Author
C. Yang
The First Hospital of Kunming
Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.
Biology Disciplines
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2017-2026 · peak 30/yrCo-Author Collaboration Network
10 top collaborators · 33 mutual co-author links133 papers
Recent·Most cited
- BiophysicsbioRxiv
Field dependent deep learning enables high-throughput whole-cell 3D super-resolution imaging
This paper introduces FD-DeepLoc, a deep learning method for high-throughput 3D super-resolution imaging over a large field of view using a sCMOS camera.
DOI 10.1038/s41592-023-01775-5 - Plant BiologybioRxiv
ATM-Mediated Double-Strand Break Repair Is Required for Meiotic Genome Stability at High Temperature
J. Zhao, X. Gui, Z. Ren…·B. Liu
This study shows ATM is essential for maintaining meiotic genome stability in Arabidopsis at high temperatures, acting through the MRN complex and chromosome axis, independent of RAD51.
DOI 10.1111/tpj.16145 - BiochemistrybioRxivPreprint
Highly Sensitive and Specific Amyloid-β Oligomers Detection Using CRISPR-Cas12a Probe System aided by Graphene Oxide for Early Diagnosis of Alzheimer's Diseases
This study develops a CRISPR-Cas12a-based sensor enhanced with graphene oxide for specific and sensitive detection of amyloid-β oligomers, aiming to enable early Alzheimer's disease diagnosis.
DOI 10.1101/2022.09.27.509482 - Plant BiologybioRxivPreprint
Genome-scale mRNA transcriptomic insights into the mature growth dynamic of Cigar tobacco leaves
J. Yang, D. Wan, B. Qiao…·C. Yang
This study uses transcriptomic analysis to examine gene expression changes in cigar leaves at different growth stages, identifying key pathways and regulatory networks associated with maturity.
DOI 10.1101/2022.09.26.509548 - Animal Behavior & CognitionbioRxiv
Physiological state matching in a pair bonded poison frog
J. P. Nowicki, C. Rodriguez, J. C. Lee…·L. A. O'Connell
The paper investigates emotional contagion in poison frogs, finding physiological state-matching between male and female partners, independent of behavioral or reproductive factors.
DOI 10.1098/rsos.240744 - BioengineeringbioRxiv
Targeting caveolae to pump bispecific antibody to TGF-β into diseased lungs enables ultra-low dose therapeutic efficacy
A. H. Kadam, K. Kandasamy, T. Buss…·J. E. Schnitzer
This paper develops a bispecific antibody that targets caveolae to deliver TGF-β inhibitors specifically to lungs, achieving ultra-low dose therapeutic efficacy in a rat model.
DOI 10.1371/journal.pone.0276462 - Cancer BiologybioRxiv
Induction of PARP7 Creates a Vulnerability for Growth Inhibition by RBN2397 in Prostate Cancer Cells
C. YANG, K. Wierbilowicz, N. M. Dworak…·B. M. Paschal
This paper shows that inhibiting PARP7 with RBN2397 reduces prostate cancer cell growth through multiple mechanisms, including trapping PARP7 in the nucleus and affecting gene expression.
DOI 10.1158/2767-9764.crc-23-0086 - Animal Behavior & CognitionbioRxivPreprint
Rates but not acoustic features of ultrasonic vocalizations are related to non-vocal behaviors in mouse pups
N. M. Pranic, C. Kornbrek, C. Yang…·K. Tschida
This study finds that non-vocal behaviors, particularly active movements, correlate with the rate but not the acoustic features of isolation ultrasonic vocalizations in mouse pups.
DOI 10.1101/2022.08.05.503007 - MicrobiologyCell ResearchPeer-reviewed
Omicron-specific mRNA vaccine elicits potent immune responses in mice, hamsters, and nonhuman primates
Y. Wu, Y. Shen, N. Wu…·Y. Wang
This study develops an Omicron-specific mRNA vaccine that shows superior neutralizing antibody responses in mice, hamsters, and macaques compared to existing vaccines.
- MicrobiologybioRxivPreprint
Helicobacter chronic stage inflammation undergoes fluctuations that are altered in tlpA mutants
K. S. Johnson, C. Yang, J. E. Carter…·K. M. Ottemann
This study shows that H. pylori chronic inflammation fluctuates over time, and tlpA mutants alter these dynamics without affecting colonization levels in later stages.
DOI 10.1101/2022.08.01.502425 - BiochemistrybioRxiv
Comprehensive isotopomer analysis of glutamate and aspartate in small tissue samples
F. Cai, D. J. Bezwada, L. Cai…·R. J. DeBerardinis
This paper develops an MS method to analyze all 16 aspartate and 32 glutamate isotopomers with high sensitivity, enabling pathway discrimination and metabolic heterogeneity studies in human tumors.
DOI 10.1016/j.cmet.2023.07.013 - BioengineeringbioRxiv
Wireless Neuromodulation at Submillimeter Precision via a Microwave Split-Ring Resonator
J.-X. Cheng, C. Yang, C. Marar…·N. Zheng
This paper introduces a microwave split-ring resonator that enables submillimeter precision neuromodulation by enhancing microwave field localization and efficiency for inhibiting neurons.
DOI 10.1126/sciadv.ado5560 - BioengineeringbioRxiv
Label-Free Hyperspectral Imaging and Deep-Learning Prediction of Retinal Amyloid β-Protein and Phosphorylated Tau
X. Du, Y. Koronyo, C. Yang…·L. Gao
This paper develops a label-free hyperspectral imaging method combined with deep learning to detect and predict retinal amyloid β-protein and phosphorylated tau in Alzheimer's disease.
