X. Wang

This study identifies a conserved SLiM in p107 that mediates B55 recruitment and dephosphorylation, revealing a general mechanism for PP2A/B55 substrate recognition.

The paper shows that FGFR inhibitors cause SWI/SNF complex dismissal from YAP-dependent enhancers, leading to adaptive resistance in TNBC through epigenetic and metabolic changes.

This study identifies PAQR3 as a predictor of epirubicin response in TNBC and shows that MAPK inhibition can reverse resistance caused by miR-138-5p-mediated PAQR3 downregulation.

The paper uses single-cell RNA analysis to compare immune cell profiles in young and old mice, finding higher proportions of effector cells in old mice that may enhance tumor defense.

The paper assembles a chromosome-scale, allele-aware autotetraploid genome of alfalfa cultivar Zhongmu-4 and identifies 101 SNPs associated with 27 agronomic traits using GWAS.

This study examines root trait interactions and deep nitrate capture in switchgrass ecotypes under water and nitrogen stress, finding shared and distinct responses and a link between deep rooting and aboveground growth.

This study shows that RIPK3 phosphorylation at S165/T166 switches its function from necroptosis to apoptosis, driving corpus luteum regression via PGF2-induced apoptosis.

The paper identifies a selective sweep in the Spike gene of SARS-CoV-2 that enhanced human adaptation by improving binding to human ACE2 and replication in human cells.

This study analyzes the effects of seed coat color and seed weight on protein, oil, and fatty acid contents in soybean germplasms, finding significant variations in fatty acids and a trade-off between oleic and linoleic acids.

This study identifies novel regulatory modules involving ZmBEH1 and ZmBZR1 that control leaf angle in maize, offering new gene editing targets for improving plant architecture.

This study identifies and characterizes six AcMNPV-encoded miRNAs, showing they regulate both viral and host genes through suppression or enhancement of target expression.

This study compares three qRT-PCR assays for SARS-CoV-2 detection, finding that CCDC and IPBCAMS N gene assays outperformed WHO assays, while IPBCAMS ORF 1b assay had higher detection rates than others.

The paper resurrects a functional internal ribosome entry site (IRES) from a 700-year-old ancient virus, showing it supports translation and virus infection in a modern context.

This study links high current production in Shewanella oneidensis to biofilm formation on electrospun carbon nanofiber anodes, showing fiber diameter affects surface area and pore size.

This study shows that image quality metadata improves fish species classification by CNNs, with high-quality images achieving higher F1 accuracy than low-quality ones.

This study identifies a novel folliculogenesis and follicular placentation mechanism in black rockfish, highlighting hormonal changes and conserved genes in placental development.

This study investigates the role of the abaI/abaR quorum sensing system in Acinetobacter baumannii virulence, showing its impact on growth, biofilm formation, antimicrobial susceptibility, and gene expression.

The paper reconstructs the protophloem developmental trajectory in Arabidopsis root cells to show how maturation gradients and transcription factors regulate cell specialization.

The study identifies a 416-bp deletion in the AFF gene's promoter that reduces its expression, leading to all-flesh tomato fruits and providing insights into berry fruit evolution.

The paper develops a cross-nearest neighbor/Monte Carlo algorithm to analyze interactions between p53, Mdm2, and MEG3 using single-molecule localization microscopy in U2OS cells.

This study identifies the structural and molecular mechanisms of two neutralizing antibodies against FMDV, showing they disrupt virus-receptor interactions and provide prophylactic and therapeutic benefits.

This study examines how different coral compartments shape microbial evolution by analyzing genome sequences of Rhodobacteraceae in mucus and skeleton, identifying genetic adaptations to compartment-specific environments.

This study analyzes H7N9 virus genome mutations in human clinical samples to identify potential adaptations during infection.

This study characterizes the dynamic changes in B-cell receptor repertoires of COVID-19 patients using next-generation sequencing, revealing clonotype overlap, lineage expansion, and V gene usage patterns.

This paper investigates the catalytic mechanism of SznF, revealing an unusual N-nitrosation pathway involving electron shuttling without high-valent iron species.

This study identifies GajA as a nucleotide-regulated endonuclease from the Gabija bacterial defense system, which is inhibited by NTP and dNTP but activated during phage infection.

This study identifies SARS-CoV-2 spike protein as a direct activator of TLR4 signaling in immune cells, leading to sepsis-related inflammation.

This paper investigates how TxtC catalyzes sequential hydroxylation of thaxtomin D, revealing that aliphatic hydroxylation is preferred due to lower energy barriers and conformational changes induced by intermediate hydroxyl groups.

This study shows that combining Arid1a loss and KrasG12D expression in mice leads to invasive vaginal squamous cell carcinoma, highlighting the need for both genetic hits to drive gynecologic malignancy.