H. Yang

The paper introduces DPSN, a database that standardizes short names of amplicon-sequencing primers to reduce ambiguity and improve communication.

The paper creates a high-resolution global root biomass map using field measurements and environmental data, finding lower root biomass than previous studies due to improved methods and data.

The paper shows fibroblasts protect B. burgdorferi from a drug combination, but oregano or carvacrol essential oil enhances drug efficacy against the bacteria in fibroblasts.

The paper presents a large multi-omic cohort of 2,183 adults to identify correlations between gut microbiome features and various health-related factors, validated in an additional cohort.

The paper assembles over 56,000 metagenome-assembled genomes from oral microbiome samples, revealing new taxa and biomarkers for diseases.

This study identifies recurrent mutations and copy number variations as key drivers of metastasis in treatment-naive breast cancer using pre-clinical mouse models.

The paper uses historical and paleoecological data from Gatun Lake to study long-term impacts of damming and other stressors on tropical river ecosystems.

This study analyzes the vagino-cervical microbiome of 516 women using metagenomic shotgun sequencing to explore how pregnancy, delivery, and contraception influence microbiome composition.

This study shows BRD2 and SREBP2 work together to increase sigma-2 receptor expression when cells lack cytosolic cholesterol.

The paper estimates that 57% of mammalian genes are under purifying selection for stop codon preference, with UGA codons being more conserved and associated with specific gene characteristics.

PIRD is a database that collects and stores annotated TCR and BCR sequencing data, along with tools for visualization and analysis.

This study develops an efficient CRISPR/Cas9 method for integrating a large transgene cassette into the CEP112 locus in pigs, achieving successful expression of microbial enzymes in salivary glands.

This paper demonstrates that expressing eight immunomodulatory genes in mouse embryonic stem cells enables them to avoid immune rejection and form immune-privileged tissues in allogeneic hosts.

The paper shows that 3D matrix stiffness and dimensionality influence the expansion of hematopoietic stem and progenitor cells in vitro, affecting lineage fractions and gene expression.

This study identifies TMEM16F as a phospholipid scramblase essential for trophoblast fusion and placental development by externalizing phosphatidylserine.

This study shows that calorie restriction leads to BMI loss in nonobese individuals, with variations linked to gut microbiota enterotypes.

The paper performs single-cell RNA sequencing on TNBC tumors to identify novel immune cell subsets and their associations with survival and TCR signaling.

The paper identifies CHET3, a selective TASK-3 activator, and demonstrates its analgesic effects in pain models, highlighting TASK-3 as a novel non-opioid analgesic target.

The paper compares gut metagenomics and metaproteomics in prediabetics and treatment-naïve type 2 diabetics to identify host-microbial interplays across disease stages.

The paper analyzes gene panel sequencing data from 829 Chinese high-risk breast cancer patients to identify pathogenic variants and variants of uncertain significance across 115 hereditary cancer susceptibility genes.

The paper creates a gene catalog of bovine rumen microbes, revealing high diversity and function in plant biomass degradation and methane production.

This study examines how varying forage-to-concentrate ratios in sheep diets affect rumen bacterial structure, nutrient levels, and methane production, identifying key bacterial genera correlated with these factors.

This paper shows that HDAC3 inhibitors reverse CREBBP mutation-driven epigenetic changes in lymphoma, inhibiting tumor growth and restoring immune surveillance.

The paper constructs machine-learning models to predict influenza A virus serotypes using codon usage patterns from hemagglutinin and neuraminidase genes.

The paper describes modifications to the Illumina HiSeq 2500 platform for higher throughput amplicon sequencing with improved quality and multiplexing capabilities.

The paper identifies Dnmt3aos as a lncRNA regulating Dnmt3a expression and DNA methylation in macrophage polarization, revealing its role in modulating IFN-gamma expression.

This paper analyzes college students' risk perception of pandemic influenza in Beijing using mental model interviews and the Delphi method to identify key risk factors and improve risk communication strategies.

The paper compares transcriptomes of normal and dwarf soybeans to identify differentially expressed genes related to stress, defense, and growth.

This study generates transgenic pigs expressing microbial enzymes to enhance feed digestion and reduce nutrient emissions, showing improved growth and lower environmental impact.

This study analyzes TCRB and IGH repertoires in IgAN patients to identify non-invasive biomarkers for diagnosis.