L. Zhao

The paper models how traits in microbial communities evolve under eco-evolutionary dynamics by integrating population genetics with resource-mediated dynamics.

This study investigates the role of the BMPR-II-SMAD3/MRTF complex in ASMC proliferation and migration in asthma, finding it contributes to airway remodelling.

This study examines sex-specific effects of uteroplacental insufficiency-induced low birth weight on hepatic cholesterol metabolism in adult guinea pigs, finding increased cholesterol and altered gene expression in males but not females.

A mouse-adapted SARS-CoV-2 strain with RBD mutations caused 100% mortality in aged male BALB/c mice and showed altered receptor binding affinity.

This study investigates the evolutionary basis of Drosophila suzukii's egg-laying behavior by combining behavioral, genomic, and gene expression analyses with closely related species.

The paper investigates cross-reactivity between mugwort and house dust mite allergens, finding that mugwort tropomyosin induces a non-Th2 response in allergic rhinitis patients.

This study develops and characterizes high-affinity mouse monoclonal antibodies against SARS-CoV-2, showing their neutralizing and diagnostic potential.

This study uses single-cell RNAseq to analyze adult Schistosoma mansoni parasites, identifying a key regulator of blood feeding and gut maintenance.

This study shows that SARS-CoV-2 attached to salmon can remain infectious for over a week at 4°C, indicating a potential transmission risk in seafood markets.

This study identifies immunodominant and neutralizing epitopes on SARS-CoV-2 proteins through computational simulation and experimental validation in mice.

The paper estimates the effective population size of influenza virus within-host infections, finding it large enough that genetic drift has minimal impact, with positive selection limited by infection duration.

The paper examines ACE2 expression on immune cells and finds that activated type 1 macrophages (M1) have high ACE2 expression, suggesting they may be targeted by SARS-CoV-2.

This paper identifies and characterizes the NIC1-locus in tobacco, showing it regulates nicotine biosynthesis through ERF genes that function downstream of NtMYC2 in the JA signaling pathway.

The paper identifies AMPK substrates and their roles in DNA damage response and histone acetylation through phosphoproteomics and histone modification analysis.

This study shows that altered N-glycan composition in Chlamydomonas reinhardtii reduces flagella-mediated adhesion and surface binding.

This study identifies 5mC regulators as prognostic markers in glioma using multi-omics analysis and develops a risk model to predict patient outcomes.

This study infects hACE2 transgenic mice with SARS-CoV-2 and observes pathogenic effects, confirming Koch's postulates and establishing a model for vaccine and therapeutic development.

A 573 bp insertion in the YFT1 gene's 5' UTR disrupts ethylene signaling and carotenoid synthesis, causing yellow fruit in tomato mutants.

This study identifies a vertically transmitted core virome in Aedes albopictus mosquitoes across developmental stages and continents, and finds a novel virus related to Yongsan bunyavirus 1.

The paper uses a HOXA9-mCherry reporter and CRISPR/Cas9 screens to identify USF1/USF2 as regulators of HOXA9 in MLLr leukemia, showing their role in leukemia cell proliferation.

The paper analyzes the Human Protein Atlas database to identify potential key molecules in the airway epithelial cell microenvironment that may facilitate SARS-CoV-2 entry and immune response activation.

This study investigates the evolution of sex-biased gene expression in Drosophila brain tissues, finding enrichment on the X chromosome and evidence of directional selection and genetic constraints.

This study compares non-Cochrane nursing systematic reviews with their PROSPERO-registered protocols, finding widespread discrepancies with few explanations.

The paper investigates how β-alanine and L-carnosine affect pork quality by modulating glycolysis and AMPK activity in porcine muscle.

This study identifies KMT2D as a tumor suppressor in pancreatic cancer, linking TGF-β signaling to the non-canonical activin A pathway through miR-147b and showing its role in cancer cell plasticity and metastasis.

This study shows that rhesus macaques infected with SARS-CoV-2 are protected from reinfection during early recovery, likely due to enhanced neutralizing antibodies.

This study develops an AI system to identify fetal nucleated red blood cells using deep learning, achieving high accuracy and sensitivity in testing.

This study profiles the 2-hydroxyisobutyrylome in common wheat, identifying Khib modification sites and their roles in metabolic pathways and enzyme regulation.

This study demonstrates that cross-feeding between Thauera aminoaromatica and Rhodococcus pyridinivorans drives quinoline degradation in a denitrifying bioreactor through 2-hydroxyquinoline as an intermediate.

This study shows that reducing ACSL1 in cardiomyocytes prevents lipotoxicity and improves heart function in obese mice.