W. Li

This study investigates cadherin-6's role in thrombosis using murine models, finding that blocking or deleting cadherin-6 delays occlusion, while human platelets express it but murine do not.

This meta-analysis compares first-generation EGFR-TKI plus chemotherapy to EGFR-TKI alone in advanced EGFR-mutated NSCLC, finding improved ORR, PFS, and OS with the combination, but increased toxicity.

This paper reports the cryo-EM structure of the C9ORF72-SMCR8-WDR41 complex, revealing its role as a GAP for Rab8a and Rab11a.

The paper withdraws its manuscript due to the need for further experiments to validate conclusions.

This study shows cabozantinib enhances neutrophil-mediated delivery of nanoparticles to prostate tumors in mice, leading to higher NP accumulation in the tumor microenvironment.

This study shows that immunization with SARS-CoV-2 RBD elicits potent neutralizing antibodies without antibody-dependent enhancement in rodents.

The paper investigates how β-alanine and L-carnosine affect pork quality by modulating glycolysis and AMPK activity in porcine muscle.

The study shows that organic manure and rice straw residue increase soil microbial diversity and abundance in double-cropping paddy fields compared to chemical fertilizer alone or no fertilizer.

This study identifies an optimized mRNA UTR combination (NASAR) that significantly enhances SARS-CoV-2 antigen expression in vitro and in vivo.

This paper proposes a two-stage deep learning method for ECG denoising using U-net and DR-net models, showing improved performance over single-stage methods.

This study shows that destabilizing the HIV-1 capsid lattice leads to premature loss of the viral genome and integrase enzyme in infected cells.

The paper reports the structure of the ForT/PRPP complex and identifies residues critical for catalysis, proposing a mechanism for C-C bond formation in C-nucleotide antibiotic biosynthesis.

The paper identifies a high concentration of true S-cones in the ventral mouse retina, suggesting an adaptation for enhanced color detection in the upper visual field.

Click-ExM expands super-resolution imaging to all biomolecules by integrating click-labeling into expansion microscopy.

This paper introduces FucoID, a method to detect and isolate tumor-specific antigen-reactive T cells from tumor-infiltrating lymphocytes using fucosyl-biotinylation, revealing distinct gene features and functional capabilities.

This study shows that engineered HIV bnAb-expressing B cells can be expanded in vivo after vaccination, leading to durable bnAb memory and long-lived plasma cells.

This study identifies a functional ComRS competence pathway in Streptococcus sobrinus, revealing its genetic tractability and evolutionary implications.

This paper reports a human monoclonal antibody that neutralizes SARS-CoV-2 and SARS-CoV, targeting a shared epitope for potential prevention and treatment of COVID-19.

This study identifies B- and T-cell epitopes from SARS-CoV-2 surface glycoprotein using immune-informatics approaches, confirming their antigenicity and compatibility with HLA alleles for potential vaccine development.

This study shows that anethole dithiolethione improves liver fatty acid metabolism in hamsters on high-fat diets by altering fatty acid profiles and regulating key metabolic pathways.

The paper uses single-cell RNA sequencing to analyze stomatal lineage cell development in Arabidopsis, identifying new marker genes and transcriptional networks.

This paper introduces a high-throughput drug screening method called CEBIT that detects biomolecular interactions and enzyme inhibitors by using phase-separated compartments.

This study identifies new epigenetic and genetic biomarkers for esophageal cancer using cfDNA and combines SALP-seq with machine learning.

The paper identifies a molecular pathway involving cxcr4a/cxcl12b and pdgfb that drives arterial-specific accumulation of vascular smooth muscle cells during zebrafish development.

This study shows PRDM3 suppresses pancreatitis and pancreatic tumorigenesis by modulating inflammation and Kras-driven oncogenesis in acinar cells.

This study identifies three mechanisms by which class II HIV-1 integrase substitutions disrupt IN-RNA interactions, leading to virion maturation defects and premature viral genome degradation.

The paper identifies new RNA processing alterations and candidate target genes in glioblastoma cells after radiation exposure, suggesting potential strategies to improve treatment outcomes.

The paper shows that higher density cultures of hiPS-CMs increase Ik1 expression, leading to more stable electrophysiology and reduced spontaneous activity.

This study identifies RpvA, a LysR-type regulator in S. aureus, which controls persister formation and virulence by modulating metabolism and virulence gene expression.

This study identifies a new Asgard archaeal phylum, Gerdarchaeota, and shows their role in organic matter degradation in coastal sediments through genomic and transcriptomic analysis.