S. Liu

This study uses spatial transcriptomics to analyze invasive fronts in solid tumors, identifying immune cell enrichment, metabolic changes, and poor prognosis factors.

This study identifies Lin28a's role in rejuvenating muscle stem cells through mitochondrial optimization and epigenetic regulation, enhancing their regenerative capacity.

This study identifies a β-catenin-NFκB-CFTR interactome in cholangiocytes that regulates inflammation and fibrosis during ductular reaction in liver disease.

The paper describes eight novel bacterial species isolated from cynomolgus monkey feces and provides their taxonomic characterization.

This study shows hyposalinity stress and Vibrio infection synergistically cause oyster mortality by disrupting microbial balance and triggering immune dysregulation.

This study investigates how the MIDAS domain of Mdn1 forms catch bonds with two different UBL substrates under force, revealing force-dependent binding lifetime changes.

The paper establishes a bacterial genome and culture collection of the piglet gut microbiome, revealing new species and functional insights.

This study shows that the yeast origin recognition complex can bind nucleosomes and license replication origins without requiring a consensus DNA sequence, suggesting this mechanism is conserved across eukaryotes.

The paper predicts conserved T-cell epitopes in SARS-CoV-2 variants using computational methods to identify antigenic peptides that could be used in vaccines.

This study uses a novel mouse model to show that spontaneous metastases in synchronous bilateral breast cancer originate from both primary tumors, revealing high cross-seeding of metastatic cells.

This study identifies R2R3-MYB transcription factors in C. sinensis and links some to the regulation of galloylated catechin biosynthesis.

The paper determines the structure of infective Getah virus at 2.8 Å resolution using cryo-EM, revealing glycosylation, S-acylation sites, and lipid interactions critical for immune evasion and host cell invasion.

The paper investigates how Geobacter metallireducens nanowires affect electron transfer efficiency in microbial fuel cells, finding increased voltage and electrochemical activity without the electron mediator AQDS.

This study identifies a major QTL on chromosome A09 associated with water-use efficiency and seed yield in Brassica napus, linked to homoeologous exchanges and gene expression differences.

This study shows SAFA interacts with antiviral RNAs to open chromatin and enhance immune gene expression during viral infection.

This study identifies multiple triggering factors for mutation repair in RNA viruses and shows that cell-to-cell movement enhances mutation repair, opposing the Muller ratchet effect.

This paper designs a trimeric RBD vaccine candidate with mutations from multiple SARS-CoV-2 strains, showing broad neutralization against variants including Beta and Kappa.

The paper uses in vivo cellular-level imaging to phenotype tumor-immune microenvironments, identifying distinct inflammation and endothelial anergy signatures linked to immunotherapy response.

This paper introduces ML-DBSCAN, a hierarchical clustering method for MD simulations, which identifies metastable states and free energy landscapes at multiple resolutions.

This study shows H. pylori has spread repeatedly from Africa by replacing strains with deleterious mutations through migration and selection.

The paper identifies the proteome of actin stress fibers in human fibroblasts and shows that eEF2 is upregulated with replicative senescence, contributing to SF reinforcement.

This study introduces terahertz wave modulation to enhance hearing perception in animals by increasing cochlear hair cell currents and sensitivity without genetic modification.

This paper develops a deep-learning enhanced on-chip DSLM system for high-speed volumetric imaging of neural activity in moving Drosophila larvae.

This paper introduces LCTC, a method to quantify structural distributions in heterogeneous cryo-EM datasets, showing improved performance over existing methods on simulated and experimental data.

This study shows that H2A ubiquitination is essential for PRC1 function and H3K27me3 deposition in Marchantia polymorpha, affecting gene and transposable element regulation.

The paper shows that PRC2/PRC1-mediated mitochondrial checkpoint regulates quiescence in Drosophila GSCs and human iPSCs through mitophagy and mitochondrial dynamics.

This study shows that the B.1.1.7 SARS-CoV-2 variant replicates and sheds more efficiently in hamsters' nasal cavities than earlier D614G variants with lower doses and shorter exposure.

This study evaluates antibiotic concentrations affecting gut bacteria and Ectropis obliqua growth, finding 300g/ml effectively clears bacteria without harming growth.

This study constructs two oncolytic adenoviruses carrying mK5 or MnSOD genes under survivin promoter control and shows their combined use significantly inhibits gastric cancer growth in vitro and in vivo.