X. Zhao

This study sequenced the genome of water wisteria, revealing genes and pathways involved in its environmental adaptation and leaf shape changes.

The paper introduces a chemoenzymatic method to detect cell-surface glycan in single-cell multiomics, showing increased LacNAc in activated CD8+ T cells and its correlation with glycolytic activity.

The paper maps AP complex interactions in Arabidopsis, identifying P34 as a stability regulator of clathrin-mediated endocytosis and post-Golgi trafficking.

This study evaluates neutralization of Omicron sub-lineages by booster vaccination or BA.2 breakthrough infection sera using a pseudovirus panel.

This study identifies EFNA4 amplification as a driver of lung adenocarcinoma lymph node metastasis through genomic analysis and functional experiments.

This paper develops equine polyclonal antibodies that broadly neutralize major SARS-CoV-2 variants, showing high efficacy in vitro and ex vivo with low cost and potential for large-scale production.

This study shows that overexpressing connexin43 in bone marrow-derived stromal stem cells promotes osteogenesis and angiogenesis, enhancing bone regeneration in a rat model of glucocorticoid-induced osteonecrosis.

This study shows that SARS-CoV-1 survivors vaccinated with ZF2001 have reduced neutralization against SARS-CoV-2 Omicron compared to other variants.

This paper develops an ultra-small bispecific fusion protein, Bi-fp50, that improves tumor penetration and treatment efficacy for pancreatic cancer by targeting EGFR and VEGF.

This study uses cryo-electron tomography to reveal the asymmetric protein complexes in mammalian sperm axonemes, explaining their unique flagellar beating pattern.

This study shows that Nlrc4 inflammasome recognition of Salmonella flagellin is critical for mucosal immunity but not systemic infection.

This study analyzes the temporal transcriptome changes in porcine macrophages infected with different ASFV strains to understand viral pathogenicity and host response dynamics.

This study shows that IDOL deficiency reduces atherosclerosis in rabbits fed a high-cholesterol diet by improving lipid metabolism and bile acid excretion.

This study shows that aligned electrospinning membranes with 319 nm diameter enhance skin wound healing by promoting epithelialization and macrophage transformation through IL10 and TGFβ expression.

The paper uses organoid models to show that WNT2B promotes vascularization in pregnancies, linking trophoblast function to vascular development in both intrauterine and ectopic pregnancies.

This study quantifies neoantigen-mediated immunoediting stages in cancer evolution across tumor types, showing elimination and escape signals predict immunotherapy response.

This study compares antibody neutralization efficacy against SARS-CoV-2 Omicron sub-lineages BA.1, BA.1.1, BA.2, and BA.3, showing increased resistance and the benefit of vaccine boosters.

This study develops geometrically-inverted proximal tubule organoids to better model proteinuric kidney disease by enabling apical surface access for protein uptake studies.

The paper identifies KEA3 as the main regulator of the PET/PMF relationship in diatoms, showing its role in modulating NPQ responses and light acclimation.

This study shows Rtt105 binds to RPA, staples it, and blocks RIP interactions without ssDNA, while stabilizing RPA-ssDNA filaments with ssDNA.

This study shows that extrachromosomal DNA (ecDNA) is linked to reduced immune cell infiltration and antigen presentation, suggesting it helps cancer cells evade immune surveillance.

This study uses single-cell RNA sequencing to identify five MSC subpopulations, revealing distinct developmental trajectories and functional roles in self-renewal and immunoregulation.

This paper develops a bi-continuous conducting polymer hydrogel with high electrical conductivity, stretchability, and fracture toughness for 3D printable bioelectronics.

This study identifies FOXM1 as a transcription factor that specifies and loads chromatin DNA fragments into extracellular vesicles via an LC3-dependent autophagosome-MVB pathway.

The paper investigates how marine bacteria respond to opposing chemotactic signals from crude oil components using a mathematical model.

The paper identifies ASGR1 as a potential receptor for SARS-CoV-2 that facilitates liver cell infection and suggests soluble ASGR1 as a therapeutic target.

The paper develops a method using engineered nanoparticles to enhance plasma proteome coverage by optimizing protein-NP interactions and competition, resulting in deeper and more consistent proteomic profiling.

This study uses a multiscale model to predict E. coli migration in response to competing chemoeffectors, showing direction is controlled by relative concentrations.

This study shows that homologous or heterologous boosters of inactivated vaccines increase neutralizing antibodies against SARS-CoV-2 Omicron, reducing escape from neutralization.

The paper tests neutralization activity of sera from convalescents and vaccine recipients against Omicron, finding that vaccines maintain better neutralization than convalescents.