SARS-CoV-2 neutralizing antibodies from a pre-pandemic human antibody library, showing high somatic hypermutation and specific binding to the spike protein.

The paper uses single-cell multi-omics to analyze HCC cell lines, identifying metastasis potential heterogeneity and a hypoxic subgroup with poor prognosis.

This study shows NDRG2 maintains intestinal epithelial barriers by regulating E-cadherin and adherens junctions, preventing colitis and tumor development.

The paper uses molecular and morphological data to clarify species boundaries in Betula section Costatae, identifying a new species, Betula buggsii, within the group.

This study identifies the transferrin receptor (TfR) as an additional receptor for SARS-CoV-2 entry, showing that TfR-mediated infection can occur independently of ACE2 and that targeting TfR has anti-viral effects.

The paper demonstrates that NC410, a LAIR-2 Fc protein, blocks LAIR-1-collagen interaction, enhancing T cell activity and reducing tumor growth in humanized models.

This study identifies sAB-K29, a tool to detect K29-linked polyubiquitin, and shows its role in proteotoxic stress response and cell cycle regulation.

The paper tests hypotheses about genetic diversity patterns in Betula albosinensis, finding support for the central-marginal hypothesis and the role of multiple glacial refugia.

This study investigates how MFG-E8 signaling contributes to age-related arterial damage, showing that its deficiency reduces elastolysis, fibrosis, and calcification in mice.

This study investigates how platelet-activating factor (PAF) affects the barrier function of ARPE-19 cells by altering tight junctions and VEGF expression.

This study develops VLP-based vaccines targeting the HIV-1 FP8 epitope, showing they induce high-titer FP8-specific antibodies and effective neutralizing responses in mice.

This study finds that patients with severe SARS-CoV-2 disease have higher antibody titers against viral proteins and neutralization capabilities compared to less severe cases.

This study evaluates the impact of preoperative α-blocker use on outcomes in extra-adrenal retroperitoneal paraganglioma surgeries, finding no significant differences in postoperative complications.

This paper introduces a physics-based dynamic model of human movement with 48 degrees of freedom to analyze and simulate bipedal movements, supporting applications in biomechanics and virtual reality.

This study examines how SARS-CoV-2 mutations affect protein structures and intraviral interactions, identifying mutations that cause structural changes and alter binding affinity and hot spots.

The paper integrates multiple regulatory data types in Arabidopsis to build an iGRN that predicts gene regulatory interactions and identifies novel ROS signaling regulators.

This study investigates how different surface topographies of biomaterial scaffolds affect skin wound healing in mice, finding that aligned scaffolds enhance regeneration and modulate immune responses.

The paper describes a genetically adapted Pseudomonas aeruginosa small colony variant causing persistent bacterial coinfection in a COVID-19 patient, showing enhanced biofilm formation and quorum sensing.

This study shows an inactivated SARS-CoV-2 vaccine induces neutralizing antibodies and CTL responses in rhesus macaques, effectively preventing viral replication and lung inflammation.

The paper isolates and characterizes 61 SARS-CoV-2-neutralizing monoclonal antibodies from infected patients, identifying potent antibodies targeting multiple epitopes on the spike protein.

This study develops a virus-free live-cell visualization system for SARS-CoV-2 entry using a fluorescent spike trimer probe, enabling analysis of neutralizing antibodies and inhibitors.

This study investigates L-arabinose's antifeedant effects on cotton bollworm caterpillars, showing it deters feeding, suppresses gustatory responses, and inhibits sucrase activity.

This study shows that deleting Nupr1 in HSCs activates quiescence, enhancing engraftment without affecting stemness or differentiation.

The paper develops biotin-labeled SARS-CoV-2 spike molecular probes using structure-based design and purification methods, achieving high yields and enabling antibody characterization.

This study identifies that heme absence at the catalytic site of HO2 triggers its lysosomal degradation, distinct from other HRM-containing proteins and HO1.

This study evaluates how the radiated brain microenvironment affects the growth of nine human glioblastoma cell lines, finding that some tumors grow faster while others grow slower in this environment.

This study investigates the factors causing unresolved phylogenetic relationships in Malpighiales, finding that gene tree heterogeneity arises from incomplete lineage sorting, gene tree estimation error, and ancient gene flow.

This study identifies three Npl4 conformational states in the human p97 complex using cryo-EM and shows how a disulfiram derivative inhibits p97 by disrupting Npl4 zinc finger interactions.

This study shows that altered N-glycan composition in Chlamydomonas reinhardtii reduces flagella-mediated adhesion and surface binding.

This study identifies heparan sulfate proteoglycans as an attachment factor for SARS-CoV-2 and suggests HS oligosaccharides could inhibit viral binding.