F. Yang

The paper examines age-related differences in B cell memory to coronaviruses and other pathogens across tissues and age groups, finding higher frequencies of class-switched memory B cells in children.

This paper describes a protocol for inducing collagen-induced arthritis (CIA) in mice using bovine collagen type II and Freund's adjuvants, and reports associated enteritis and arthritis outcomes.

The paper presents an improved strategy for deep N-glycomics with optimized sample prep, isotope-based QC, new libraries, and algorithms, but the manuscript was withdrawn due to incomplete data.

Increased light availability enhances stress resistance in Halimeda opuntia by the accumulation of soluble organic molecules and enzyme-driven activities to alleviate ocean acidification stress.

This study shows that MAPK6 activates AKT to promote cancer, leading to oncogenic outcomes and poor patient survival in multiple cancers.

This study identifies differentially expressed proteins and phosphosites in porcine granulosa cells during follicular atresia, revealing potential biomarkers and pathways involved in the process.

This paper validates a method to quantify aristolochic acid DNA adducts in human tissues and applies it to hepatocellular carcinoma samples, finding a low prevalence of adducts.

This study uses DEER spectroscopy to show that a homo-dimeric protein complex is destabilized in human cells compared to solution, challenging excluded volume crowding theory.

This study shows an inactivated SARS-CoV-2 vaccine induces neutralizing antibodies and CTL responses in rhesus macaques, effectively preventing viral replication and lung inflammation.

The paper reports the cryo-EM structure of human NALCN with FAM155A, revealing interactions and ion-binding sites that inform Na+ permeation and disease mechanisms.

This paper describes a catalase-based therapeutic for COVID-19 that reduces oxidative stress and cytokine production in human and animal models without toxicity.

This study shows the SARS-CoV-2 envelope protein causes ARDS-like damage and identifies channel inhibitors as potential antiviral targets.

This study identifies PlsB as the key enzyme regulating membrane phospholipid synthesis in E. coli, showing its post-translational control coordinates membrane production with growth.

The paper reports cryo-EM structures of GPBAR-Gs complexes, revealing structural features of bile acid recognition, allosteric effects, and biased signaling.

This paper shows PIWIL1 promotes gastric cancer independently of piRNA by interacting with the NMD pathway.

The paper investigates the role of lamin B2 in nuclear mechanics and cancer cell invasion, finding that lamin B2 cooperates with lamin A/C to regulate nuclear deformability and migration efficacy.

This study evaluates the in vivo efficacy and PK/PD of KBP-7072, an aminomethylcycline antibiotic, in pneumonia and thigh infection models, showing significant dose-dependent reductions in CFUs and improved survival.

This meta-analysis compares the consistency of superb microvascular imaging and contrast-enhanced ultrasonography in detecting intraplaque neovascularization, finding a high Kappa index indicating good agreement.

This paper develops a transferable and interpretable deep learning model for MSI prediction from histopathology images, achieving high AUC scores in two cohorts.

This study shows that hexaploidization in wheat enhances genetic recombination of the ancestral diploid genome, increasing evolutionary potential and aiding wheat's global spread.

The paper shows that ITE, an AHR ligand, inhibits glioma cell migration and invasion by reducing MYH9 expression, which is critical for cell motility.

This study identifies an unconventional voltage-sensing mechanism in TRPV1 channels where outer pore acidic residues, not the S4 segment, mediate voltage sensitivity and activation.

The paper introduces a genetically encoded 1D 1H-NMR probe for studying conformational changes in large membrane protein complexes, demonstrating its effectiveness with minimal protein and time.

This study describes a method to expand pancreatic islet clusters in vitro using hormones and chemicals, resulting in functional islet-like structures with cell type markers.

This study compares the activation of MAPK and AKT signaling pathways by VEGFA165a and VEGFA165b in primary human retinal endothelial cells, finding stronger activation by VEGFA165a at lower doses.

This study identifies ferroptosis as a key developmental cell death mechanism in the rice blast fungus, showing its role in pathogenic growth and host invasion.

The paper tracks HIV-1 proviral clones over time in polyclonal populations, revealing stable, clone-specific expression patterns and clonal expansion dynamics independent of cell-type or metabolic factors.

This study examines changes in IL-10 expression in myocardial infarction and its association with macrophage activation and cardiomyocyte apoptosis over time.

The paper demonstrates efficient combined nitrogen, phosphorus, and chemical oxygen demand removal in a wastewater treatment system using anaerobic-aerobic cycling and nitritation-denitritation without exogenous chemicals.

This paper establishes a novel human HCC patient-derived xenograft model in immunocompetent mice, showing high tumor formation rates and preserved tumor characteristics.