Q. Wang

This study identifies Notopterol as a JAK2/3 inhibitor that reduces inflammation and arthritis by blocking macrophage cytokine production in animal models.

This study shows SPOP promotes ubiquitination and degradation of MyD88, suppressing innate immune responses and reducing susceptibility to Salmonella typhimurium infection.

This study shows HIV-1 Vpr suppresses IRF7 and IFN-I expression in pDCs by degrading TET2, thereby enhancing HIV-1 replication.

This study identifies Msi1+ cells as rapidly cycling intestinal stem cells that regenerate the intestine independently of Lgr5high cells.

The paper identifies MRISC cells as a novel intestinal stem cell niche that produces R-spondin1 via Map3k2 signaling to promote intestinal regeneration after damage.

This study develops a serum-free method to generate human mesenchymal stem cell spheroids using knockout serum replacement, showing similar transcriptomes to FBS-based spheroids and retained MSC markers.

This study identifies 26 gut microbiome biomarkers associated with schizophrenia and links specific bacterial species, like Streptococcus vestibularis, to altered neurotransmitter levels and behavioral changes in mice.

This study identifies GATA3 and AP1-driven enhancer reprogramming as a mechanism promoting phenotypic plasticity and endocrine resistance in breast cancer.

This study shows CaMKII oxidation by ROS evolved in vertebrates to enhance performance but increased disease risk.

This paper establishes a novel human HCC patient-derived xenograft model in immunocompetent mice, showing high tumor formation rates and preserved tumor characteristics.

This study uses single-cell profiling to identify immunosuppressive cells in CDK4/6 inhibitor-resistant HER2+ breast cancer and shows that combinatorial immunotherapy can overcome resistance.

This study identifies YAP1 as a context-specific driver for the squamous subtype of pancreatic ductal adenocarcinoma and shows WNT5A promotes tumor progression through YAP1 activation.

This study introduces a dual scintillator configuration for radioluminescence microscopy, doubling sensitivity and halving image acquisition time for short-lived radiotracers.

This paper demonstrates that GXMR-CAR+ T cells can effectively target and reduce Cryptococcus neoformans burden in a murine model.

This study compares biodegradable mulch film with polyethylene plastic film in cotton and maize, finding higher yield and water use efficiency with biodegradable film without residual pollution.

The paper investigates positive selection for mRNA secondary structure at synonymous sites in domesticated yeast, finding that GC content and structure influence translational efficiency and adaptation.

This study compares the efficacy of new bio-pesticides and conventional chemical pesticides against Tetranychus cinnabarinus, finding abamectin to be the most effective.

This study investigates the DNA damage response in mouse peripheral blood leukocytes after variable, low-dose rate 137Cs exposure using a novel irradiation device, finding that γ-H2AX levels correlate with accumulated dose and could serve as a biomarker for radiation dosimetry.

This study shows that LSD1, recruited by Blimp-1, represses PD-1 expression during acute infection by removing activating histone marks and is necessary for remethylation of the Pdcd1 locus.

This study shows Toxoplasma gondii infection converts NK cells into ILC1-like cells that persist and circulate independently of infection.

The paper develops a high-throughput γ-H2AX assay using imaging flow cytometry to measure DNA double-strand break repair kinetics in human blood cells after ionizing irradiation.

This study identifies mutant p53's role in promoting clonal hematopoiesis by modulating the EZH2-mediated epigenetic pathway.

This study shows that miR-383 suppresses Bcl-2 translation, promoting apoptosis in gastric carcinoma cells during chemotherapy.

This study investigates lipid interactions of PC2 using simulations and cryo-EM, identifying PIP and cholesterol binding sites.

This study compares bacterial composition and functional differences between cancerous and noncancerous ovarian tissues using 16S rRNA sequencing and metagenomic predictions.

This study combines Azospirillum brasilense inoculation with seed priming to enhance germination and seedling growth in aged grass seeds, finding that H2O2 priming with optimal bacterial concentration and time is most effective.

The paper identifies novel haplotypes and evolutionary pathways of AVR-Pik alleles in Magnaporthe oryzae using DNA sequence analysis and field-based avirulence testing.

This study identifies TMEM16K as an ER-resident calcium-regulated lipid scramblase and elucidates its structural basis for lipid scrambling and inactivation.

This study evaluates how different pretreatments affect flavonoid content and antioxidant activity in Dryopteris erythrosora leaves, finding that shade drying followed by oven drying best preserves these properties.