Z. Liu

This study shows that both increased and decreased SUMOylation enhance drought tolerance in apple by modulating MdDREB2A stability through SUMOylation and ubiquitination.

The paper investigates how RNA-binding proteins (RBPs) influence RNA polymerase II activity through phase separation, showing that RBPs like PSPC1 enhance polymerase engagement and transcription.

A vaccine-induced human monoclonal antibody neutralizes SARS-CoV-2 and variants, reducing lung inflammation and viral load in hamsters.

The paper shows that Polycomb repressive complex 2 and Sin3 histone deacetylase complex work together to epigenetically control effector gene expression in Magnaporthe oryzae, regulating its pathogenicity.

This study shows that IL-1β is ubiquitylated and degraded to limit its inflammatory activity, with specific ubiquitin modifications and electrostatic interactions playing key roles.

The paper identifies optimal anchor points on an anticalin scaffold for enhanced binding strength with CTLA-4 using AFM-SMFS and computational modeling.

This study develops a drug-resistant recombinant BCG vaccine that enhances second-line TB treatment efficacy in a murine model of drug-resistant tuberculosis.

The paper reports high-resolution structures of PSI-LHCI-LHCII supercomplex in green algae, revealing the role of LhcbM5 in state transitions and supercomplex formation.

This study characterizes the airway bacterial and fungal microbiome in COPD patients and healthy controls, finding altered microbial diversity and interactions associated with disease severity.

This study compares growth, efficiency, and mortality of 16 broiler chicken strains reared under standardized conditions, finding differences in weight and feed efficiency but not mortality.

This study identifies SnTox5, a necrotrophic effector from P. nodorum that targets wheat's Snn5 gene, facilitating pathogen colonization and programmed cell death.

This study identifies SnTox267, a fungal effector in Parastagonospora nodorum that exploits three host genes to cause disease in wheat by hijacking two distinct pathways.

This study compares the metabolic profiles of sweet potato leaves grown in soil versus hydroponic systems to identify metabolites associated with taste quality differences.

This study evaluates enzalutamide's antiviral efficacy against SARS-CoV-2 in different cell types and mouse models, finding it effective in prostate cancer cells but not in lung cells or organoids.

This paper describes a fully human immunoglobulin from transchromosomic bovines that neutralizes SARS-CoV-2 variants, including those with mutations like E484K and N501Y.

The paper identifies an immune gene signature linked to MGMT methylation in glioblastoma that predicts prognosis and immune response.

This study models O2 transport in tissue during magnetic needle acupuncture and finds that magnetic fields enhance interstitial flow and O2 delivery, particularly in permeable tissues.

This paper evaluates the contribution of fluid movement to oxygen transport in tissue using a physical-phenomenological model, showing its significance in O2-deficient regions and cytoplasm movement.

The paper identifies a conserved antigenic supersite on the SARS-CoV-2 N-terminal domain recognized by neutralizing antibodies and shows its vulnerability to mutations in variants.

The paper identifies and characterizes a novel adipocyte population with active Wnt/β-catenin signaling that influences beige fat formation and glucose homeostasis in mice.

The paper optimizes the production process for a SARS-CoV-2 vaccine candidate, achieving high yield and purity through yeast fermentation and chromatographic purification.

This study determines the structure of the Bax core dimer and shows it forms part of the mitochondrial pore wall during apoptosis.

This study shows that Lkb1 is essential for maintaining vascular smooth muscle cell (VSMC) identity and function in mice, as its deletion leads to vascular abnormalities and aneurysm formation.

This paper introduces an automated pipeline for analyzing dynamic 3D MRI data to assess gastric motility and emptying in healthy humans.

This paper introduces a surface-coating technique to improve DNA sequencing speed, cost, and throughput for genomic applications.

This study uses single-cell RNA sequencing to show that endothelial cells under laminar flow exhibit increased RNA heterogeneity but decreased protein heterogeneity.

The paper shows that bone marrow adipocyte whitening during obesity drives the increase of invasive Ly6Chigh monocytes, preceding adipose tissue macrophage expansion.

This paper describes a multitope protein-peptide vaccine candidate, UB-612, that is immunogenic and prevents lung infection in animal models, with ongoing clinical trials.