L. Liu

The paper shows that nuclear positioning before asymmetric division is essential for correct division plane specification in maize stomatal development.

This study derives a theoretical framework for co-segregation probability from genome architecture mapping and shows that normalization with many nuclear slices improves correlation with inter-locus distances.

This paper introduces CP-seq, a method to test thousands of drug combinations on single cells using microwell-based droplet random pairing and single-cell RNA sequencing.

This study shows that Tfh17 cells are more effective than Tfh1 and Tfh2 cells in maintaining memory responses after vaccination.

This study characterizes the antigenic properties of the SARS-CoV-2 Omicron subvariant BA.2.75, showing increased neutralization resistance to vaccinated sera and specific monoclonal antibodies.

The paper identifies ID1 as an autonomous phosphate regulator that modulates the miR399-ZmPHO2 signaling module to maintain Pi homeostasis in maize.

The paper identifies a DPP4 homolog in Bacteroides thetaiotaomicron important for envelope integrity and fitness, showing it is inhibited by diabetes drugs.

This study identifies βγ-CAT as a pore-forming protein that enables cells to scavenge extracellular proteins under starvation by promoting nutrient uptake and survival.

This study shows that asparagine restriction induces a biphasic response in CD8 T cells, enhancing their metabolic fitness and antitumoral function through ATF4/NRF2-dependent mechanisms.

This study characterizes the enhanced infectivity and antibody evasion properties of the SARS-CoV-2 Omicron subvariant BA.2.75 compared to BA.5 and other variants.

The paper identifies genetic and regulatory mechanisms underlying heterosis in the rice hybrid Y900 by analyzing genome and transcriptome data from its parental lines.

This study shows that brassinosteroids promote tomato fruit ripening by enhancing ethylene production and carotenoid accumulation through the SlBZR1 transcription factor.

The paper shows restoring PITPNA in T2D human islets reverses beta-cell dysfunction by improving insulin granule maturation and glucose-stimulated insulin secretion.

This study identifies RNA binding proteins essential for leukemic stem cell survival using an in vivo CRISPR screen and highlights ELAVL1 as a therapeutic target in AML.

This study shows that Gre factors resolve transcriptional pauses in metabolic genes, enhancing Salmonella's antioxidant defenses against host phagocyte NADPH oxidase.

The paper shows that TIN1, an ER stress-induced protein in Arabidopsis, is selectively degraded by the ERAD complex during stress recovery, while other UPR-induced proteins remain stable.

This study identifies MLO4 as a Ca2+ channel essential for mechanosensing in Arabidopsis root tips, linking touch stimulation to Ca2+ elevation.

The paper develops PxR3D-map to predict and characterize photo-crosslinking in protein-RNA complexes using structural data and crosslink site mapping.

The paper identifies miRNA targets in maize using PARE datasets, revealing tissue-specific cleavage and new miRNA-target pairs involved in seed germination.

This study analyzes antibody evasion by SARS-CoV-2 Omicron subvariants BA.2.12.1, BA.4, and BA.5, finding BA.4/5 shows greater resistance to neutralizing antibodies than BA.2.12.1.

This study reveals a bimodal pattern of Piezo1-mediated intracellular calcium and FAK signaling, dependent on the degree of Piezo1 activation.

This study identifies Slamf9+Spp1+ macrophages in hamsters that promote SARS-CoV-2 clearance and inflammation resolution through spatial transcriptomics and scRNA-seq.

This study develops Stereo-seq, a high-resolution spatial transcriptomic method, to analyze mouse organogenesis and map developmental disease loci.

This study compares two iPSC-derived smooth muscle cell models, showing differences in proliferation, gene expression, and chromatin variants linked to arterial diseases.

This study shows that aligned electrospinning membranes with 319 nm diameter enhance skin wound healing by promoting epithelialization and macrophage transformation through IL10 and TGFβ expression.

This study shows that succinate dehydrogenase/complex II is essential for T cell proliferation and inflammation by regulating metabolic flux and epigenetic modifications.

This paper reports a synthetic nanobody, C5G2, that neutralizes SARS-CoV-2 and Omicron variants with high potency through a unique binding mechanism.

The paper identifies a pathway for breaking down plant N-glycans in gut Bacteroides and characterizes enzymes involved, with potential applications in allergen modification and therapeutic protein stability.

The paper designs proton-conducting channels that use transient water wires to achieve high selectivity for protons over sodium ions.

This study shows that adaptive immune cells around biomaterials promote hair follicle regeneration by activating fibroblasts, highlighting their role in wound healing.