X. Wang

This study shows that SARS-CoV-1 survivors vaccinated with ZF2001 have reduced neutralization against SARS-CoV-2 Omicron compared to other variants.

This paper identifies a viral protein that inhibits stress granule formation by targeting Nup358/RanBP2, revealing a mechanism by which viruses modulate cellular stress responses to promote infection.

This study tracks white matter changes in SIV-infected rhesus monkeys with and without cART, finding early alterations at 4 weeks and varying cART effects over time.

This study identifies introgressed haplotypes from wild sheep species associated with morphological traits in domestic sheep using whole-genome sequencing.

This study shows that engineering human stem cell-derived islets to secrete tolerogenic cytokines can prevent xeno-rejection without immunosuppression or encapsulation.

This study shows that HPV E6 reduces mitochondrial antioxidant capacity and therapy resistance in oropharyngeal cancer by suppressing the PGC-1α/ERRα pathway.

The paper designs a DNA nanostructure for rapid, sensitive, and inexpensive detection of SARS-CoV-2 and demonstrates its potential to inhibit viral infection.

This study identifies genomic patterns in MPNST evolution linked to clinical outcomes and shows these patterns are detectable in cell-free DNA.

This study identifies FoxP3-mediated inhibition of RyR2 as a mechanism by which regulatory T cells suppress immune responses through reduced calcium signaling and impaired T cell-DC interactions.

The paper identifies two competing bacterial guilds in the gut microbiome that correlate with host health conditions and can classify multiple diseases across diverse populations.

This study develops a regenerative immunotherapy using helminth-derived soluble egg antigen to promote tissue repair in multiple injury models.

This study shows lysine acetylation in E. coli inhibits translation by disrupting ribosome subunit association, linking metabolic state to protein synthesis.

This study develops Stereo-seq, a high-resolution spatial transcriptomic method, to analyze mouse organogenesis and map developmental disease loci.

This study investigates antibody evasion by SARS-CoV-2 Omicron sublineages BA.2.12.1, BA.4, and BA.5 against plasma from vaccination and BA.1 infection, showing increased neutralization escape.

This study investigates the molecular mechanisms of murine GBP2, revealing its lipid-binding affinity and dynamic behavior on membranes, which may contribute to membrane destruction.

This study shows metformin reduces Cyp26a1 expression, increasing atRA levels and decreasing pro-tumor CD8+ T cells, thereby preventing hepatocarcinogenesis in a mouse model.

FebRNA predicts RNA 3D structures using a fragment-ensemble-based approach, achieving reliable results for complex RNA topologies.

This study identifies a chitin-binding protein, CgCBP, highly expressed in the outer fold of the mantle of Pacific oyster Crassostrea gigas, which is linked to shell pigmentation through its role in periostracum structure.

The paper identifies new alleles of the tomato SELF PRUNING gene that alter plant compactness and yield, with sp-5732 increasing yield by up to 42%.

This study shows that interfering with DicVg4 and DicVgR genes in Diaphorina citri reduces vitellogenin accumulation, prevents normal egg formation, and leads to abnormal eggs and nymphs.

The paper identifies nanobodies with broad neutralizing activity against multiple sarbecoviruses and shows their protective efficacy in a mouse model.

This study investigates the structural and biochemical features of Omicron BA.1 and BA.2 variants, showing increased infectivity and mouse ACE2 binding compared to wildtype, suggesting a potential human-cat-mouse-human transmission cycle.

This study identifies the role of renal macrophages in clearing intratubular particles and preventing kidney stone formation through phagocytosis and transmigration.

This study investigates how CaSR mutations cause different disease outcomes by showing that heterodimers reduce WT affinity and rescue mutant trafficking, while homodimers fail to function.

This study quantifies neoantigen-mediated immunoediting stages in cancer evolution across tumor types, showing elimination and escape signals predict immunotherapy response.

This paper introduces a method to chronically image blood microcirculation using liver-secreted fluorescent proteins, enabling long-term observation of vascular functions in mice.

This study compares antibody neutralization efficacy against SARS-CoV-2 Omicron sub-lineages BA.1, BA.1.1, BA.2, and BA.3, showing increased resistance and the benefit of vaccine boosters.

This study shows that knocking out the Angiotensin II Type 1a Receptor in rats reduces high-fat diet-induced obesity by enhancing adipose lipolysis through the cAMP/PKA pathway.

The paper identifies resR as a target of positive selection in Mtb clinical isolates, linking its mutations to antibiotic resilience and treatment failure.

The paper shows that ACE2-expressing macrophages allow SARS-CoV-2 entry and replication, triggering anti-viral responses, while ACE2-negative macrophages do not support viral entry or cytokine release.