X. Zhao

This study uses iTRAQ proteomics to identify 20E and PLC inhibitor-regulated proteins in Apolygus lucorum, revealing shared and distinct DEPs and their involvement in metabolic and signaling pathways.

This study shows that a western-style diet impairs gut microbiota's ability to clear bacterial pathogens, leading to chronic inflammation and insulin resistance.

This paper develops a regional difference-based evaluation method for ecosystem service value (ESV) in Gansu Province, China, showing increased ESV from 2000 to 2015 with forest and urban ecosystems contributing most.

The paper identifies species-specific genetic differences in ACE2 that determine SARS-CoV-2 entry capability and shows that humanizing these residues in koala and mouse ACE2 enables viral entry.

This study identifies TaGS1.1 as critical for nitrogen assimilation and spike development in wheat by analyzing CRISPR-edited mutants and their growth responses under varying nitrogen conditions.

This study investigates L-arabinose's antifeedant effects on cotton bollworm caterpillars, showing it deters feeding, suppresses gustatory responses, and inhibits sucrase activity.

This study identifies placental hormones associated with pregnancy complications by analyzing the secretome of mouse placental cells and linking findings to human pregnancy outcomes.

The paper constructs a tyrosine kinase protein interaction map, revealing EGFR network oncogenesis in 19% of EGFR wild-type lung cancers, which is targetable with EGFR inhibitors.

The paper identifies 8 putative cell wall synthesis genes in Betula pendula using RNA-seq data and constructs a gene co-expression network.

This study identifies the molecular mechanism by which CheY-P controls rotational switching of the bacterial flagellar motor in Borrelia burgdorferi by interacting with FliM and remodeling FliG2.

The paper shows that Par-3 and dynein mediate polarized endosome movement during asymmetric division, leading to Notch signaling asymmetry in daughter cells.

The paper identifies two SNPs in SARS-CoV-2 genomes prevalent in North America, traces their origin to Europe, and suggests they could be targets for surveillance and treatment.

This paper identifies and characterizes Fnr paralogs in Paenibacillus polymyxa WLY78, showing their roles in regulating nitrogen fixation and anaerobic metabolism through gene expression changes.

This study shows obesity accelerates pancreatic cancer by altering the tumor microenvironment, with reversible effects through weight loss.

This study identifies redox and protein homeostasis as key factors in toxin-induced biliary atresia, showing that genetic modulation of these pathways affects cholangiocyte injury and suggesting potential therapeutic strategies.

This study expands the known diversity of magnetosome biogenesis in bacteria by analyzing new genomes and revealing an early evolutionary origin of magnetic nanoparticle formation.

This study identifies ACE2 orthologs from diverse species that can support SARS-CoV-2 entry, suggesting a broad host range for the virus.

This study shows that tumor-secreted extracellular vesicles suppress T-cell costimulation and that modifying these vesicles can enhance antitumor immune responses and improve immunotherapy effectiveness.

This study investigates how H-NS proteins evolved to sense environmental changes by comparing orthologs from different bacteria and using biophysical methods to reveal electrostatic interactions involved in adaptation.

The paper uses a HOXA9-mCherry reporter and CRISPR/Cas9 screens to identify USF1/USF2 as regulators of HOXA9 in MLLr leukemia, showing their role in leukemia cell proliferation.

This study investigates abortion rates and risk factors in dairy cows and sheep in Ili, China, identifying Brucella melitensis as the main pathogen and highlighting management factors contributing to reproductive issues.

This study examines ACE2 receptor usage by SARS-CoV-2 across 14 mammalian species, finding broad receptor activity and implications for zoonotic transmission and animal models.

This study shows that chemotherapy, not tumor-draining lymph nodes, determines immunotherapy response in secondary tumors using mouse models.

This study identifies LY6E as a host protein that restricts entry of human coronaviruses, including SARS-CoV-2, through a mechanism distinct from IFITM3.

The paper investigates how lectin-like intestinal defensin HD5 inhibits 2019-nCoV Spike protein binding to ACE2, showing a high-affinity interaction and protective effect in vitro.

This study identifies the COMPASS-like complex in M. oryzae and shows it regulates H3K4me3-mediated gene expression critical for fungal development and pathogenesis.

This paper shows that HCFC1 and HCFC1R1 deficiencies block HSV-1 infection by inhibiting nuclear translocation of HCFC1 and VP16, offering potential new therapeutic targets.

This paper introduces a NIR-II cell tracker for real-time monitoring of stem cell behavior in vivo, revealing differential responses to diseased environments and enabling long-term tracking beyond 30 days.

The paper analyzes 120 SARS-CoV-2 genomes to identify genetic subgroups, recombination events, and a unique spike protein insertion that may enhance infectivity.

Sleep deprivation rapidly increases serotonin 2A receptor expression in the mouse frontal cortex through the immediate early gene Egr3.