D. Wang

This study shows that trehalose supplementation remodels the human gut microbiota, preventing simulated Clostridioides difficile infection in an in vitro model.

This study uses machine learning to uncover hidden song dialects in zebra finches that influence mate choice, showing cultural transmission drives assortative mating.

This study identifies two novel colon-specific mononuclear phagocyte subsets that are critical for Th17 immunity in the colon.

The paper introduces membrane contact probability (MCP) as a predictive metric for membrane proteins, showing it improves contact map and structure predictions.

This study combines enhanced biological phosphorus removal with nitrite accumulation in a reactor treating synthetic digested manure wastewater, achieving high phosphorus removal and stable nitrite levels.

The paper develops a novel isothermal amplification method (LMCP) for detecting Oryza sativa ITS with higher sensitivity and speed compared to LAMP.

The paper develops a non-infectious SARS-CoV-2 replicon system to study viral replication and test antiviral compounds, revealing cell-line-specific inhibitor potencies.

This study develops upconversion nanoparticles to monitor mitochondrial temperature dynamics in living cells and shows distinct thermal responses to various stimuli.

The paper identifies cis-regulatory changes in a gene linked to adaptive radiation in cichlid fishes by showing their impact on gene expression patterns across lineages.

This study develops and validates an improved EBPR model (iEBPR) to simulate PAO-GAO competition under extended anaerobic conditions using single-cell Raman micro-spectroscopy data.

This study identifies a regulatory pathway involving CPEB2 m6A methylation that affects BTB permeability through SRSF5 and P51-ETS1, enhancing drug efficacy in glioma treatment.

This study shows allantoin induces pruritus in CKD by activating MrgprD and TRPV1 in DRG neurons.

This study identifies nickel-ligated proteins as the conductive core of cable bacteria's periplasmic wires, revealing a novel mechanism for long-range electron transport.

This paper introduces a fast 3D printing method called FLOAT to create large-scale biocompatible hydrogel models with minimal deformation and cellular injury.

This study uses TRACE-seq to analyze single throat swabs, integrating SARS-CoV-2 genome, microbiome, antibiotic resistance, and host response data.

This study shows auxin guides germ cell specification in Arabidopsis anthers by creating a centripetal gradient that is essential for GC initiation and patterning.

This study shows that inhibiting SHP2 in endothelial cells reduces tumor growth by damaging the tumor vasculature, independent of SHP2 effects in tumor cells.

This study shows that Eng1 and Ywp1 in C. albicans reduce Dectin-1 binding by masking β-glucans, thereby decreasing immune recognition and virulence.

This study identifies Dhx36 as essential for skeletal muscle stem cell regeneration by regulating mRNA translation through binding and unwinding 5' UTR G-quadruplex structures.

This paper develops a deep learning system for gastric cancer detection using histopathological images, achieving high sensitivity and robust performance across different scanners.

This study shows miR-224 promotes HCC cell migration and invasion by targeting HOXA5 and ADAM17, suggesting it as a potential therapeutic target.

This study identifies an epigenetic vulnerability in PI3K/AKT inhibitor-resistant cancers, showing that targeting bromodomain or HDAC inhibitors can overcome resistance by modulating histone acetylation at growth factor/receptor gene loci.

The paper identifies genetic elements and QTL associated with stem prickle development in roses, linking prickle density to water-related adaptations.

This paper develops a nanoparticle-mediated method to enable in vivo analysis of RAS protein activity by delivering a fluorescent GTP analog into cells.

The paper investigates the evolution of a sex megachromosome in cichlid fish, finding it consists of three distinct regions and contains unique genomic features.

This study identifies the PacC-dependent pH signaling pathway in the rice blast fungus Magnaporthe oryzae, showing it regulates host pH changes and the switch between biotrophic and necrotrophic growth, essential for disease development.

This paper describes a rapid method using LAMP and Nanopore Flongle for detecting SARS-CoV-2 and other respiratory viruses in under two hours.

This study identifies pectate lyase (PL) as a susceptibility factor in tomato fruit ripening, showing that suppressing PL reduces fungal disease susceptibility without affecting defense responses.