X. Wang

This paper introduces MLC-Seq, a method to sequence full-length tRNA isoforms and quantify RNA modifications, demonstrating its application on yeast and mouse tRNAs.

The paper evaluates lectins for anti-rabies virus activity, identifies Urtica dioica Agglutinin (UDA) as effective in preventing RABV infection in a muscle explant model.

This study identifies how ZIKV sfRNA interacts with NS5 to inhibit STAT1 phosphorylation, promoting viral pathogenesis in placental and neural tissues.

This study investigates how PSMA-targeted nanobubbles enhance ultrasound imaging in prostate tumors by being internalized and retained in intracellular vesicles, leading to prolonged signal and stability.

This study shows EBV miRNAs significantly remodel the tumor transcriptome by suppressing immune responses in EBV-associated cancers.

This paper introduces a metabarcoding pipeline to reduce errors in bulk-sample sequencing, showing reduced false positives and biases but no recovery of relative-abundance information.

The paper investigates how AKR1C and NADH contribute to cis-platin resistance in HepG2 cells using transcriptomic and metabolic analysis.

This paper develops and characterizes SARS-CoV-2 RBD-specific alpaca nanobodies, showing improved binding affinity and neutralizing potency through bivalent engineering.

The paper identifies three plasmid combinations that enhance the spread of ST11/CG258 carbapenemase-producing Klebsiella pneumoniae in China through genomic and epidemiological analysis.

This study shows that INT-767 prevents fibrosis in iPSC-derived renal organoids by modulating the TEAD4/TAZ pathway.

This paper introduces a reduced graphene oxide membrane as a supporting film for cryo-EM, improving resolution and particle absorption for sub-100 kDa biomolecules.

The paper identifies a novel subtype of therapy-induced prostate cancer cells with hybrid E/M and stem-like traits, showing their dependency on HER2/3 signaling and resistance to AR inhibition.

This study investigates how PAPD5 and PAPD7 stabilize HBV RNA and shows that PAPD5 is dominant in protecting the poly(A) tail, while PAPD7 acts as a backup mechanism.

This study identifies and characterizes brevibacillin 2V, a novel antimicrobial lipopeptide with low hemolytic activity against eukaryotic cells, showing promise for antibiotic development.

The paper shows that loss of Usp22 increases H2Bub1 levels, leading to enhanced ISG expression and IFN immunity in mice.

This study identifies ZmLBD5 and ZmLBD33 as class II LBD genes in maize that regulate gibberellin and abscisic acid biosynthesis, affecting plant growth and drought tolerance.

This study identifies ANP32A as a repressor of Wnt signaling that protects against joint and heart disease by inhibiting Wnt target genes and oxidative stress.

This study identifies and validates SARS-CoV-2 CD8+ T cell epitopes, demonstrates their cross-presentation, and shows the efficacy of peptide vaccines in transgenic mice.

This study identifies that SARS-CoV-2 nucleocapsid protein undergoes phase separation, which can be modulated by small molecules, offering new therapeutic strategies against COVID-19.

This paper develops a method to create 3D vascularized tissues using bioprinting and surgical anastomosis, showing improved viability and functionality in liver-like constructs.

This study identifies NMD as a vulnerability in cancer cells with SF3B1 and U2AF1 mutations, showing increased sensitivity to NMD inhibition and potential therapeutic targeting.

This study shows that EGCG from green tea inhibits SARS-CoV-2 and its variants by blocking spike protein binding to ACE2 receptors.

The paper sequenced two mangrove species to show extensive gene flow after speciation, with many small introgression blocks and genomic islets contributing to speciation.

The paper investigates the metapopulation structure of marine bacteria associated with diatoms, finding that closely related bacterial populations are host-specific and show functional differentiation.

This study evaluates antibody resistance and ACE2 usage in SARS-CoV-2 variants, finding SA501Y.V2 shows the highest resistance and expanded host range.

This study shows that potassium and nitrate together reduce ammonium toxicity in rice roots by improving growth and correcting auxin distribution and cell morphology.

The paper compares SARS-CoV-2 replication in pediatric and adult nasal epithelial cells, finding lower viral titers in children for ancestral and Delta variants, but higher replication for Omicron.

This study identifies stromal inflammation as a key driver of hematopoietic aging and shows that blocking IL-1 signaling can improve hematopoietic regeneration.

This study identifies BIRG1 as a chloride efflux transporter in rice that regulates grain size and salt tolerance by controlling chloride homeostasis.

This study identifies differentially regulated pathways and candidate driver genes in hepatocellular carcinomas through proteogenomic analysis across clinical stages and etiologies.