Z. Bao

Internalisation of integrin-bound extracellular matrix modulates invasive carcinoma cell migration

This study identifies 2β1 integrin and MAP3K1/p38 signaling as regulators of ECM internalization, which promotes cancer cell migration and invasion in breast and pancreatic cancers.

Spiral NeuroString: High-Density Soft Bioelectronic Fibers for Multimodal Sensing and Stimulation

This paper introduces Spiral NeuroString, high-density soft bioelectronic fibers for multimodal sensing and stimulation, demonstrating their use in GI motility mapping, serotonin sensing, and brain recordings.

Topographical analysis of immune cell interactions reveals a biomechanical signature for immune cytolysis

The paper analyzes immune cell interactions using traction force microscopy to identify biomechanical features associated with cytotoxic T cell activity.

In situ genetically targeted chemical assembly of polymers on living neuronal membranes

The paper develops a method to genetically target polymer assembly on neuronal membranes to modify electrical properties with improved efficiency and biocompatibility.

Genetically-encoded photosensitizers enable light-controlled polymerization on living neuronal membranes

This paper introduces a method to control polymerization on living neuronal membranes using light-activated photosensitizers, enabling non-invasive modification of neural circuits.

Soft and stretchable organic bioelectronics for continuous intra-operative neurophysiological monitoring during microsurgery

This paper introduces a soft, stretchable organic bioelectronic system for continuous intra-operative neurophysiological monitoring during microsurgery, demonstrating improved signal quality and reduced post-operative complications in animal models.

The microtubule-associated protein SlMAP70 interacts with SlIQD21 and regulates fruit shape formation in tomato

This study identifies SlMAP70 as a regulator of tomato fruit shape by interacting with SlIQD21 and modulating microtubule organization during fruit development.

Topological supramolecular network enabled highly conductive and stretchable organic bioelectronics

This paper introduces a topological supramolecular network strategy to create highly conductive and stretchable organic bioelectronics with unprecedented performance in physiological environments.

Wireless closed-loop smart bandage for chronic wound management and accelerated tissue regeneration

This paper develops a wireless smart bandage that monitors wound conditions and delivers electrical stimulation to accelerate tissue regeneration in chronic wounds.

A flexible electronic strain sensor for the real-time monitoring of tumor regression

This paper introduces a flexible electronic strain sensor that continuously monitors tumor volume changes in real-time, validated in mouse models with lung cancer and B-cell lymphoma.

Design considerations of a wearable electronic-skin for mental health and wellness: balancing biosignals and human factors

The paper designs a wearable electronic-skin for mental health monitoring, finding that upper arm and forearm are optimal wear locations by balancing human factors and biosignal accuracy.

Species-resolved sequencing of low-biomass microbiomes by 2bRAD-M

This paper introduces 2bRAD-M, a low-cost metagenome-sequencing method that enables species-level microbial profiling of low-biomass and degraded samples with high accuracy.

Small RNAs couple embryonic developmental programs to gut microbes

This study shows that maternal gut microbes induce additional embryonic cell divisions in C. elegans through RNAi and miR-35, challenging the idea of an invariant cell lineage.

MGMT genomic rearrangements contribute to chemotherapy resistance in gliomas

This study shows that MGMT genomic rearrangements cause TMZ resistance in gliomas and can be detected in exosomes as potential recurrence markers.

ARHGEF3 regulates skeletal muscle regeneration and strength through autophagy

This study shows ARHGEF3 promotes muscle regeneration and strength by enhancing autophagy, independent of mTORC2-Akt signaling, in both young and aged mice.

Accelerating iterative deconvolution and multiview fusion by orders of magnitude

This paper introduces faster deconvolution and multiview fusion methods, achieving speedups of 10 to several thousand-fold over previous approaches.

The Histone Demethylase KDM4D Promotes Hepatic Fibrogenesis by Modulating Toll-Like Receptor 4 Signaling Pathway

This study identifies KDM4D as a key regulator of hepatic fibrosis by modulating TLR4 signaling through histone demethylation in HSCs.