Q. Liu

This study shows that mesenchymal stem cells (MSCs) reduce CAR-T cell effectiveness against lymphoma by altering the microenvironment via stanniocalcin-1.

The paper analyzes survey data from a virtual artist-in-residence program to compare experiences and outcomes between student-artists and faculty, identifying areas for improvement and benefits.

This study shows that initial niche conditions determine the aging speed and regenerative activity of quiescent fission yeast cells, with regenerative activity declining linearly before survivability.

This study identifies mce3R mutations causing contezolid resistance in Mycobacterium tuberculosis by increasing Rv1936-mediated drug degradation.

This study identifies biotin-dependent fatty acid remodeling as essential for Mycobacterium abscessus survival in the lung, suggesting biotin synthesis and fatty acid metabolism as therapeutic targets.

This study quantitatively maps yeast cell fate decisions in response to pheromone by integrating experimental observations with theoretical models and stochastic simulations.

This study generates genetically engineered goats expressing a domain fusion TLR2-4 receptor to enhance autophagy-dependent clearance of Staphylococcus aureus in macrophages.

This study examines how sugarcane rhizosphere fungal communities change over time, identifying key fungal genera and environmental drivers affecting their structure and disease risk.

This study identifies TRIM21 as a regulator of PKR-mediated protein translation by modulating PP1 ubiquitination and eIF2 dephosphorylation, revealing its role in antiviral defense and potential therapeutic applications.

This study identifies a compound that induces a persister state in melanoma cells, promoting differentiation and sensitizing them to a prodrug, offering a dual-target strategy for treatment.

This study shows that SMAD4 suppresses colitis-associated colon cancer by inhibiting CCL20/CCR6-mediated inflammation in mice.

The paper identifies CD133+ intercellsomes as a mechanism for intercellular communication to compensate for intracellular signal deficits in stress conditions.

This study investigates the evolutionary origins of the first three SARS-CoV-2 variants of concern, finding that they likely evolved within long-term infections in single individuals through multiple mutations.

This study investigates how female zebra finches generalize early learned song preferences to similar songs, finding that preference correlates with syllable overlap with the original tutor song.

This paper presents a chromosome-level genome of Ensete glaucum, revealing insights into chromosomal evolution and repetitive sequence dynamics in the Musaceae family.

This study identifies how flavivirus prM proteins interact with MDA5 and MAVS to inhibit RLR antiviral signaling, revealing species-dependent immune evasion mechanisms.

This study identifies elevated fungal translocation markers in PASC patients, which induce NF-κB inflammation through Dectin-1 signaling.

The paper identifies resR as a target of positive selection in Mtb clinical isolates, linking its mutations to antibiotic resilience and treatment failure.

This paper identifies a potent SARS-CoV-2 antibody, 553-49, that neutralizes the Omicron variant by targeting a conserved epitope and disassembling spike trimers.

The paper tests two chimpanzee adenovirus vectors expressing SARS-CoV-2 spike or nucleocapsid proteins in hamsters, finding that combining them enhances protection against COVID-19.

This study shows Tom70 regulates mitochondrial biogenesis and aging by coordinating transcription and protein import in yeast and Drosophila.

This study identifies aberrant mechanosensitive signaling in vascular endothelial cells as a driver of xanthine oxidoreductase activation and ROS generation, contributing to aortic aneurysm formation in Marfan syndrome.

This study designs bispecific antibodies from non-Omicron neutralizing antibodies that effectively neutralize the Omicron variant and related sarbecoviruses.

The paper assesses Trichoderma biodiversity in Ethiopian coffee rhizosphere soils and evaluates their biocontrol potential against coffee wilt disease.

This study uses molecular barcoding to analyze genetic diversity in Mtb strains, showing L2 strains have distinct growth dynamics and resist BCG vaccination.

This study shows that RfxCas13d causes mouse death by collateral cleavage of 28s rRNA, highlighting biosafety concerns for CRISPR-Cas13 systems.

The paper determines the asymmetric homodimer structure of mouse pendrin using cryo-EM, revealing its electroneutral anion exchange mechanism and pathogenetic mutation properties.

This study identifies hypoxia-regulated ubiquitination of DBC1 by SIAH2 and OTUD5 as a mechanism driving breast cancer progression.

This study uses single-particle tracking to analyze dynein motor behavior in live neurons, revealing that dynein switches between 1-5 motors and requires 2 ATP hydrolysis per step.

The paper identifies a TA system in Mtb, TacAT, where TacT acetylates tRNAs to inhibit translation and Pth reverses this effect, showing Pth's essentiality is unaffected by TacAT's absence.