- Cell BiologybioRxivPreprint
DINAVID: A Distributed and Networked Image Analysis System for Volumetric Image Data
S. Han, A. Chen, S. Lee…·E. J. Delp
DINAVID provides a cloud-based system for remote 3D microscopy image analysis and visualization, designed to handle large datasets and improve accessibility.
DOI 10.1101/2022.05.11.491511 - Cell BiologybioRxivPreprint
Sequential functional differentiation of luminal epithelial cells regulated by maternal and embryonic signaling in the mouse endometrium
H. Wang, D. Li, J. Liu…·H. Sun
The paper identifies maternal and embryonic signaling-driven differentiation of luminal epithelial cells in the mouse endometrium and shows conservation in humans.
- ImmunologybioRxivPreprint
A cocktail containing two synergetic antibodies broadly neutralizes SARS-CoV-2 and its variants including Omicron BA.1 and BA.2
X. Zhang, F. Luo, H. Zhang…·A. Huang
This paper identifies a potent antibody cocktail that synergistically neutralizes SARS-CoV-2 and its variants, including Omicron BA.1 and BA.2.
DOI 10.1101/2022.04.26.489529 - Cell BiologybioRxiv
Cystin is required for maintaining fibrocystin (FPC) levels and safeguarding proteome integrity in mouse renal epithelial cells A mechanistic connection between the kidney defects in cpk mice and human ARPKDRunning title: Cystin deficiency results in FPC degradation
Y. Zhang, C. Yang, W. Wang…·Z. Bebok
This study shows cystin deficiency reduces fibrocystin (FPC) levels in mouse renal cells, leading to proteome changes and cyst formation similar to ARPKD.
DOI 10.1096/fj.202300100r - ImmunologybioRxivPreprint
Costimulation of TLR8 responses by CXCL4 in Human Monocytes Mediated by TBK1-IRF5 Signaling and Epigenomic Remodeling
C. YANG, M. Bachu, Y. Du…·L. B. Ivashkiv
This study shows CXCL4 enhances TLR8 responses in human monocytes by promoting inflammatory gene transcription and IL-1β production through TBK1-IRF5 signaling and chromatin remodeling.
DOI 10.1101/2022.03.28.486089 - Cell BiologybioRxiv
Bipartite recruitment of PCH2 and COMET to the synaptonemal complex drives chromosome axis reconstruction leading to crossover restriction
C. Yang, K. Sofroni, Y. Hamamura…·A. Schnittger
This study shows that PCH2 and COMET are recruited to the synaptonemal complex via ZYP1 to regulate ASY1 removal and crossover restriction during meiosis.
DOI 10.1093/nar/gkac1160 - Cell BiologybioRxiv
The Arabidopsis Hop1 homolog ASY1 mediates cross-over assurance and interference
G. Pochon, I. M. Henry, C. Yang…·A. Schnittger
This study investigates the role of ASY1 in meiotic crossover (CO) assurance and interference in Arabidopsis, showing that reduced ASY1 activity leads to altered CO distribution and genomic instability.
DOI 10.1093/pnasnexus/pgac302 - EcologybioRxiv
Engineering ecologically complementary rhizosphere probiotics using consortia of specialized bacterial mutants
C. Yang, J. Li, A. Jousset…·V.-P. Friman
This study improves plant growth-promotion by engineering specialized bacterial mutants within a single species and assembling them into consortia that enhance root colonization and disease resistance.
DOI 10.7554/elife.90726 - Cancer BiologybioRxiv
Slow-cycling cells in glioblastoma: a specific population in the cellular mosaic of cancer stem cells
C. Yang, G. Tian, M. Dajac…·L. P. Deleyrolle
This study compares slow-cycling cells with cancer stem cell (CSC)-like cells in glioblastoma, showing phenotypic and functional heterogeneity and supporting the cancer stem cell mosaicism model.
DOI 10.3390/cancers14051126 - MicrobiologybioRxivPreprint
The tyrosine phosphatase PRL regulates attachment of Toxoplasma gondii to host cells and is essential for virulence
C. Yang, W. J. Blakely, G. Arrizabalaga
This paper identifies TgPRL as a critical tyrosine phosphatase in Toxoplasma gondii that regulates attachment to host cells and virulence, with implications for therapeutic intervention.
DOI 10.1101/2022.01.24.477641 - MicrobiologybioRxiv
Conserved Untranslated Regions of Multipartite Viruses: Natural Markers of Novel Viral Genomic Components and Tags of Viral Evolution
S. Zhang, C. Yang, J. Wu…·M. Cao
This study identifies novel viral genomic components and evolutionary patterns using conserved untranslated regions (UTRs) and UTR-backed iterative BLASTn in multipartite viruses.
DOI 10.1093/ve/veae004 - BiochemistrybioRxivPreprint
The anti-angiogenic compound dimethyl fumarate inhibits the serine synthesis pathway and increases glycolysis in endothelial cells
M. C. Ocana, C. Yang, M. Bernal…·M. A. Medina
This study shows dimethyl fumarate inhibits serine synthesis and increases glycolysis in endothelial cells, potentially explaining its anti-angiogenic effects.
DOI 10.1101/2021.12.13.472337 - Cell BiologybioRxiv
Metformin abrogates pathological TNF-α-producing B cells through mTOR-dependent metabolic reprogramming in polycystic ovary syndrome
N. Xiao, J. Wang, T. Wang…·L. Cheng
This study shows metformin reduces TNF-α production in B cells of PCOS patients and mice by inhibiting mTOR and altering metabolism.
- BioengineeringbioRxivPreprint
Optogenetic operated probiotics to regulate host metabolism by mimicking enteroendocrine
X. Zhang, N. Ma, W. Ling…·H. Wang
The paper develops an optogenetic probiotics system to control enteroendocrine hormone secretion in vivo, demonstrating improved glucose control in animal models.