Z. Zhao

This study compares thermal stress responses and transcriptomic profiles of different shell colour morphs in the snail Batillaria attramentaria, finding that dark morphs exhibit preparative defense strategies and higher cardiac thermal tolerance.

The paper identifies intratumoral niches involving mregDC and CXCL13+ Th cells that support CD8 T cell differentiation following PD-1 blockade in HCC patients.

This study investigates the effects of FABP1 and FAS overexpression on collagen III and cross-linking in Zongdihua pig tissues, identifying their roles in fat deposition.

This study investigates how protein condensates interact with membranes, leading to morphological changes and introduces a theoretical framework to describe these interactions.

This study identifies a necroptosis-related gene signature (NRGscore) to predict prognosis and therapeutic response in bladder cancer patients using TCGA data.

This study identifies bZIP25 and bZIP53 as transcription factors regulating pavement and trichome cell development in Arabidopsis thaliana using single-cell RNA-sequencing.

This paper introduces Nano2RED, a rapid, affordable diagnostic platform using nanobody-functionalized nanoparticles to detect viral antigens with high sensitivity and speed.

This study investigates how hydrostatic pressure affects deep-sea microbial carbon cycling, finding that piezophilic and piezotolerant prokaryotes dominate, while piezosensitive bacteria show increased activity under reduced pressure.

This study maps single-cell transcriptomes and T cell repertoires in Behcet's disease to identify immune mechanisms and T cell trajectories in vascular and dermal manifestations.

This study identifies POU2AF2 as a co-activator of POU2F3 in SCLC, showing it maintains chromatin accessibility and enhancer activity essential for tuft cell marker expression.

This paper introduces DeepCAD-RT, a real-time denoising method for fluorescence time-lapse imaging that improves signal-to-noise ratio with fewer photons, demonstrated across multiple organisms and biological processes.

The paper develops a method using peptidiscs and proteomics to stabilize and identify detergent-sensitive membrane protein complexes, demonstrating its effectiveness with the E. coli Sec system.

The paper describes the purification of a viral reference database (EVRD) by removing contaminating sequences, improving accuracy and efficiency in viromic analysis.

This study identifies functional determinants of Tae1, a bacterial T6SS amidase toxin, showing that its antimicrobial potency depends on substrate topology and cellular context.

The paper identifies sustained epigenomic changes in hematopoietic stem and progenitor cells after COVID-19, which influence innate immune cell function and inflammation.

This study investigates how feed-borne bacteria affect gut microbiota in farmed juvenile Takifugu obscurus, showing that slower growth is linked to greater microbiota instability and increased feed source influence.

This study identifies shifts in lung macrophage composition linked to COVID-19 severity and recovery, suggesting therapeutic strategies targeting macrophage function.

The paper tracks cyanopeptides and their impact on microbiota during a CyanoHAB, finding that cyanopeptide restriction and degradation drive community assembly.

This study identifies CD73 as a key driver of immunosuppression in pancreatic ductal adenocarcinoma, showing its role in adenosine generation and tumor progression.

This study identifies microbial communities and genes potentially involved in the degradation of low-density polyethylene (LDPE) in the ocean using metagenomics and long-term incubation experiments.

This study shows that G6PD deficiency in melanoma cells increases oxidative stress and glutaminolysis, reducing metastasis by making cells more vulnerable to metabolic disruption.

This study shows that humanized mice can be infected by SARS-CoV-2, leading to immune responses and immunopathology, providing a model for studying the virus and testing therapies.

The paper identifies two distinct ER tubule forms, R1 and R2, regulated by Rtn4 and Climp63, with functional implications for ER structure and dynamics.

This study shows that Zika virus causes placental pyroptosis via GSDME activation, leading to adverse fetal outcomes.

The paper evaluates 887 PCRP antibodies against human transcription factors using ChIP-exo and other assays, identifying 5% as strong candidates and 34% as warranting further testing.

The paper identifies a role for the clathrin-mediated endocytic machinery in maintaining synaptic EV cargo pools, distinct from its canonical functions in synaptic vesicle recycling.

This study uses super-resolution microscopy to image highly curved membrane structures in synthetic cells, revealing membrane properties and their agreement with theoretical predictions.

This study identifies {beta}{gamma}-CAT as a secretory pore-forming protein that drives macropinocytosis and exosome release to aid water uptake in toads under hypertonic stress.

This study shows AK2 deficiency disrupts mitochondrial metabolism, causing purine metabolism disorder and myelopoiesis failure through AMP accumulation and NAD+ depletion.