Q. Li

This study uses imaging mass cytometry to analyze tumor-immune microenvironments in melanoma patients, identifying distinct microenvironment archetypes linked to responses to anti-PD-1 therapy.

This paper develops an engineered A549 cell model overexpressing ACE2 and TMPRSS2 to study SARS-CoV-2 infection and antiviral responses.

Antibodies from 3-dose vaccinated individuals neutralize Omicron and other variants, with some being ultrapotent and broadly reactive.

This study examines the long-term effects of soy lecithin exposure on gut microbiota from individuals with high and low emulsifier sensitivity using the M-SHIME model.

This study compares the effects of rhamnolipids and TWEEN80 on gut microbiota composition and function in the SHIME system, showing opposite impacts and highlighting donor-dependent responses.

This study identifies how Omicron evades neutralizing antibodies by analyzing mutations and their effects on different epitope groups, showing over 85% of tested antibodies are escaped.

This study extracts and purifies β-2,7,11-cembratriene-4,6-diol from tobacco leaves and demonstrates its antiviral activity against TMV through in vivo and molecular assays.

This study shows that Igf1 deletion in TMJ fibrocartilage stem cells causes cartilage degeneration and worsens osteoarthritis in mice.

The paper uses long-read sequencing to identify novel transcripts and isoform changes in primate transcriptomes, highlighting immune-related regulatory divergence.

The paper applies deep learning to identify anther dehiscence states in cotton to screen for heat-tolerant varieties and support genetic breeding research.

This study investigates how recurrent UTI and estrogen influence the urobiome's taxonomic and functional features in postmenopausal women using metagenomic and metabolomic analyses.

This study investigates how ACE2 and antibodies affect the conformational dynamics of the SARS-CoV-2 spike protein using smFRET and FCS, revealing that D614G modulates RBD energetics similar to ACE2 binding.

This study uses multi-omics analysis to show that RVE8-like proteins in Arabidopsis affect carbohydrate metabolism and proteasome activity, leading to altered plant growth and physiology.

This study uses spatial transcriptomics to analyze invasive fronts in solid tumors, identifying immune cell enrichment, metabolic changes, and poor prognosis factors.

This study uses a semi-synthesis approach to generate N-terminal acetylated HMGB1 proteins and shows that this modification affects its interaction with heparin and stability.

This study identifies pathogen-dependent sources of type I and III IFNs during respiratory virus infection, showing that pDCs produce IFN-{lambda} during IAV infection but not NDV.

This study identifies a novel cannibalism mechanism in Bacillus velezensis SQR9 mediated by bacillunoic acids, enhancing biofilm formation and interspecies competition through a two-component regulatory system.

This study identifies a bacterial system using PrfH and RtcB to rescue and repair stalled ribosomes caused by damage in the decoding center.

This study shows that Zika virus causes placental pyroptosis via GSDME activation, leading to adverse fetal outcomes.

This study identifies a non-bactericidal cathelicidin, PopuCATH, that prevents bacterial infection by enhancing phagocyte influx and reducing inflammation without direct antimicrobial activity.

This study identifies and characterizes Aeromonas species in farmed loaches from China, finding high prevalence of A. veronii and resistance to multiple antibiotics.

This study identifies specific HA mutations in H9N2 avian influenza virus that influence antigenic variation and immune escape from vaccine antibodies.

This study shows hyposalinity stress and Vibrio infection synergistically cause oyster mortality by disrupting microbial balance and triggering immune dysregulation.

This study simulates reentrant arrhythmias in ischemic hearts with multiple electrophysiological remodelling stages, showing that spatial heterogeneity of refractory periods and excitation threshold differences drive reentry depending on border orientation relative to wavefronts.

This study constructs and analyzes Stroke Symptom-Herb Networks (SSHNs) from historical TCM prescriptions to reveal their dynamic structure and evolutionary trends over 1700 years.

This study shows that soil inoculum origin and amount affect microbiome and plant community development in degraded grasslands over three years.

The paper quantifies grazing abilities of thirty-nine mixotrophic phytoplankton isolates from the North Pacific Subtropical Gyre, revealing functional diversity in their consumption of Prochlorococcus.

The paper measures traction forces and actomyosin dynamics in stress fibers, revealing that actin turnover and traction forces depend on both myosin II and formin activities.

The paper determines the cryo-EM structure of prion fibrils from a familial prion disease, supporting the conformational adaptability model of transmissibility barriers.

This study shows that reducing DAF-2 in the intestine of C. elegans nearly doubles lifespan without affecting development or reproduction.