W. Liu

The paper reports that a Chlamydia strain from SARS patient autopsy samples inhibits SARS-CoV proliferation in vitro, with inhibitory factors present in both extracellular and intracellular cultures.

This study shows that OsLEC1 inhibits photosynthesis in rice embryos to promote seed dormancy by regulating hormonal pathways and gene networks.

The paper examines S. commune fruiting bodies and hyphae to confirm the presence of calcium oxalate crystallites, demonstrating biomineralization in this fungus.

This study identifies how monocot DCL3 and DCL5 proteins evolved distinct substrate specificities through mutations in their PAZ domains, leading to specialized siRNA production.

This study shows FANCD2 inhibits DNA2 nuclease activity and stabilizes RAD51 filaments to protect stalled replication forks, promoting genome stability.

This study shows that the moss CLAVATA pathway modulates auxin homeostasis and transport to control stem cell identity and plant shape, suggesting this mechanism is conserved in land plants.

This paper demonstrates a genotype-independent in vivo haploid induction system in dicot crops by mutating DMP genes, achieving HI rates of 1.9%, 2.4%, and 1.2% in tomato, rapeseed, and tobacco respectively.

This study shows TMEM120A does not mediate poking- or stretch-induced currents and identifies a specific coenzyme A-binding site through cryo-EM structures.

The paper determines HVEM structures and generates mutants to reveal distinct functions of binding to LIGHT and BTLA/CD160 in immune responses.

This study identifies m5C mRNA modifications mediated by Plasmodium NSUN2 as critical for transcript stability and gametocyte development in malaria parasites.

This study shows a single-dose AAV-based vaccine induces long-lasting neutralizing antibodies against multiple SARS-CoV-2 variants in rhesus macaques.

This study identifies a maize inbred line, Xi502, that mounts effective defense against fall armyworm, showing distinct transcriptomic and elicitation responses compared to the susceptible line B73.

The paper shows that environmental selection overrides the distance-decay pattern in soil prokaryotic communities across biomes, revealing a U-shape pattern due to homogeneous environmental factors.

This study uses optical tweezers and molecular dynamics to analyze the mechanical unfolding kinetics of yeast tRNAphe, revealing how structural features influence folding and the role of tertiary interactions in unfolding cooperativity.

This study investigates age-dependent and -independent immune responses to a vaccine against Teladorsagia circumcincta in lambs, showing that younger lambs are more susceptible to infection despite vaccination.

This study shows that tonic interferon signaling maintains immune homeostasis by regulating gut microbiota, preventing IL-17-driven inflammation and myeloid hyperplasia in STAT1 KO mice.

The paper examines the relationship between mangrove forest fragmentation and salt marsh invasion magnitude across a climatic gradient in southeast China.

This study identifies IDH2 as a targetable regulator of drug resistance in CML by analyzing proteomic changes in resistant K562 cells.

This study identifies DDX21 cleavage by caspase-3/6 during virus infection as a mechanism to suppress IFN-β signaling by disrupting the DDX1-DDX21-DHX36 complex.

This study develops a trimeric RBD vaccine that induces long-term immunity and complete protection against SARS-CoV-2 in nonhuman primates.

This study uses fMOST and scRNA-seq to map the spatial and cellular distribution of rabies virus in the mouse brain, revealing infection in multiple nuclei and non-neuronal cells.

This study uses single-molecule FRET to show that NF-κB exhibits a continuum of binding modes that control its association and dissociation from DNA, with IκB modulating these dynamics.

This study shows that IBV uses nsp15 to inhibit stress granule formation, thereby evading antiviral responses and promoting viral replication.

This study uses live-cell imaging to show Hfq dynamically interacts with mRNAs and sRNAs, recruiting RNase E to promote mRNA turnover and enabling sRNA-mediated gene regulation.

The paper assembles a chromosome-scale, allele-aware autotetraploid genome of alfalfa cultivar Zhongmu-4 and identifies 101 SNPs associated with 27 agronomic traits using GWAS.

This study inhibits multi-species biofilm formation by targeting cellular metabolism with three metabolic inhibitors, showing enhanced efficacy when used together.

This study analyzes the evolutionary patterns of ACE2 binding affinity to SARS-CoV-2 spike protein across 247 vertebrates and identifies key amino acid mutations driving affinity divergence.

This study engineers 'spark-cell' spheroids to enable optical pacing of cardiac tissue, showing they can stimulate human stem-cell-derived cardiomyocytes faster than direct genetic modification.

This study shows Ythdc1, an m6A reader, regulates LINE1 scaffold function in mouse ESCs, affecting self-renewal and differentiation through chromatin interactions.

This study shows that Newcastle disease virus induces ferroptosis in tumor cells via the p53-SLC7A11-GPX4 pathway, leading to nutrient deprivation and cell death.