Z. Liu

This paper shows that proline hydroxylation and histidine methylation on actin regulate cell motility through a crosstalk mechanism involving PHDs, VHL, and SETD3.

This paper reports the preclinical efficacy of ALD-R491, a vimentin-targeting compound, in treating COVID-19 by reducing viral entry, enhancing pathogen clearance, and suppressing overreactive immune responses.

This study develops a swab-based method to quantitatively measure small molecule recovery on surfaces, demonstrating its use for exposomics and behavioral analysis.

This study develops a single-dose rAAV5-based vaccine that provides long-term immunity against SARS-CoV-2 and its variants with high neutralizing antibody titers and safety.

This study introduces a looped mass transfer system to stabilize microbial communities, showing that it reduces stochastic fluctuations and supports subcommunities with zero net growth.

This study shows SUN1 stabilizes endothelial cell junctions via microtubules, regulating blood vessel formation and barrier function.

This study identifies early megakaryocyte lineage-committed progenitors in adult mouse bone marrow and proposes a differentiation model involving intermediate progenitors.

This study identifies BcPTP1 as a phytotoxic effector secreted by Botrytis cinerea during late infection, which induces cell death and promotes lesion spreading.

The paper calculates folding thermodynamics of WW domain variants using simulations and predicts effects of guanidine hydrochloride concentration changes.

The paper determines the structure of infective Getah virus at 2.8 Å resolution using cryo-EM, revealing glycosylation, S-acylation sites, and lipid interactions critical for immune evasion and host cell invasion.

This study quantifies how Vibrio cholerae lands on surfaces in viscoelastic environments using MSHA pili and flagellum, showing pili act as brakes and anchors during landing.

This study shows TMPRSS2 is a tumor suppressor in lung adenocarcinoma, with its downregulation linked to enhanced antitumor immunity and better response to immunotherapy.

The authors withdrew their manuscript due to irreproducible and non-robust results regarding histone H3 horizontal transfer.

This study reports the structures of S. aureus PgsA at two catalytic states, revealing the mechanism of phosphatidylglycerol biosynthesis and the impact of daptomycin resistance mutations.

This paper demonstrates a genotype-independent in vivo haploid induction system in dicot crops by mutating DMP genes, achieving HI rates of 1.9%, 2.4%, and 1.2% in tomato, rapeseed, and tobacco respectively.

This study shows that WWP1 deficiency protects against cardiac remodeling and function decline caused by simulated microgravity in mice.

This study shows TMEM120A does not mediate poking- or stretch-induced currents and identifies a specific coenzyme A-binding site through cryo-EM structures.

This study identifies Ssn3 kinase substrates involved in hyphal growth repression through Flo8 phosphorylation in C. albicans.

This study uses Raman spectroscopy and machine learning to identify metastatic phenotypes in breast cancer and shows that phenotypic switches can be predicted by spectral analysis.

This study investigates how epigenetic changes in sorghum roots under phosphorus limitation affect root architecture and phosphorus uptake.

The paper shows that Salmonella and Shigella effectors generate PtdIns(3,4)P2 independently of phosphoinositide 3-kinases using a phosphotransferase mechanism.

This study compares inactivity, behavior, and enrichment use in fast- and slower-growing broiler chickens, finding that faster-growing strains are more inactive and use enrichment less, especially at younger ages.

This study shows that error minimization and specificity in the genetic code could emerge as by-products of prebiotic evolution through ribozyme co-option.

This study shows that a common SEC23B mutation in mice causes chronic pancreatitis and growth restriction, highlighting SEC23B's role in pancreatic function and growth hormone sensitivity.

The paper investigates embryo-endosperm signaling in rice using a mutant to identify regulatory pathways affecting endosperm development and proposes a new staging system for rice seed development.

The paper uses spatial transcriptomics to analyze lung cancer heterogeneity, identifying gene expression gradients and tumor subclones, and infers metastasis trajectories through pseudo-time modeling.

The paper identifies an antibody that neutralizes all SARS-CoV-2 variants by targeting a conserved epitope on the spike protein.

This paper introduces a high-resolution imaging system for tracking small animals in multiwell plates, enabling detailed behavioral analysis at scale.

This study identifies novel SARS-CoV-2 receptors through a CRISPR activation screen, revealing LDLRAD3, TMEM30A, and CLEC4G as functional receptors independent of ACE2.