Y. Li

The paper develops a digital diagnostics platform using NFC-enabled potentiostat and nitrocellulose-based electrodes for electrochemical detection of pathogens at the point-of-need.

The paper identifies RipBH, a virulent type III effector from Ralstonia solanacearum, which induces autophagy-associated cell death and is essential for potato brown rot pathogenesis.

This study maps the dynamic multicellular ecosystem of radiation-induced intestinal injury using single-cell RNA sequencing, revealing heterogeneous radiosensitivities and cellular interactions.

This paper introduces a new spectroscopic imaging method that improves signal intensity by over 500-fold for chemical imaging.

This study characterizes the pharmacological response of the GRABeCB2.0 sensor to endocannabinoids and cannabinoids, finding that its EC50 values for 2-AG and SR1 match CB1R potencies, while others show lower EC50s, and CBD acts as a negative allosteric modulator.

This study shows that the type VI secretion system in Geobacter metallireducens affects DIET by altering gene expression and electron transfer efficiency.

This study identifies Fkbp5 as a regulator of epithelial cell quiescence-proliferation transition via Akt signaling in zebrafish using transcriptomics and genetic approaches.

The paper evolves haploid and diploid yeast populations in different environments and finds common, unpredictable pleiotropic effects of adaptive mutations in non-home environments.

The paper identifies cGLRs as a widespread family of pattern recognition receptors in animal innate immunity and elucidates their conserved signaling mechanisms.

This study identifies the ATM-E6AP-MASTL axis as a timer-like mechanism that ensures the transient DNA damage checkpoint by promoting cell cycle recovery.

The paper develops a high-throughput platform for screening functional neo-antigens and their specific TCRs using droplet microfluidics and DNA barcoding.

This study characterizes 52 patient-derived glioma cell lines with whole-genome sequencing, RNA-seq, and drug response screening, identifying three subtypes and their drug sensitivities and tumorigenic potential.

This paper develops robotic fibers (fiberbots) that enable high-precision motion through thermal expansion, demonstrating scalability and integration with medical devices for potential applications in surgery and biomedical engineering.

This study reprograms human fibroblasts into anti-aging neural stem cells using miR-302a, which enhance cognitive function and extend lifespan in mice with Alzheimer's.

This paper develops a deep learning method to assess chondrocyte viability using label-free two-photon microscopy images from rat and porcine cartilage, achieving 95% accuracy.

The paper identifies a non-canonical IRAK signaling pathway triggered by DNA damage that promotes anti-apoptosis and is activated by ionizing radiation and genotoxic therapies.

The paper quantifies UPF3A and UPF3B expression in mouse tissues, finding UPF3A is ubiquitously expressed, contradicting previous assumptions of limited expression.

This study identifies FLZ13 as an ABI5-interacting protein that co-represses growth-related genes to delay seed germination in response to ABA.

The paper was withdrawn due to the need for additional experimental evidence and reorganization of data and writing.

This study shows that PIF3, a transcription factor, regulates root penetration in Arabidopsis by interacting with FER, a receptor kinase, and modulating mechanosensitive ion channels and root cap cell sloughing.

This study identifies a unique GSH utilization pathway in Francisella, revealing a pseudogenized transporter gene in pathogenic strains and its role in environmental niches.

This study shows that steamed broccoli sprouts reduce DSS-induced colitis in mice by preserving gut microbial diversity and biogeography.

This study shows that a broccoli sprout diet reduces symptoms of Crohn's-like disease in IL-10-KO mice, with stronger effects in younger mice.

This paper introduces multifunctional ferromagnetic fiber robots capable of navigation, sensing, and treatment in minimally invasive surgery, demonstrating their use in electrophysiology sensing and localized treatment.

The paper presents cryo-EM structures of human NaV1.6 channels with and without 4,9-anhydro-tetrodotoxin, revealing Na+ selectivity and inhibition mechanisms.

This study shows that Vcam1 expression in cholangiocarcinoma cells is regulated by peritumoral myofibroblasts, promoting tumor dissemination while suppressing growth.

This study shows USP39 promotes liver cancer by regulating alternative splicing through interaction with SRSF6/HNRNPC, identifying it as a potential therapeutic target.