Y. Zhang

This paper introduces a core-shell microgel bioprinting method to create functional living materials with controlled microporosity and enhanced bioprocessing capabilities.

The paper identifies a tnd biosynthetic cluster in Aspergillus flavipes and characterizes a bifunctional diterpene synthase, leading to the discovery of talarodiene and its transformation into talaronoid C.

The paper identifies and characterizes an ABC transporter in Streptococcus pneumoniae that specifically transports ergothioneine, revealing its structure and conservation across bacterial species.

This study identifies the N-terminal domain (NTD) of p53 as the major binding site for Cyclophilin D, revealing dynamic electrostatic interactions and a minimal binding region for mPTP regulation.

The paper identifies maternal and embryonic signaling-driven differentiation of luminal epithelial cells in the mouse endometrium and shows conservation in humans.

This paper shows that teicoplanin inhibits SARS-CoV-2 cell entry by blocking cathepsin L proteolytic activity, effective against multiple variants with IC50 values of 2.038 M and 2.116 M.

The paper reconstructs the evolutionary history of therapy-related myeloid neoplasms using chemotherapy-associated mutational signatures and identifies distinct mutational patterns linked to different chemotherapies.

This study links HIV-associated gut dysbiosis to cytokine production capacity in ART-suppressed PLHIV, identifying specific microbial strains associated with immune markers.

The paper demonstrates that ubiquitination occurs in yeast mitochondrial matrix using components of the ubiquitin machinery, independent of cytosolic proteasome activity.

This study shows cystin deficiency reduces fibrocystin (FPC) levels in mouse renal cells, leading to proteome changes and cyst formation similar to ARPKD.

This study shows that the SARS-CoV-2 Spike protein disrupts lipid metabolism and autophagy, increasing lipotoxicity via ferroptosis, which can be mitigated by Nrf2 inhibition.

The paper uses organoid models to show that WNT2B promotes vascularization in pregnancies, linking trophoblast function to vascular development in both intrauterine and ectopic pregnancies.

The paper presents a single-cell transcriptomic atlas of Macaca fascicularis, identifying cell interactions and disease associations.

This study shows Piezo1 and 2 regulate centrosome integrity by modulating Ca2+ levels through mechanotransduction of cell intrinsic forces.

This study identifies bZIP25 and bZIP53 as transcription factors regulating pavement and trichome cell development in Arabidopsis thaliana using single-cell RNA-sequencing.

This study analyzes methicillin-resistant M. caseolyticus isolates from retail meat and GenBank, revealing geographic lineage distribution, antimicrobial resistance, virulence factors, and morphological differences.

The paper shows that waterbird community composition strongly predicts HPAI H5 occurrence in wild birds across different epidemics, with similar patterns observed for H5N8 and H5N1.

The paper identifies six monoclonal antibodies that broadly neutralize coronaviruses by targeting the conserved fusion peptide.

This study shows that separating kinase and phosphatase activities in the Bub complex is essential for proper mitosis, as merging these functions leads to mitotic defects.

The paper studies thermophoresis of various biomolecules in self-assembled matrices, showing enhanced thermodiffusion due to surrounding network effects.

This study identifies early urinary biomarkers in a rat model of multiple sclerosis and shows that early treatment with methylprednisolone reduces disease incidence.

This study compares antibody neutralization efficacy against SARS-CoV-2 Omicron sub-lineages BA.1, BA.1.1, BA.2, and BA.3, showing increased resistance and the benefit of vaccine boosters.

This study shows that knocking out the Angiotensin II Type 1a Receptor in rats reduces high-fat diet-induced obesity by enhancing adipose lipolysis through the cAMP/PKA pathway.

The paper shows redox regulation of mtLPD1 modulates photorespiration, TCA-cycle, and BCAA degradation in response to environmental changes.

This paper identifies two conserved regions on the Omicron RBD recognized by broadly neutralizing antibodies and develops an inhalable bispecific antibody with broad neutralization and therapeutic efficacy in mice.

This study identifies CIS as a regulator of GM-CSF signaling that controls macrophage polarization via the STAT5-IRF8 axis, influencing immune responses and allergic inflammation.

This study shows that nuclear import of Gdown1 modulates global transcription and enhances cellular stress tolerance.

The paper examines antibody responses to SARS-CoV-2 variants, finding convergent epitope specificities, V gene usage, and public B cell clones across different variants.

The paper identifies a C-terminal glutamine recognition mechanism by TRIM7 that targets viral proteins, revealing its role in antiviral defense against norovirus and SARS-CoV-2.

The paper derives an analytical expression for condensate exchange timescales and shows interface resistance can arise from molecular bouncing at the droplet interface.