F. Yang

This study identifies ATF3 as a key regulator that preserves skeletal muscle stem cell quiescence by preventing premature activation and maintaining genome stability.

This study shows that lumpy skin disease virus activates PERK and IRE1 pathways to support its replication, suggesting potential therapeutic targets for poxvirus infections.

This study identifies a novel endolysosomal trafficking pathway in Magnaporthe oryzae that facilitates effector secretion and host invasion via Rab7/Retromer/MoSnc1-mediated vesicle transport.

The paper identifies three deeply conserved super-enhancers in placental mammals that are essential for maintaining stem cell pluripotency.

The study shows that soil intake in mice increases gut microbial diversity and reduces serum IgE levels, suggesting potential prebiotic effects.

This study shows that collagen remodeling via MMP cleavage affects pancreatic cancer bioenergetics and outcome through DDR1 activation or degradation, with distinct impacts on tumor growth and survival.

This study shows that combining a photolabile Aβ ligand with LED or molecular light can reduce Aβ accumulation in mice, suggesting a new phototherapy approach for Alzheimer's disease.

This study shows that knocking out OsSWEET15 in rice reduces fertility by impairing embryo formation and seed-setting, with similar effects observed in OsSWEET11 mutants.

This study uses single-cell RNA-seq and TCR sequencing to identify tumor subtypes and cell-cell interactions in HSTCL, revealing disease progression and potential therapeutic targets.

This study identifies two distinct binding modes of RbFox's RNA Recognition Motif that contribute to its high sequence specificity and functional diversity.

This study shows that Serum Amyloid A (SAA) worsens acetaminophen-induced liver injury by damaging sinusoidal endothelial cells and increasing platelet aggregation.

The paper presents cryo-EM structures of yeast TRAPPII complex in apo and Ypt32-bound states, revealing its assembly mechanism and specific activation of Ypt31/Ypt32.

This study identifies fungal auxin as a quorum-sensing signal modulating rice blast disease severity through IAA biosynthesis and secretion.

This study shows that CD147 antibody inhibits SARS-CoV-2 infection and cytokine storm in variants by blocking viral entry and reducing inflammatory responses.

This study constructs and analyzes Stroke Symptom-Herb Networks (SSHNs) from historical TCM prescriptions to reveal their dynamic structure and evolutionary trends over 1700 years.

The paper screens cell-virus and cell-cell interactions across multiple species to identify potential hosts and co-evolution patterns of viruses including SARS-CoV-2.

DARTE-QM is a method using high-throughput sequencing to detect antibiotic resistance genes in environmental samples, demonstrating efficiency and scalability.

The paper constructs an orthologous gene coevolution network from 332 budding yeast species to explore eukaryotic cellular and genomic structure and function, revealing insights into gene connectivity and environmental fitness.

This study shows that strain gradients can drive directional cell migration in rat embryonic fibroblasts, distinct from durotaxis or haptotaxis.

This study shows that BPNT2 catalytic activity is essential for GAG sulfation, and lithium inhibits this process, affecting extracellular matrix composition and lithium's therapeutic effects.

This study identifies WDR5 as a reader of H3Q5ser, showing it binds to this modification and promotes transcription in neuroblastoma cells, suggesting a role in tumorigenesis.

This study identifies Tcfl5 as a testis-specific protein essential for male fertility, showing that heterozygous mice are infertile and exhibit abnormalities in spermatids and spermatozoa.

This study shows that feeding Ixodes pacificus larvae on lizards increases their likelihood of becoming infected with Borrelia burgdorferi compared to feeding on mice, and alters gene regulation.

This study analyzes the seasonal activities of the phyllosphere microbiome in switchgrass and miscanthus using metagenome and metatranscriptome sequencing to identify key microbial functions and their responses to environmental cues.

This study identifies a fungal oxylipin analogous to jasmonic acid as a morphogenetic signal that triggers pathogenic development in Magnaporthe oryzae by interacting with cyclic AMP and redox signaling.

The paper profiles single-cell transcriptomes of decidual macrophages in normal and recurrent spontaneous abortion patients, identifying distinct polarization states and potential therapeutic targets.

This study reports the crystal structures and biochemical characterization of SOQ1 lumenal domains, revealing their structural organization and potential regulatory mechanisms in suppressing qH.

This paper identifies the molecular mechanism by which SPIN*DOC inhibits Spindlin1's transcriptional coactivator activity through multivalent binding and competitive inhibition.

This study evaluates S-Trimer, a subunit vaccine candidate for COVID-19, showing it induces protective immunity in nonhuman primates with adjuvants.

The paper identifies Olfr109 as an olfactory receptor that detects insulin peptides in pancreatic β cells, modulating glucose metabolism and inflammation.