Author

B. Ju

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 5 Microbiology· 2 Bioengineering· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 8 Research Focus:host-pathogen & immune response· 5 Organism:human· 5 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Assay:imaging· 2 Organism:mouse· 2 Assay:proteomics· 2

Frequent Co-Authors

Z. Zhang· 6 shared B. Zhou· 4 shared J. Yu· 4 shared L. Zhang· 4 shared X. Ge· 4 shared H. Wang· 3 shared L. Cheng· 3 shared L. Liu· 3 shared

Activity by Year

2020-2022 · peak 5/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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Curved chords = mutual co-authorship

6 shared papersImmunology

Z. Zhang

Mutual co-authors in cluster

Author profile →

9 papers

Recent·Most cited

Molecular basis of broad neutralization against SARS-CoV-2 variants including Omicron by a human antibody

Z. Zhang, B. Ju, Q. Zheng, H. Guo, Q. Fan, T. Li, S. Song, H. Sun, S. Shen, X. Zhou, L. Cheng, W. Xue, L. Cui, B. Zhou, X. Ge, , N. Xia

A human antibody, VacW-209, broadly neutralizes SARS-CoV-2 variants including Omicron by targeting a conserved epitope, highlighting the importance of such antibodies in pandemic control.

bioRxiv · Jan 19, 2022 · PreprintImmunology

Potent antibody immunity to SARS-CoV-2 variants elicited by a third dose of inactivated vaccine

B. Ju, B. Zhou, S. Song, Q. Fan, X. Ge, H. Wang, L. Cheng, H. Guo, D. Shu, L. Liu, Z. Zhang

A third dose of inactivated SARS-CoV-2 vaccine significantly enhances plasma neutralization and generates high-affinity anti-RBD memory B cells against variants like Beta, Delta, and Lambda.

bioRxiv · Nov 10, 2021Immunology

A Developmentally Prometastatic Niche to Hepatoblastoma in Neonatal Liver mediated by the Cxcl1/Cxcr2 Axis

L. Fan, Q. Pan, W. Yang, S. C. Koo, C. Tian, L. Li, M. Lu, A. Brown, B. Ju, J. Easton, S. Ranganathan, S. Shin, A. Bondoc, J. J. Yang, J. Yu, L. Zhu

This study identifies a neonatal liver niche that promotes hepatoblastoma metastasis via the Cxcl1/Cxcr2 axis, showing increased tumor aggressiveness and hypoxia in early postnatal models.

bioRxiv · Oct 22, 2021Cancer Biology

SARS-CoV-2 variants resist antibody neutralization and broaden host ACE2 usage

R. Wang, Q. Zhang, J. Ge, W. Ren, R. Zhang, J. Lan, B. Ju, B. Su, F. Yu, P. Chen, H. Liao, Y. Feng, X. Li, X. Shi, Z. Zhang, , L. Zhang

This study evaluates antibody resistance and ACE2 usage in SARS-CoV-2 variants, finding SA501Y.V2 shows the highest resistance and expanded host range.

bioRxiv · Mar 9, 2021 · PreprintImmunology

Structural basis for bivalent binding and inhibition of SARS-CoV-2 infection by human potent neutralizing antibodies

R. Yan, R. Wang, B. Ju, J. Yu, Y. Zhang, N. Liu, J. Wang, Q. Zhang, P. Chen, B. Zhou, Y. Li, S. Zhang, L. Tian, X. Zhong, L. Cheng, , Q. Zhou

This study reports cryo-EM structures of potent SARS-CoV-2 neutralizing antibodies, revealing bivalent binding mechanisms and their correlation with enhanced neutralization and S1 subunit shedding.

bioRxiv · Oct 13, 2020Microbiology

miR-424(322) is a molecular switch controlling pro-inflammatory vs anti-inflammatory skin DC subset differentiation by modulating TGF-β signaling

V. Zyulina, K.-K. Yan, B. Ju, C. Passegger, C. Tam-Amersdorfer, Q. Pan, T. Sconocchia, C. Pollack, B. Shaner, A. Zebisch, J. Easton, J. Yu, J. Silva, H. Strobl

This study identifies miR-424(322) as a molecular switch that controls the differentiation of pro-inflammatory monocyte-derived DCs (moDCs) versus anti-inflammatory Langerhans cells (LCs) by modulating TGF-β signaling.

bioRxiv · Sep 7, 2020 · PreprintImmunology

An automatic and efficient pulmonary nodule detection system based on multi-model ensemble

J. Chen, W. Wang, B. Ju, J. Jiang, L. Zhang, H. He, X. Zhang, Y. Shen

This paper presents a CAD system for pulmonary nodule detection that improves recall, reduces false positives, and optimizes time consumption using a multi-model ensemble approach.

bioRxiv · Apr 14, 2020 · PreprintBioengineering

Potent human neutralizing antibodies elicited by SARS-CoV-2 infection

B. Ju, Q. Zhang, X. Ge, R. Wang, J. Yu, S. Shan, B. Zhou, S. Song, X. Tang, J. Yu, J. Ge, J. Lan, J. Yuan, H. Wang, J. Zhao, , L. Zhang

This study isolates and characterizes 206 RBD-specific monoclonal antibodies from SARS-CoV-2 infected individuals, finding diverse neutralizing activity and species-specific antibody responses.

bioRxiv · Mar 21, 2020Immunology

Viral Architecture of SARS-CoV-2 with Post-Fusion Spike Revealed by Cryo-EM

C. Liu, Y. Yang, Y. Gao, C. Shen, B. Ju, C. Liu, X. Tang, J. Wei, X. Ma, W. Liu, S. Xu, Y. Liu, J. Yuan, J. Wu, Z. Liu, , L. Liu

The paper uses cryo-EM to reveal the post-fusion structure of SARS-CoV-2, showing the S protein in a state with S1 disassociated.

bioRxiv · Mar 2, 2020 · PreprintMicrobiology