L. Yang

This study introduces a new remote sensing index for urban ecological monitoring by integrating air quality data with existing ecological factors, showing improved assessment in Beijing.

This study shows that music increases protein content and photosynthetic efficiency in duckweed and activates Glu and Ca signaling, with transcriptomic changes linked to metabolic pathways.

This study evaluates the effectiveness of WT and variant-specific mRNA vaccines against SARS-CoV-2 Omicron BA.2 subvariant using vaccinated serum from animals.

This study identifies genomic rearrangements and regulatory changes in the little skate that contribute to the evolution of wing-like fin appendages.

This study develops RAMIHM, a method to generate potent human monoclonal antibodies against SARS-CoV-2 Omicron using mRNA immunization of humanized mice, identifying three highly effective antibodies.

The paper identifies a small molecule inhibitor of PDE6D-RAS interaction that shows anti-leukemic effects by blocking RAC activation in RAS-mutated cells.

This study evaluates the neutralization efficacy of antibodies against SARS-CoV-2 Omicron and other variants, finding that antibody 8G3 maintains broad neutralizing activity while EUA antibodies lose effectiveness.

This study evaluates an Omicron-specific mRNA vaccine, showing it elicits strong antibody responses and outperforms WT boosters against Omicron and Delta variants.

LIFE-Seq is a method for analyzing transgene integration in GMOs using DNA probes and PacBio sequencing, offering improved accuracy and cost-effectiveness compared to whole-genome sequencing.

This study evaluates ACE2-Fc combined with neutralizing antibodies against SARS-CoV-2 variants, showing enhanced neutralization and resistance to escape mutations.

This study identifies novel viral genomic components and evolutionary patterns using conserved untranslated regions (UTRs) and UTR-backed iterative BLASTn in multipartite viruses.

The paper introduces a rapid, highly multiplexed protein detection method for brain tissue, enabling simultaneous detection of 31 proteins in 2 hours with high sensitivity and resolution.

This paper introduces a high-multiplex single-cell proteomics technology called Cyclic MIST to measure 465 proteins, enabling comprehensive immune cell subpopulation classification.

This study shows that homologous or heterologous boosters of inactivated vaccines increase neutralizing antibodies against SARS-CoV-2 Omicron, reducing escape from neutralization.

The paper investigates how intramolecular epistasis affects the evolution of CTS-resistant Na,K-ATPases, finding that resistance substitutions have pleiotropic effects independent of sequence divergence.

This paper describes a new early-branching armoured dinosaur from the Lower Jurassic of China, providing insights into the early diversification of thyreophorans.

The paper identifies two transporters that regulate mitochondrial Zn2+ levels in C. elegans, showing their roles in maintaining mitochondrial homeostasis.

The paper develops genetically encoded fluorescent potassium indicators with tunable binding affinities through structure-guided design and genome mining, showing varying Kd values in vitro and in cells.

This study quantifies TCA flux in tumors and healthy tissues, finding suppressed ATP production in tumors despite increased glycolysis.

This study assesses the future suitability of breadfruit cultivation under climate change scenarios, finding potential for expansion in sub-Saharan Africa but reduced yield quality under high emission scenarios.

The paper shows mechanical loading and hyperosmolarity reset circadian clocks in skeletal tissues via the mTORC2-AKT-GSK3β pathway, inducing rhythmic gene expression.

The paper investigates SARS-CoV2-induced inflammatory responses in monocytes using in vitro co-cultures, identifying a virus-specific gene cluster distinct from other viruses.

This study evaluates eVLP-based vaccine candidates against SARS-CoV-2 variants, showing that a trivalent vaccine induces broader immunity compared to single-variant vaccines.

This study shows that inhibiting stromal Galectin-3 enhances chemotherapy effectiveness in BCP-ALL by disrupting leukemia cell migration, adhesion, and drug resistance.

This paper identifies a monoclonal antibody, 2G1, that neutralizes all SARS-CoV-2 variants with high potency and describes its mechanism of action and therapeutic efficacy in animal models.

This study shows Galectin-1 and Galectin-3 promote BCP-ALL cell growth and survival through intrinsic and extrinsic mechanisms, and their inhibition increases chemotherapy sensitivity.

This study identifies genetic transcript regulation and cyclohexane release as factors enhancing duckweed regeneration through callus formation.

The paper identifies non-reproducible antibody-antigen interactions in clinical sera and develops a model to explain them, improving serological testing for viral infections like COVID-19.

This paper presents a data-driven workflow to design microbial strains using aggregated ALE mutational data, revealing gene-centric mutations that significantly alter cellular states.

The paper identifies lncEry, a long non-coding RNA that regulates mouse erythroid differentiation and maturation by interacting with WDR82 to control Klf1 and globin gene transcription.