G. Li

This study characterizes 52 patient-derived glioma cell lines with whole-genome sequencing, RNA-seq, and drug response screening, identifying three subtypes and their drug sensitivities and tumorigenic potential.

This paper describes a CURE course focused on fungal effectors that enhances undergraduate education through authentic research and real-world problem-solving.

The paper describes a new species of vampire squid, Vampyroteuthis pseudoinfernalis, distinguished by morphological and genetic differences from the known species Vampyroteuthis infernalis.

The paper introduces TAMiT, an automated tool for tracking fluorescent microtubules in yeast cells, showing it reliably detects and measures microtubule dynamics even at low signal-to-noise ratios.

This study redefines hematopoietic progenitor cells and reformulates the hematopoiesis hierarchy using a transcriptional atlas, identifying key transcription factors and distinct lineage commitment processes.

The paper identifies a CRISPR trimmer-integrase that processes DNA for integration in the absence of Cas4, using cryo-EM structures to show its mechanism.

This study develops a sessile drop chip to create 3D spheroids of fibroblasts and macrophages, showing that M2 macrophages enhance fibroblast proliferation and differentiation in a wound-healing model.

The paper sequences and assembles the nuclear and mitochondrial genomes of Bipolaris sorokiniana strain LK93 to improve understanding of its interaction with wheat.

This study shows that the ESCRT pathway and MVBs are essential for trap formation in the nematode-trapping fungus Arthrobotrys oligospora in response to ammonia.

This study identifies MADS31 as a transcriptional repressor that maintains nucellar identity in barley ovules by repressing seed-specific genes like NRPD4b, ensuring proper female germline development.

This study shows that combining mesenchymal stromal cells and alpha-1 antitrypsin significantly improves inflammation modulation and resolution in vitro and in a mouse model.

This study shows light-activated molecular machines can remotely stimulate intercellular calcium waves, controlling muscle contraction in vitro and animal behavior in vivo.

This study investigates the excited-state dynamics of the all-trans protonated retinal Schiff base in CRABPII-based rhodopsin mimics using transient absorption and fluorescence spectroscopy, revealing differences in dynamics across mutants and potential applications in bioimaging.

This study shows that Gaq-PKD/PKCμ regulates IκB transcription to limit NF-κB-mediated inflammation, essential for successful early pregnancy.

This paper presents a subunit vaccine, PF-D-Trimer, derived from the Delta spike protein, showing robust immunogenicity and cross-reactive neutralizing antibodies against multiple SARS-CoV-2 variants.

This study sequenced the genome of water wisteria, revealing genes and pathways involved in its environmental adaptation and leaf shape changes.

This study investigates how cold-chain conditions and disinfection methods affect SARS-CoV-2 stability, finding that low temperature and seawater increase viral survival while LED light and airflow reduce it.

This paper introduces a self-blinking DNA probe for 3D superresolution imaging of native chromatin in live cells, revealing chromatin organization and decompaction dynamics.

The paper identifies incomplete lineage sorting in Sulfitobacter, a marine bacterium, showing rapid speciation driven by ancestral polymorphism retention rather than adaptive selection.

This study assembled the chromosome-level genome of Rorippa aquatica to investigate its allotetraploid origin and the molecular mechanisms of heterophylly under submergence.

This study shows that CTRP3 reduces intestinal inflammation in colitis models and IBD patients by modulating SIRT1/NF-κB signaling to suppress pro-inflammatory cytokines.

This study identifies CiS40-11 and its orthologs AtS40-5 and AtS40-6 as regulators of leaf senescence that promote cytokinin synthesis by inhibiting MYB2 expression.

This study compares the effects of immunomodulatory BT peptide and antibiotics on cecal microbiota in broilers challenged with Clostridium perfringens, finding differences in microbial composition and function.

This study shows that blocking the sympathetic nervous system reduces fasting-induced liver fat accumulation by suppressing CD36 upregulation.

This paper identifies a novel intergeneric recombinant geminivirus as the cause of soybean stay-green disease, showing it induces symptoms and can be detected in seed coats but not seeds.

This study identifies alkaloids and related intermediates in Dendrobium officinale using SPE-HPLC-LTQ-Orbitrap and database alignment.

This study uses single-nuclei transcriptomics to analyze dog hippocampus cell types and identifies convergence between differentially expressed genes and putative positively selected genes related to nervous system development.

This study shows that palatal morphology in early salamanders reflects ecological preferences and life history strategies, with significant evolutionary changes before the Middle Jurassic.

The paper determines the asymmetric homodimer structure of mouse pendrin using cryo-EM, revealing its electroneutral anion exchange mechanism and pathogenetic mutation properties.

This study presents three amphioxus reference genomes, revealing insights into chordate gene and chromosome evolution, including WGDs, chromatin architecture, and sex chromosome dynamics.