S. Liu

This study identifies gene mutations in the PI3K/Akt pathway associated with immune thrombocytopenia (ITP) using whole-exome sequencing and functional analysis.

The paper uses single-cell multi-omics to analyze HCC cell lines, identifying metastasis potential heterogeneity and a hypoxic subgroup with poor prognosis.

The paper identifies ARID1A deficiency's role in promoting pancreatic tumorigenesis by reducing KRAS-induced senescence through upregulation of ALDH1A1 in mouse PanIN models.

This study reports the first systematic analysis of aphid and parasitoid wasp species composition and dynamics in maize fields of Jilin Province, China, over two years.

The paper identifies a peroxidase inhibitor, 6D1, that enhances kanamycin activity against carbapenem-resistant bacteria.

The paper shows mitochondria fragment and reassemble to form nuclei and intranuclear inclusions during nuclear development.

This study identifies key interferon stimulated genes (ISGs) that restrict SARS-CoV-2 infection by inhibiting viral entry, RNA synthesis, and release.

This study reevaluates Spinach-based RNA visualization in plants, showing potential for ex vivo and in vivo RNA monitoring.

This paper introduces a hierarchical 3D-motion learning framework to map animal spontaneous behavior by capturing kinematics and learning dynamic behavior patterns.

This study compares SARS-CoV-2 strains in hamsters, finding that the D614G spike variant shows higher replication and transmission efficiency.

This paper identifies a novel allele of the chromogen gene C from wild rice that regulates anthocyanin biosynthesis differently in indica and japonica subspecies.

This study reconstructs the lineage histories and differentiation trajectories of JAK2-mutant HSCs in MPN patients, finding the mutation occurs decades before diagnosis and drives exponential growth of mutated HSC populations.

This study analyzes the genetic diversity and population structure of Alpine plum to confirm its classification within the Armeniaca section and inform conservation strategies.

This study shows that activating CAR with HBx in mice leads to liver tumors with strong β-catenin activation, mirroring human HBV-related HCC.

This study investigates the force-dependent unwinding activity of SARS-CoV-2 nsp13 helicase using optical tweezers, revealing increased unwinding frequency, processivity, and velocity under destabilizing force.

This study identifies tembotrione-resistant sorghum genotypes, characterizes their resistance mechanism, and maps quantitative trait loci (QTLs) associated with metabolic resistance to this herbicide.

The paper examines how PD-L1 expression on tumor cells affects specific cell clusters in TCR-T cells through single-cell RNA sequencing and cytotoxicity assays.

The paper assesses how tumor PD-L1 levels impact TCR-T cell function and anti-PD-(L)1 efficacy using single-cell RNA sequencing and cellular assays.

This paper designs protein sequences by optimizing an energy landscape to ensure they fold into a desired structure, showing improved performance over traditional methods.

This study shows that the PRRA insert in SARS-CoV-2 and raTG13 Spike proteins affects ACE2 usage across species, altering cellular tropism.

This paper develops a lentiviral vector for β-thalassemia treatment that restores β-globin expression in Chinese patients with minimal tumorigenesis risk.

The paper identifies GRL0617 as a non-covalent inhibitor of SARS-CoV-2 PLpro with an IC50 of 2.1 μM, supported by co-crystal and NMR data showing its mechanism of action.

This study uses transcriptomics to resolve the phylogenetic relationships of Odonata, finding monophyletic damselfly and dragonfly families and estimating their origins in the late Triassic.

The paper shows red-light promotes mutualism between begomovirus and whitefly by stabilizing βC1, which inhibits plant defenses through interference with PIFs and MYC2 transcriptional activity.

DIRT/3D is a 3D root phenotyping platform for field-grown maize that measures 18 root architecture traits with high accuracy and heritability, aiding in breeding for climate resilience.

The paper identifies 13 breast epithelial cell clusters in healthy breast tissues and links some clusters to breast cancer origins and prognosis.

This study shows that HIV-1 Gag and Gag{Delta}p6 specifically dimerize on Psi RNA, supporting a p6-independent mechanism for viral particle assembly initiation.

The paper shows that effectors from an oomycete pathogen and an aphid pest both target the host E3 SUMO ligase SIZ1, with different mechanisms that enhance host susceptibility.

This paper shows how Begomovirus uses a phosphatase to suppress plant immunity, enhancing virus transmission by herbivore vectors.

This paper identifies and profiles bisecting N-acetylglucosamine modifications in human amniotic membrane through glycomic and glycoproteomic analyses, revealing 41 glycoproteins with this modification.