Y. Lu

This study identifies Reg4 as an antimicrobial peptide that combats Salmonella Typhimurium by binding flagellin and inhibiting bacterial motility, adhesion, and invasion.

This study characterizes global soil yeast diversity using culture-based methods and identifies environmental factors influencing their distribution.

Conditional Tfr1 ablation in satellite cells causes ferroptosis, leading to skeletal muscle regeneration defects and labile iron accumulation, recapitulated in aged rodents.

This study investigates the role of the origin of replication (Ori) in Thermococcus barophilus, showing its necessity for DNA replication and growth under varying temperatures.

This study investigates salt-induced structural transitions in the DNA-interacting protein SSB using magnetic tweezers and infrared spectroscopy, revealing discontinuous thermodynamic behavior at binding mode transitions.

This study identifies ZmLBD5 and ZmLBD33 as class II LBD genes in maize that regulate gibberellin and abscisic acid biosynthesis, affecting plant growth and drought tolerance.

This study identifies S6K2 as a vulnerability in MAPK inhibitor-resistant NRAS-mutant melanoma, showing its abrogation disrupts lipid homeostasis and triggers cell death.

This study shows SARS-CoV-2 infection in Syrian hamsters causes inflammation and type I interferon suppression in multiple organs, including the heart and kidney, similar to human COVID-19 symptoms.

This study shows that circadian-regulated endocytic recycling is essential for collagen fibril assembly and is disrupted in fibrosis.

This study identifies SSR1 as a chaperone-like protein that enhances HSCA2-ISU1 interaction in the mitochondrial iron-sulfur cluster biosynthesis pathway, essential for plant mitochondrial function.

This study demonstrates that enhanced biological phosphorus removal (EBPR) can be stable at 35°C in lab-scale reactors, with nearly complete phosphorus removal and diverse PAO communities.

This study identifies 35 FDA-approved drugs that reduce SARS-CoV-2 replication in human cells, including amodiaquine and vitamin D3.

The paper introduces a microchip called NOMA that enables sequential tracking of secretions from the same single cells with high retention efficiency.

This paper introduces MaAsLin 2, a method for analyzing multivariable associations in microbial multi-omics data, and applies it to reveal new insights into inflammatory bowel disease.

This study shows that bacteria in the rectum of male oriental fruit flies produce sex pheromones, specifically TMP and TTMP, which attract females.

This study uses label-free GLIM to quantify HIV reactivation in single cells by analyzing morphological changes, finding specific dry mass and diameter thresholds associated with latency and reactivation.

The paper develops a method to measure subnanometer position changes of biomolecules in live cell plasma membranes using extracellular quenchers and validates it by studying peptide-induced membrane perforation.

This paper demonstrates the first use of high-energy X-rays in FLASH radiotherapy, showing effective tumor control and tissue protection in mice.

This study shows that magnetite enables methanogens to adapt to higher cathode potentials in electrochemical reactors, enhancing electromethanogenesis.

This study identifies TFR1, SAHH, and HV307 as potential biomarkers for colorectal cancer screening through proteomics analysis of pre-cancerous to cancerous tissues.

The paper identifies a peroxidase inhibitor, 6D1, that enhances kanamycin activity against carbapenem-resistant bacteria.

The paper analyzes SARS-CoV-2 quasispecies structure using SMRT sequencing, revealing a One-King model with dominant and minor haplotypes and their evolutionary dynamics.

This paper identifies DDX50 as a viral restriction factor that enhances TRIF-dependent IRF3 activation, thereby restricting viral replication and dissemination.

This paper describes a catalase-based therapeutic for COVID-19 that reduces oxidative stress and cytokine production in human and animal models without toxicity.

The paper introduces a fast numerical method for simulating oxygen supply in tissue with complex blood vessel networks, achieving accurate results efficiently.

The paper shows that HIV-1 reactivation from latency is regulated by a transient heritable memory in T cells, revealed through fluctuation assays and mathematical modeling.

This study identifies potent human neutralizing antibodies against SARS-CoV-2 from convalescent patients, with some showing high efficacy in blocking viral entry.

This study evaluates the virucidal activity and safety of Povidone-iodine in-situ gel formulations against SARS-CoV-2 in vitro and in vivo.

The paper shows that lateral mechanical impedance, not frontal, promotes cortical expansion and radial growth in maize roots.