D. Wang

This study shows that Tfh17 cells are more effective than Tfh1 and Tfh2 cells in maintaining memory responses after vaccination.

This paper demonstrates 6-target STED microscopy using exchangeable labels, improving multiplexing capabilities and reducing photobleaching in live-cell imaging.

This study identifies a point mutation in the CHLI gene of strawberry that affects leaf color and metabolism by reducing chlorophyll and flavonoid levels and altering light sensitivity.

This paper develops a long-circulating molecular brush to enhance aptamer stability and bioactivity in vivo.

The paper validates on-target and off-target effects of anti-Cryptosporidium drugs using a novel MDR1-transgenic host cell model and algorithms to quantify drug action contributions.

The paper constructs a promoter-GFP fusion reporter library to study the systemic expression patterns of 41 c-di-GMP metabolism-related genes in Pseudomonas aeruginosa under various growth conditions.

This paper investigates the cellular uptake, trafficking, and antisense gene regulation mechanisms of bottlebrush polymer-conjugated oligonucleotides in cancer cells.

The paper isolates rare memory B cells from vaccinated individuals to generate anti-poxvirus monoclonal antibodies, identifying one with high efficacy against viral infection.

AlphaFold2-RAVE generates thermodynamically ranked conformational ensembles using AlphaFold2 structures as initializations for AI-enhanced molecular dynamics simulations.

This study identifies a toxin-mediated policing system in Bacillus that punishes phenotypic cheaters, enhancing population fitness in plant rhizosphere and under stress.

This study shows the stem-loop II motif is critical for astrovirus replication but not for SARS-CoV-2.

This study identifies placental mammal-specific miRNAs and their targets in endometrial epithelial cells, showing their role in implantation and potential involvement in recurrent pregnancy loss.

This study links HIV-associated gut dysbiosis to cytokine production capacity in ART-suppressed PLHIV, identifying specific microbial strains associated with immune markers.

This study investigates the structural and biochemical features of Omicron BA.1 and BA.2 variants, showing increased infectivity and mouse ACE2 binding compared to wildtype, suggesting a potential human-cat-mouse-human transmission cycle.

This study compares IL13-ligand CAR designs to determine how co-stimulation domains affect tumor selectivity and anti-tumor activity against glioblastoma.

The study assesses the prevalence of Bourbon and Heartland viruses in ticks at an environmental field station, finding 3.9% and 7.6% positivity rates respectively.

This paper develops a method for live-cell RNA imaging using fluorescent nucleosides and shows accelerated RNA turnover and distinct RNA granules during oxidative stress.

This study investigates the role of GDF15 in APAP-induced liver injury in mice, finding no significant ameliorative effect from overexpression or supplementation of GDF15.

This paper develops temperature-sensitive nanothermometry probes to measure spatiotemporal thermodynamics of lysosomes and mitochondria in living cells, revealing distinct thermal responses to metabolic perturbations.

This study shows Arbidol inhibits esophageal squamous cell carcinoma growth by targeting the ATR kinase and disrupting the DNA replication pathway.

This study constructs multiscale models of SARS-CoV-2 using coarse-grained molecular dynamics simulations and experimental data, revealing dynamic behavior of membrane proteins and lipid interactions.

This study constructs a pan-vaccine (S6) based on the evolutionary patterns of SARS-CoV-2 spike protein to combat diverse variants, showing broader neutralization than existing vaccines.

This study examines how insulin affects endometrial transcript expression in a microfluidic model, identifying altered translation-related transcripts that may reduce endometrial implantation capacity.

This study identifies GRP78 as a positive regulator of HBV enveloped-particle secretion through direct interaction with preS1, suggesting it as a potential therapeutic target.

This study compares N-glycosylation profiles of SARS-CoV-2 spike proteins with D614G mutation and ancestral form using mass spectrometry, finding changes in glycan distribution and complexity.

This study identifies DDX18 as a negative regulator of IRF3 binding to the IFN-β promoter, suppressing type I IFN production during viral infection.

The paper examines sex differences in avian parental care across species, finding that care roles vary and are influenced by factors like sexual selection and paternity certainty.

This study identifies OsMADS58's role in stabilizing gene regulatory circuits during rice stamen development using CRISPR knockout and transcriptomic analysis.

This study identifies a novel cannibalism mechanism in Bacillus velezensis SQR9 mediated by bacillunoic acids, enhancing biofilm formation and interspecies competition through a two-component regulatory system.