M. Zhang

This study investigates how angioplasty induces epigenomic changes in rats, revealing BRD4 and EZH2's roles in regulating neointimal hyperplasia through histone modifications.

This study identifies a conserved exZZU extension in ankyrins that enhances binding to beta-spectrins through structural interactions, but shows that direct binding does not determine pairing specificity.

This study identifies a non-hypermucoviscous ST11 hypervirulent K. pneumoniae strain lacking classical virulence factors, showing increased virulence through ampR and WcaJ mechanisms.

The paper profiles miRNAs and uses degradome sequencing to study their role in CMS regulation during anther development in pepper, identifying differentially expressed miRNAs and their target transcripts.

This study examines the effects of atrazine exposure on DNA methylation and gene expression in zebrafish, identifying specific genes and pathways affected by the herbicide.

This study shows that a diversified learning environment improves active avoidance learning and mitigates stress-induced learning impairments in animals.

This paper introduces GNEPS, a fluorescent sensor that detects intracellular GTP:GDP ratios in real-time, showing its utility in monitoring metabolic changes across cell types and organelles.

The paper introduces a microtubule probe that enables correlative super-resolution fluorescence and electron microscopy to study microtubule ultrastructure.

This study shows that GIT1 and β-Pix form a condensed enzyme complex via phase separation, enabling compartmentalized signaling in different cellular contexts.

This study shows that deleting GCN5L1 in cardiomyocytes reduces cardiac functional decline in HFD mice by enhancing substrate flexibility and reducing oxidative damage.

This study uses internet search data to show seasonal variation in cancer recurrence queries, with peaks in early summer (northern hemisphere) and late summer (southern hemisphere).

This study demonstrates that transient expression of Runx1 and Hoxa9 in pluripotent stem cells generates functional T cells capable of immune surveillance and tumor eradication.

This study applies r- and K-selection to HeLa cells to show how life history strategies influence tumor functional diversity through gene expression and ecological competition.

This study identifies EccE1 as a critical membrane protein required for ESX-1 function and stabilization of ESX-1 membrane proteins in Mycobacterium tuberculosis, with deletion of eccE1 reducing levels of other ESX-1 components and attenuating bacterial virulence.

The paper investigates the association between epidermal green autofluorescence intensity and serum cytokine levels in LPS-exposed mice, finding significant correlations with multiple inflammatory and anti-inflammatory cytokines.

This study optimizes fertigation for greenhouse strawberries by identifying the optimal levels of N, P, K, and water to maximize yield and SSC/TA ratio.

This paper develops a STED system for 3D super-resolution imaging in living mice, achieving depths of 76 micrometers in brain tissue.

The paper analyzes ancient DNA from museum specimens to show that Southern Chinese gray wolves form a distinct sub-population with genetic links to an extinct canid related to dholes.

This study describes the sexual stage of Venturia effusa, demonstrating its heterothallic nature and recombination through experimental mating type pairing and ascospore progeny analysis.

This study develops WGA-pHRho, a fluorescent pH sensor to visualize proton fluxes on the extracellular surface of cells, showing correlation between pH changes and proton channel activity.

The paper identifies a genomic region Lyb-2-4 associated with hypervirulence in carbapenem-resistant Acinetobacter baumannii, showing higher mortality in infected patients and mice.

This study identifies the BD2 domain of BRD4 as critical for EndoMT and vein graft neointima formation, suggesting it as a therapeutic target.

This study shows BRD2 and SREBP2 work together to increase sigma-2 receptor expression when cells lack cytosolic cholesterol.

This study identifies gut microbiome biomarkers associated with obesity in Shenzhen adolescents and finds gender-specific differences in microbiome composition and function.

This study shows that absence of geomagnetic field reduces feeding in brown planthopper nymphs, leading to lower body weight and altered glucose levels and appetite-related gene expression.

This study shows that inhibiting DOT1L reduces intimal hyperplasia in rat carotid arteries by lowering H3K79 methylation levels.

This paper investigates the biosynthesis of formycin A and pyrazofurin A, identifying key enzymes and pathways involved in their C-nucleoside scaffold construction.

This paper develops a hierarchical Bayesian model to detect linear temporal changes in antibiotic resistance by accounting for censored MIC data and non-resistant population trends.

The paper identifies specific target proteins bound by WW domain tandems of KIBRA and MAGI with high affinity and specificity, revealing new binding partners and mechanisms.

The paper identifies Dnmt3aos as a lncRNA regulating Dnmt3a expression and DNA methylation in macrophage polarization, revealing its role in modulating IFN-gamma expression.