Y. Wang

This study links psychosocial experiences to mitochondrial biology in the human brain, finding positive experiences correlate with higher OxPhos machinery abundance and negative experiences with lower abundance.

The paper identifies elevated MMPs and NETs in CNS-TB patients and shows MMP inhibition improves survival in a mouse model.

This study investigates the role of liver-specific glucocorticoid receptor (GR) in alcoholic liver disease using knockout and knockin mice, finding that GR deficiency worsens steatosis and liver injury while GR overexpression provides protection.

The paper investigates the role of mixotrophic eukaryotes as bacterivores in a coastal region, finding they contribute significantly to bacterivory despite being less dominant than heterotrophs.

This study shows that non-core RAG regions reduce off-target V(D)J recombination and maintain genomic stability in BCR-ABL1+ B-ALL by improving RAG cleavage accuracy.

This paper presents the first telomere-to-telomere genome assembly of the soybean cultivar Zhonghuang 13, resolving gaps and identifying novel genes and structural variations.

This study exposes M.tb strains to human alveolar lining fluid and finds strain-specific and time-dependent gene expression changes, particularly in lipid metabolism and cholesterol degradation.

This study identifies SASH1 as a regulator of melanocyte stem cell maintenance, showing that the S519N variant disrupts its function and links to pigmentation disorders.

The paper presents a new microbial reference set with paired isolates from China, showing probiotic and cardiometabolic effects on hosts.

The paper identifies CRIHSP structures in human adaptive immunity genes, showing their association with genomic instability and recombination.

The paper determines the structure of AtABCG25, an ABA exporter, revealing its mechanism of ABA binding and transport through cryo-EM.

This paper introduces a voxelated bioprinting method to create double-network hydrogel droplets with precise 3D assembly and mechanical properties.

This study identifies a novel human antibody, AF-03, that targets MARV glycoprotein and shows neutralizing activity against MARV and related filoviruses.

This study investigates Erdr1's role in macrophage polarization and cell fate by showing it promotes IL-1β production in a dose- and density-dependent manner through interactions with YAP1 and Mid1.

The paper identifies RNA methylation and autophagy-related genes in COPD using bulk and single-cell RNA sequencing data and validates them in animal models.

This study shows NGAL deficiency causes Hemophilia-like bleeding and clotting issues by enhancing coagulation and suppressing antithrombin.

The paper determines cryo-EM structures of P2X7 receptor with antagonists and identifies key residues for subtype specificity, aiding in antagonist design.

The paper predicts three new mammalian echolocators using molecular convergence analyses and machine learning, with behavioral experiments confirming echolocation in shrew moles.

This study identifies glucocorticoid receptor activation in NK cells as a mechanism driving AREG-mediated immunosuppression in skin cancer, with therapeutic implications.

This study identifies two modules, Cep131-Cep162 and Cby-Fam92, that cooperatively maintain Cep290 at the basal body and initiate ciliogenesis.

This study curates a dataset of influenza HA antibodies and develops an explainable language model to predict antibody specificity, identifying and validating HA stem antibodies.

This study shows that IL-23 receptor signaling in ILC3s enables them to produce IFNγ and clear the live-attenuated oral Chlamydia vaccine intrOv from the gut, ensuring its safety.

The paper develops predictive models for protein-protein binding affinity using amino acid composition at interfaces and identifies key amino acids that influence binding strength.

This study identifies the CD36-PKM2-mtROS pathway as a mechanism by which oxidized LDL disrupts efferocytosis, contributing to atherosclerosis progression.

The paper identifies a new type of monocytic leukemia stem cell (m-LSC) in AML patients treated with venetoclax, showing its distinct characteristics and clinical relevance.

This study identifies ABA and BR as key regulators in overcoming inter-subgeneric hybridization barriers in water lily through transcriptomic and hormonal analyses.

This study shows that bacterial sphingolipids worsen colitis by reducing IL-22 production from ILC3 cells in mice.

This study analyzes stromal cells in renal cell carcinoma to identify molecular features and construct a prognostic model for clinical risk estimation.

This study demonstrates longitudinal awake mouse brain imaging using ultrasound localization microscopy, showing reduced vessel density and flow velocity after anesthesia recovery.

This study characterizes the antigenic properties and infectivity of the SARS-CoV-2 BA.2.86 variant, finding it evades immune responses but has reduced infectivity compared to previous variants.