X. Wang

This study shows that CCR1 activation on respiratory epithelial cells suppresses RSV replication via Gi-mediated inhibition of STAT3 phosphorylation and HSP90 activity, independent of IFN-I.

This study improves plant growth-promotion by engineering specialized bacterial mutants within a single species and assembling them into consortia that enhance root colonization and disease resistance.

This study shows that high salinity activates CEF and reduces state transitions in three Chlamydomonas species, with psychrophilic species showing the highest CEF rates.

The paper introduces cgRNASP, a series of coarse-grained statistical potentials for RNA 3D structure evaluation, showing comparable or better performance than all-atom methods with higher efficiency.

This study identifies HERV activation in BA livers and shows it re-educates macrophages, impairing neutrophil recruitment and causing liver damage, suggesting therapeutic targets.

This study identifies 4-vinylanisole as an aggregation pheromone that promotes sexual maturation synchrony in gregarious female locusts through a juvenile hormone/vitellogenin pathway.

This study identifies TFAM-dependent mitochondrial integrity in Tregs as critical for preserving immune homeostasis and preventing inflammaging.

This study identifies alnustone as a drug that inhibits Streptococcus pneumoniae virulence by targeting pneumolysin and sortase A, reducing biofilm formation and protecting against infection.

This study identifies critical ecological protection areas in Aksu City and Wensu County by simulating human activity impacts and analyzing resistance surfaces across different scenarios.

This study uses TnSeq to identify genes required for swarming motility in Bacillus subtilis, finding known flagellar genes, previously reported regulators, and 36 additional genes that enhance swarming.

This study identifies Ruminococcus gnavus as a gut bacterium that contributes to IBS-D by increasing serotonin biosynthesis through phenethylamine production.

This paper reports chromosome-level genome assemblies of five Sitopsis species and identifies the B-subgenome donor of bread wheat as an extinct species closely related to Ae. speltoides.

This study characterizes the HERV-K (HML-8) group in the human genome, identifying 40 proviruses and 5 solo LTR elements and determining their integration time and genomic distribution.

This paper develops lyophilized mRNA-lipid nanoparticle vaccines that maintain stability at room temperature and show high antigenicity against SARS-CoV-2 variants in preclinical and human trials.

The paper identifies CD36 homologs as conserved lipid receptors mediating anti-Borrelia immunity in both ticks and humans.

The paper uses proteomics to compare immune responses to Salmonella Typhimurium infection in two mouse strains, identifying differentially expressed proteins and pathways involved in resistance.

This study shows that BA.2 causes stronger antibody evasion than BA.1, particularly in SARS convalescents, and identifies key mutations responsible for this escape.

This study identifies Zfp335 as a transcription factor regulating T cell development by controlling TCRβ expression and cell survival through β-selection-dependent and -independent mechanisms.

The paper shows that phosphatidic acid, produced by phospholipase Dδ, mediates the nuclear translocation of cytosolic GAPC under heat stress in plants.

This study compares phenotypic and transcriptomic responses of sun- and shade-loving plants to sunlight and dim-light conditions, finding that shade-loving ginseng shows lower phenotypic plasticity but higher photosynthetic efficiency under dim light.

The paper identifies IMC proteins in Plasmodium yoelii and shows DHHC2 palmitoylates CDPK1 and GAP45 for their localization, essential for schizont development.

This study shows that PD-L1 blockade enhances CAR T cell activity by altering macrophage phenotypes through IFNγ signaling in the tumor microenvironment.

This study identifies ACE2 as the receptor for NeoCoV and PDF-2180-CoV, two close MERS-CoV relatives in bats, showing they can use bat ACE2 and, with mutation, human ACE2.

This study shows that sowing date affects temperature and light conditions during rice growth, which in turn modifies cadmium content in brown rice by regulating Cd-related gene expression.

This study uses molecular barcoding to analyze genetic diversity in Mtb strains, showing L2 strains have distinct growth dynamics and resist BCG vaccination.

This study shows that RfxCas13d causes mouse death by collateral cleavage of 28s rRNA, highlighting biosafety concerns for CRISPR-Cas13 systems.

This study shows that smooth muscle cell clusters form through contractile forces causing brittle fracture and active dewetting, providing insight into SMC-related disorders.

This study identifies HP1β's chromo shadow domain as essential for promoting H2A ubiquitination and BRCA1 recruitment at DNA double-strand breaks to facilitate homologous recombination repair.

This study identifies FAM84B amplification as a marker of poor prognosis in ESCC and shows it promotes cell proliferation by interacting with NPM1 to suppress CDKN2A.

This paper uses NMR-assisted crystallography to determine the protonation states and structure of the tryptophan synthase α-aminoacrylate intermediate, revealing insights into its reactivity and catalytic mechanism.