Z. Xu

This study presents the structure of primate ferroportin and elucidates its mechanism of iron transport and regulation by hepcidin.

The paper investigates the mechanical anisotropy of ZIKV xrRNA1 using single-molecule nanopore sensing and molecular dynamics simulations, revealing its dependence on Mg2+ and tertiary interactions.

This study shows that human ILC2 cells can be activated by TLR4 signaling through LPS, leading to cytokine production and B cell activation, distinct from classical IL-33 activation.

This study shows that BCP and Pre-C mutations in HBV increase viral replication but reduce immune tolerance, with Pre-C mutations causing more severe immune responses and shorter viral persistence in mice.

This study shows that intermittent anti-PI3K treatment can overcome immune checkpoint therapy resistance in Pten-null prostate cancer by converting 'cold' tumors into T cell-inflamed ones.

This study shows auxin guides germ cell specification in Arabidopsis anthers by creating a centripetal gradient that is essential for GC initiation and patterning.

This study shows SpRY expands CRISPR editing in rice by recognizing diverse PAMs, enabling efficient genome modification across various loci.

This study shows that IgT is the main immunoglobulin induced in trout skin mucosa during bacterial infection, with SALT serving as a key inductive site.

This study shows neonicotinoids increase methane emission in Periplaneta americana by altering gut bacteria to produce more hydrogen, which methanogens use to generate methane.

The paper evaluates spatial adjustment methods for ordinal data in soybean iron deficiency chlorosis, finding SAR models perform best but none fully remove spatial patterns.

This study shows that overexpressing purple acid phosphatase 2 in chloroplasts and mitochondria improves ATP production, plant growth, and seed yield by balancing reducing equivalents and enhancing photosynthesis.

The paper develops deep learning models using RNA-seq data that incorporate isoform and exon information to improve smoking status prediction, achieving higher AUC than gene-level models.

This study identifies CD36-mediated lipid peroxidation driven by oxidized lipids as a mechanism suppressing anti-tumor CD8 T cell functions in murine tumors.

This study examines how maize plants respond to drought, flooding, and rewatering, finding that photosynthetic traits recover after rewatering, with resilience depending on drought severity and plant growth stage.

This study evaluates an intradermal DNA vaccine against SARS-CoV-2 in rhesus macaques, showing it induces immune responses and provides protection against viral challenge.

This study identifies CHK2 inhibition as a strategy to reduce hematological toxicity from PARP inhibitors by targeting the p53 pathway in blood cells.

This study analyzes immune responses in COVID-19 patients using single-cell RNA sequencing to identify differences in immune cell behavior across disease severity stages.

This study shows that excessive polyamine production in keratinocytes drives self-RNA sensing by dendritic cells, contributing to psoriasis inflammation.

B cells integrate innate TLR and adaptive CD40 signals to induce BATF3 transcription factor for production of IL-27, which together with INFg optimizes antibody responses.

This paper introduces an ultra-compact dual-band smart NEMS magnetoelectric antenna for wireless energy harvesting and magnetic field sensing in implantable medical devices.

The paper describes a rapid serological assay to detect functional antibodies blocking ACE2 recognition in vaccinated animals and infected patients.

The paper designs a framework combining generative AI and molecular docking to create target-specific chemical libraries, identifying potential drug repurposing candidates for SARS-CoV-2 Mpro.

This study generates a human peripheral myelination model from pluripotent stem cells and shows ZIKV induces GBS-like features in vitro.

This study develops a SARS-CoV-2 vaccine candidate using virus simulating particles that induces strong neutralizing immune responses with a single dose.

This study shows ACE2 and TMPRSS2 are expressed on human ocular surface cells, suggesting they can be infected by SARS-CoV-2.

PM2RA detects and quantifies microbial relationship alterations between healthy and diseased states, showing higher specificity and sensitivity than co-occurrence-based methods.

This study shows that iso-PhABA improves grape color and anthocyanin content more than ABA by enhancing enzyme activity and receptor affinity.

This study identifies BCAT2 as a suppressor of ferroptosis in cancer cells, showing its role in regulating glutamate levels and enhancing resistance to ferroptosis-inducing therapies.

The paper predicts nelfinavir as a potential inhibitor of 2019-nCov main protease using homology modeling, molecular docking, and binding free energy calculations.