J. Zhang

This study uses cryo-electron tomography to reveal the high-resolution 3D structure of 293T cell membranes, showing lipid bilayer thickness and protein distribution.

The paper identifies BR-responsive gene expression in Arabidopsis root cells using single-cell RNA-sequencing and reveals HAT7 and GTL1 as transcription factors regulating cell elongation.

This study reconstructs the phylogeny of the hyperdiverse Chalcidoidea wasps, identifying classification issues and evolutionary shifts linked to angiosperm diversification.

This study identifies FOXA1 and Ku70/Ku80 as direct targets of ivermectin in prostate cancer, showing it induces cell cycle arrest, apoptosis, and synthetic lethality through chromatin accessibility reduction and DNA repair impairment.

This study shows that cardiomyocyte alpha-1A adrenergic receptors reduce post-infarct mortality and remodeling by limiting necroptosis, with clinical evidence linking beta-blocker use to increased MI mortality.

This paper designs optimized monophasic TMS pulses that reduce coil heating while maintaining neuromodulation effectiveness, enabling higher pulse rates.

This study identifies OPRIII genes in wheat that modulate root architecture and grain yield under water stress through jasmonic acid signaling.

This paper identifies LPD-3 as a conserved megaprotein critical for lipid trafficking between ER and PM, essential for cold resilience in C. elegans and other species.

The paper evaluates the fitness effects of synonymous mutations in yeast, refuting claims that they are largely neutral and showing they are often deleterious.

The paper introduces ELI-TriScope, a cryogenic system for precise cryo-lamella preparation, achieving 100% success in targeting HeLa cell centrosomes for cryo-ET structural analysis.

The paper develops a method to degrade ERBB2 mRNA and protein by destabilizing its 3UTR AU-rich elements, showing efficacy in drug-resistant cancer models.

SIC50 uses a vision transformer and Sobel operator to determine IC50 from phase-contrast images, validated with four drugs and 1536-well plates.

The paper identifies EaF82, a RALF-like peptide, which delays tapetum degeneration in Arabidopsis by reducing ATP levels through AKIN10 interaction, impairing pollen development.

This study identifies spike-specific CXCR3+ TFH cells as key drivers of long-term antibody responses in SARS-CoV-2 infection and vaccination.

This study identifies SlMAP70 as a regulator of tomato fruit shape by interacting with SlIQD21 and modulating microtubule organization during fruit development.

This study shows that the p73{gamma}-Leptin pathway promotes tumorigenesis and alters lipid metabolism by demonstrating that E11 deletion increases p73{gamma} and Leptin, leading to oncogenic effects in mice and human cancers.

This study shows that Srf reduces gene expression noise and stabilizes cell state in mouse pluripotent stem cells by limiting developmental heterogeneity.

This study shows low light stress reduces summer maize yield by decreasing leaf photosynthetic rate, impairing sucrose transport to grains, and creating a sugar concentration gradient that inhibits sucrose output.

The paper demonstrates that swim bladder resonance enhances hearing in crucian carp through auditory evoked potentials, Micro-CT, and numerical simulations.

This study examines the transcriptome response of Cannabis sativa to the pathogenic fungus Golovinomyces ambrosiae, identifying differentially expressed genes and potential defense mechanisms.

This study shows porcine STING has antiviral activity independent of IFN and autophagy, and also triggers apoptosis to resist viral infections.

The paper characterizes the genomic and transcriptomic landscape of MDA PCa PDX models and develops an organoid platform to study prostate cancer heterogeneity and resistance.

This paper identifies FcγRIIB-mediated capture of antibody-coated bacteria by liver sinusoidal endothelial cells as a mechanism for superior vaccine efficacy.

This study shows that asparagine restriction induces a biphasic response in CD8 T cells, enhancing their metabolic fitness and antitumoral function through ATF4/NRF2-dependent mechanisms.

The paper analyzes aging and cancer by profiling ubiquitinome and RNA-seq data in mice, identifying H2A ubiquitination as a marker linked to prognosis and tumor microenvironment.

The paper evaluates how different habitat compositions affect functional traits of arthropod communities in subtropical vegetable fields, finding that forest and grassland habitats enhance functional diversity while non-brassica plantations and water bodies reduce it.

This study identifies the OsNLP4-OsMADS27 module as a nitrate-dependent regulator of salt tolerance in rice, showing its role in stress response and yield improvement under salt stress.

This study investigates microRNA-mediated cross-kingdom regulation between Asian honey bee and microsporidian using RNA-seq and small RNA-seq data, identifying miRNA-target mRNA interactions and their roles in glycolysis, virulence, and immune response.

The paper visualizes limonene synthesis metabolons in engineered E. coli using hyperspectral SRS microscopy and confirms colocalization with limonene synthase.