Y. Liu

The paper identifies ARMC2/PF27 as a specific cargo adapter required for IFT of radial spokes in Chlamydomonas, ensuring their assembly along flagella.

This paper introduces a novel COVID-19 vaccine based on a RBD-HR1/HR2 hexamer structure that induces high neutralizing antibody titers and alternative antibodies targeting the HR1 region in mice.

The paper investigates whether reaching and grasping kinematics are effector-independent by comparing hand and foot movements, finding shared ballistic phases but differences in deceleration and grip aperture timing.

This study evaluates HELP gels as injectable carriers to improve cargo retention in the myocardium, showing better retention than Matrigel in rat models.

This study shows that endophilin's curvature-sensitive motif requires electrostatic guidance for synaptic vesicle recycling, and that altering this property can restore function in non-functional chimeras.

This study shows that nutrient enrichment increases biomass and reduces anti-herbivory defenses in invasive plants, giving them a competitive advantage over native species.

This study shows pVHL regulates TCF/LEF protein stability via ubiquitin-independent proteasomal degradation, revealing a novel mechanism in Wnt/β-catenin signaling.

This paper introduces EVER, a method to improve super-resolution microscopy by recovering distorted emitters in heterogeneous backgrounds, enhancing image quality without manual parameter adjustment.

This study shows that modifying the Spo0A gene in B. velezensis SQR9 improves plant growth promotion when combined with FZB42 in two-member consortia.

This paper models homing suppression gene drives in haplodiploid organisms and finds they can be effective despite challenges like resistance and reduced drive power compared to diploids.

This study shows SARS-CoV-2 Spike protein causes abnormal blood clots and thromboinflammation, which are neutralized by a fibrin-targeting antibody.

This study shows AMPK and UPR interact via a positive feedback loop in muscle cells exposed to palmitate, with AMPK agonists enhancing UPR gene expression.

This study identifies CsMYB4a as a multifunctional transcription factor that regulates the auxin signaling pathway and phenylpropane/lignin pathways in Camellia sinensis.

This paper develops a split-nCas9 system using intein-mediated reassembly for efficient base editing in plants.

This study uses single-cell RNA sequencing to show heat shock proteins promote BCC growth in response to WNT5A-mediated inflammatory signals from the tumor microenvironment.

This study identifies Prevotella histicola as a protective agent against estrogen-deficiency induced bone loss via the gut microbiota-bone axis in mice.

The paper functionally expresses and characterizes an unclassified-class GST from the Colorado potato beetle, showing its role in xenobiotic adaptation through enzyme activity and substrate interactions.

This study expresses the human ZIP4 zinc transporter in yeast to study its function and localization.

This study shows that in C. elegans, NPR-8 neurons regulate collagen gene expression to extend lifespan at warm temperatures.

This study evaluates the effectiveness of high-energy electron beam irradiation in deactivating SARS-CoV-2 surrogate virus PEDV under cold chain conditions.

This study shows SMC1A promotes gastric cancer progression by enhancing SNAI2-driven EMT, suggesting it as a therapeutic target.

The paper uses cryo-electron tomography to reveal the ultrastructure of ASC specks and gasdermin D pores in NLRP3-activated cells.

This study shows TRIM47 enhances endothelial activation and pulmonary inflammation by promoting K63-linked ubiquitination of TRAF2, leading to NF-κB and MAPK pathway activation.

This study identifies SLC25A39 as a mitochondrial glutathione importer and shows its role in cell proliferation and red blood cell development, with GSH availability regulating its abundance.

The paper assesses the neutralization ability of BNT162b2-elicited sera against SARS-CoV-2 variants, finding that all sera neutralize variants to titers of ≥80, indicating vaccine effectiveness against emerging strains.

The paper uses computational methods to predict miRNA-target regulatory modules in soybeans under abiotic stress and identifies stress-related modules with gene ontology enrichment.

This paper introduces CARM, a CRISPR-Cas-based method for whole-genome mutagenesis, and demonstrates its application in evolving yeast strains for increased beta-carotene and S-adenosyl-L-methionine production.

This study identifies Lem8, a protease effector from Legionella pneumophila, which inhibits host cell motility by targeting Phldb2 via 14-3-3ζ-dependent activation.

This paper demonstrates that intranasal nanobody Nb22 provides short-term instantaneous prophylaxis and effective treatment against SARS-CoV-2 in hACE2 mice, with ultrahigh potency and long-lasting retention in the respiratory system.

This paper shows that CHD-1 and EFL-1/DPL-1 transcription factors reduce CDK-2 expression, which increases SAS-6 levels and centriole number in C. elegans embryos.