J. Wang

This study uses single particle cryo-EM to determine the structure of 52 kDa streptavidin at 3.2 Angstrom resolution, demonstrating the feasibility of high-resolution imaging for small molecules.

The paper presents a MALDI-TOF MS method to detect ovarian cancer progression using vaginal fluid samples from tumor-bearing mice.

This study identifies adaptable retromer structures and their role in cargo sorting from endosomes to the TGN or plasma membrane in mammals.

The paper compares transcriptome profiles of maize CSSLs I178 and X178 under accelerated ageing to identify genes and alternative splicing events associated with seed longevity.

The paper creates a gene catalog of bovine rumen microbes, revealing high diversity and function in plant biomass degradation and methane production.

This study introduces E. faecalis strains into neonatal rats and finds that some strains increase necrotizing enterocolitis pathology.

This study characterizes the parasitic effect of Phanerochaete chrysosporium strain B-22 on Meloidogyne incognita life stages and demonstrates its efficacy as a biocontrol agent for tomato plants.

This paper reports the crystal structure of the HCMV UL144/BTLA complex, revealing molecular mechanisms of selective BTLA binding and informing the design of BTLA agonists.

This study identifies SKI-73 as a CARM1 chemical probe that reduces breast cancer cell invasion by altering epigenetic plasticity, distinct from CARM1 knockout effects.

This paper combines VAMS and mPlex-Flu assays to measure influenza antibody responses, showing high consistency between finger-stick and venous blood samples.

The paper investigates how eIF5B facilitates the transition from translation initiation to elongation in yeast using single-molecule fluorescence microscopy.

This study investigates RACK1's exchange dynamics on and off the ribosome using fluorescent labeling and biochemical analyses, showing its stable binding and limited conformational changes.

This study shows that Dickeya dadantii uses cell-length heterogeneity to balance virulence and growth during infection, with short cells being virulent and filamentous cells supporting rapid growth.

This study identifies genes regulating cell death in Staphylococcus aureus through a genome-wide screen, revealing both death-resistant and death-sensitive mutants with implications for virulence and antibiotic persistence.

This study identifies PRH1 as a target of ARF7 and LBDs in auxin signaling, showing its role in lateral root development through interaction with GATA23.

This paper demonstrates a gene therapy approach using NF-κB-activated CRISPR/Cas9 to specifically target and kill cancer cells without affecting normal cells.

This study develops a CRISPR-assistant trans enhancer to efficiently activate gene expression by combining dCas9-VP64/sgRNA with a CMV enhancer.

The paper improves in vitro culture conditions for Schistosoma mansoni, enabling sustained egg production and revealing male-induced female maturation and a novel nuclear receptor involved in sexual development.

This study designs a universal primer set for CAOB amoA genes and reveals their ubiquity and high abundance across diverse ecosystems.

This study shows that colonizing tsetse flies with Enterobacter inhibits trypanosome infection and reduces susceptibility to entomopathogenic bacteria without significant fitness costs.

This study reveals dynamic conformational landscapes of SETD8 using X-ray structures and molecular simulations, showing how protein dynamics influence catalysis and cancer-associated mutations.

The paper identifies 196 differentially expressed proteins in TGF-β1-treated lung fibroblasts and finds that VLDLR and SDC2 are upregulated in silica-exposed lungs, with knockdown reducing collagen production.

This study shows that H3K9me3 prevents nucleosome deposition at euchromatic promoters, affecting gene expression in C. elegans.

This study whole genome sequences normal colorectal crypts to reveal mutational processes and driver mutations in morphologically normal tissue, showing neoplastic changes are pervasive.

This study identifies and analyzes DNA methyltransferase genes in cotton, showing their functional diversity and stress-specific expression patterns.

This study identifies Cyclin B3's specific role in facilitating metaphase-to-anaphase transition in mouse oocyte meiosis I, while showing it is not required for oocyte maturation or sister chromosome segregation.

This study examines the sterilization effects of cavitation-shock interactions on marine Vibrio sp. through experimental and modeling approaches.

This study develops a fluorescent probe to measure glutathione concentrations in the nucleus and cytosol, finding no significant concentration gradient between them.

This paper introduces a tumor-specific causal inference framework to identify causative somatic genome alterations and their impact on molecular phenotypes in individual tumors.