J. Wang

This study shows invasive Zaprionus indianus populations have lower genetic diversity than native populations but maintain higher diversity than non-invasive species, and exhibit a broad thermal niche with no performance difference between invasive and native populations.

This paper identifies model organisms for studying ALK and LTK proto-oncogenes by analyzing their evolutionary history and ligand homology across species.

This study shows that cargo-free scaffolds recruit metastatic cancer cells through a lung-mimicking myeloid cell S100A8/A9 axis, reducing lung metastasis.

This study investigates changes in mechanical properties and nanomorphology of BMSCs during early apoptosis using AFM and other techniques, finding that mechanical damage precedes apoptotic signals.

The paper develops an in vitro model called Mipro that maintains gut microbiome functional and compositional profiles, showing strong correlation with in vivo responses to metformin.

The paper uses integrated proteomic and metabolic single-cell assays to identify two distinct adaptive pathways in BRAF-mutant melanoma cells during drug treatment.

This paper demonstrates that CRISPR-Cas9-assisted native end-joining editing can efficiently knock out large genomic regions in E. coli without exogenous repair systems.

The paper identifies deamidation at Asn-358 in moxetumomab pasudotox causing conformational changes and reduced immunotoxin activity.

The paper investigates the inverse relationship between fibronectin and neuroligins in the embryonic rat colon, showing direct regulation and negative correlation.

This study analyzes the vagino-cervical microbiome of 516 women using metagenomic shotgun sequencing to explore how pregnancy, delivery, and contraception influence microbiome composition.

The paper uses computational modeling to reveal a hydrophobic force-induced mechanism for pore formation in cholesterol-dependent cytolysins.

This study uses GaMD simulations to show that A1AR activation state affects its interaction with lipid bilayer, revealing coupled dynamics between the receptor and membrane.

This paper introduces CLEAR-dPCR, a lossless and contamination-free digital PCR technology that improves accuracy and dynamic range compared to existing platforms.

The paper analyzes oral microbiome data from the Earth Microbiome Project to show its distinct composition, lower diversity, and environmental correlations.

The paper investigates 5-hydroxymethylcytosine (5hmC) as a potential biomarker for pancreatic cancer, showing distinct distributions in tumor and adjacent tissues.

The paper identifies dysbiosis in RA tonsillar microbiota and shows that Streptococcus salivarius and its antibacterial peptides modulate autoimmunity by suppressing T cells and autoantibodies.

SPIKEPIPE accurately quantifies eukaryotic species abundances using DNA barcodes or mitogenomes with high accuracy and repeatability across environmental samples.

This study shows that engineering CAR-T cells with CD103 improves their anti-tumor efficacy against E-cadherin positive tumors by enhancing infiltration, expansion, and persistence in vivo.

PIRD is a database that collects and stores annotated TCR and BCR sequencing data, along with tools for visualization and analysis.

The paper examines 3D chromatin changes in T-ALL, identifies TAD fusion events linked to oncogene activation, and shows drug treatments can restore some interactions.

The paper uses MD simulations to study ligand transport by P-gp and shows lipids also play a role in this process.

This study identifies 28 dysregulated hepatic miRNAs in C57BL/6 mice infected with Echinococcus multilocularis eggs, showing downregulation of miRNAs involved in angiogenesis and fatty acid biosynthesis.

This study shows that calorie restriction leads to BMI loss in nonobese individuals, with variations linked to gut microbiota enterotypes.

This study identifies a comprehensive atlas of B-lymphocytes in triple-negative breast cancer using single-cell RNA-sequencing and antigen receptor profiling, revealing their mature characteristics and prognostic significance.

The paper performs single-cell RNA sequencing on TNBC tumors to identify novel immune cell subsets and their associations with survival and TCR signaling.

This study evaluates how golden apple snail residues affect soil properties and bacterial communities, finding that they increase soil nutrients and alter bacterial diversity and composition.

This study shows that microbiota community structure across various host organisms aligns with neutral model predictions, suggesting neutral processes rather than host selection primarily shape microbial communities after colonization.

The paper introduces tidyNano, an R package for analyzing nanoparticle data, and applies it to study murine placental extracellular vesicles across gestation and preterm birth.

The paper compares gut metagenomics and metaproteomics in prediabetics and treatment-naïve type 2 diabetics to identify host-microbial interplays across disease stages.

The paper identifies IL-24 as an anti-apoptotic factor in liver ER stress, showing its role in preventing cell death and its clinical relevance in acute liver failure.