L. Wang

The paper identifies Lnc956 as a non-coding RNA that forms a complex with TRIM28 and HSP90B1 to prevent replication fork collapse and maintain genomic stability in mouse embryonic stem cells.

The paper shows that sequential reperfusion with high CO2 then normal CO2 reduces cardiac ischemic reperfusion injury in rat hearts by altering metabolic pathways.

This study shows that Pseudomonas aeruginosa responds to surface stiffness through mechanosensing, affecting signaling, growth, and biofilm formation.

This study uses single-cell RNA sequencing to identify novel subtypes and intratumoral heterogeneity in olfactory neuroblastoma.

The paper identifies the T813S mutation in the S2 subunit of SARS-CoV Spike protein enhances fusogenicity by improving TMPRSS2 cleavage, increasing viral replication.

The paper identifies immature maize leaves as the primary organs for sensing herbivory-induced volatiles, showing reduced responsiveness in older leaves.

This paper reports the crystal and cryo-EM structures of GlnR-DNA and GlnR-TAC complexes, revealing the transcription activation mechanism of GlnR in actinobacteria.

This study creates a CD36 humanized mouse model to evaluate CD36-targeting therapies, showing that anti-CD36 antibodies inhibit tumor growth.

This study evaluates the neutralizing antibody response to bivalent mRNA vaccines against multiple Omicron variants, showing enhanced neutralization against BQ.1 and BQ.1.1.

The paper identifies KARS as mediating intra-translational deposition of N6-acetyl-L-lysine in nascent proteins, contributing to the acetylome in mice.

This study develops TAG72-CAR T cells with antigen-dependent IL-12 signaling to enhance anti-tumor activity and systemic disease targeting in ovarian cancer.

This study identifies leafhoppers as vectors for SoSGV, a virus associated with soybean stay-green syndrome, and shows they can transmit the virus to legume plants.

This study examines TE load variation in Arabidopsis during range expansion, finding increased TE load with expansion and identifying effective population size and transposition rates as key factors.

The paper sequences and assembles the nuclear and mitochondrial genomes of Bipolaris sorokiniana strain LK93 to improve understanding of its interaction with wheat.

This study identifies XBB as a SARS-CoV-2 variant resulting from recombination of BA.2 subvariants, showing increased resistance to neutralizing antibodies and enhanced fusogenicity compared to BA.2.75.

This study determines the structures of human ABCC4 in apo and complexed forms, revealing its role in exporting platelet agonists and inhibitors, and identifying a pocket for drug design.

The paper identifies a Switch-Helix in eIF2B that allosterically regulates ISR signaling and is conserved across species.

This study shows that SA, JA, and ET act in distinct spatial zones in Arabidopsis root cells during infection by Fusarium oxysporum, with SA inducing cell death and JA initiating defense.

The paper introduces pGG-PIP, a collection of GreenGate vectors with plant immune system promoters, enabling rapid construction of expression vectors for studying plant immunity.

This study shows that continuous hypoxia rescues retinal ganglion cell degeneration in a mouse model of mitochondrial optic neuropathy, though the effect is not sustained at later time points.

This study shows that TET2 mutations cause DNA damage, activating the cGAS-STING pathway, which drives clonal hematopoiesis and leukemia, and that STING inhibition can suppress these effects in mouse and patient models.

The paper generates and indexes an EMS mutant library for KN9204 wheat to enhance functional genomics and genetic manipulation for agronomic traits.

The paper identifies SAYSD1 as a sensor of ribosome UFMylation that facilitates TAQC by interacting with the translocon and UFM1 to degrade stalled proteins, maintaining ER homeostasis.

The paper investigates convergent evolution in SARS-CoV-2 Omicron subvariants, identifying five critical spike protein substitutions in BQ.1.1 that enhance viral fitness and antibody resistance.

This study develops DNA vaccines encoding chimeric RBDs of SARS-CoV and SARS-CoV-2 variants, showing potent immunogenicity and broad neutralization against multiple variants.

This study uses metabolomics to compare volatile metabolites across four Angelica species, identifying key compounds and phylogenetic correlations.

This study reports chromosome-level genome sequences of two Leonurus species, providing resources for studying bioactive molecules in medicinal plants.

This paper introduces an Odourgenetic method using Drosophila odorant receptors to non-invasively and rapidly manipulate cellular functions and behavior through inhalation of 2-pentanone.

This study shows that amyloid-beta peptides inhibit glucose transport at the blood-brain barrier by disrupting the insulin-Akt pathway and increasing TXNIP expression.

This study uses mid-infrared spectra of milk to establish models for assessing mammalian evolutionary relationships and genetic distances with high accuracy.