S. Wang

This study uses cryo-EM to reveal the mechanism of TRiC/CCT ring assembly in yeast, showing subunit-specific roles and ATP-driven assembly dynamics.

The paper develops fluorescent probes to visualize SARM1 activation and identifies a nisoldipine derivative as a SARM1 inhibitor that protects axons from degeneration.

This study identifies OsNLP3 as a key regulator of nitrogen use efficiency and grain yield in rice under nitrate-sufficient conditions.

The study examines how opposing genetic dominance in a color gene block affects plumage signals and territorial behavior in hybrid songbirds, linking genetic variation to fitness outcomes.

The paper identifies that CXCL12 at the blood-brain barrier attracts NK cells and ILCs to ischemic brain lesions, improving outcomes after stroke.

This study develops a multi-epitope chimeric antigen (MECU) that generates a broadly reactive antibody response against H. pylori and reduces stomach colonization in mice.

The paper identifies and evaluates strong constitutive promoters in Listeria monocytogenes to enhance foreign antigen expression, finding P18 as the most effective.

This study investigates the structure and function of SslE in E. coli biofilm maturation, showing its role in aggregate formation and exopolysaccharide distribution under acidic conditions.

This study shows that in vitro evolution of SARS-CoV-2 under remdesivir selects for resistant mutations, but these mutations do not spread widely in global variants.

This study investigates the effects of carbon, nitrogen, phosphorus, and potassium on flowering and fruiting of Glycyrrhiza uralensis, finding that higher levels of C, P, and K benefit flower bud differentiation, while excessive N is detrimental, and optimal N and K levels at the filling stage improve seed setting and filling.

This study identifies PDGFRβ as a host factor required for JEV infection and shows that imatinib can protect against JEV by reducing viral load and histopathology.

This study shows that PEBP4 interacts with TYLCV CP to regulate apoptosis and autophagy in whiteflies, balancing virus loading and immune response.

This paper demonstrates that SHIVs with bulky aromatic amino acid substitutions at Env375 replicate efficiently in rhesus macaques and can be used for preclinical HIV vaccine testing.

This study compares the performance of Autof MS 1000 and Bruker MALDI-TOF MS systems in identifying Nocardia species using clinical isolates and sequence analysis as a reference.

This study shows IRGM/Irgm1 worsens atherosclerosis by causing macrophage apoptosis via the MAPK pathway, increasing plaque vulnerability and risk of rupture.

This study shows that IFNa-based combinations effectively inhibit SARS-CoV-2 infection in vitro and in vivo, with synergistic effects against other viruses.

This study examines how different coral compartments shape microbial evolution by analyzing genome sequences of Rhodobacteraceae in mucus and skeleton, identifying genetic adaptations to compartment-specific environments.

The paper examines HDP gene expression and tissue distribution in different chicken breeds, finding correlations between body weight, age, and HDP expression in immune organs and intestine.

This study shows that TIR signaling is essential for enhancing plant defense during pattern-triggered immunity by activating defense genes and increasing resistance to pathogens.

This study determines the cryo-EM structures of Cas12f to elucidate its dimerization-dependent mechanism for DNA cleavage and substrate recognition.

This paper develops a subunit vaccine against SARS-CoV-2 that induces sterilizing immunity in hamsters, with high neutralizing antibody titers and protection against infection and symptoms.

The paper introduces REPOST, a framework predicting potential virus hosts by analyzing receptor orthologs, achieving 95.74% accuracy for SARS-CoV-2.

This study finds that the rs3842753 C allele is associated with higher INS mRNA and ER stress in beta cells, suggesting a link between genetic variation and beta cell dysfunction in type 1 diabetes.

This study shows SARS-CoV-2 Spike protein damages endothelial cells by reducing ACE2 expression and impairing mitochondrial function, leading to vascular inflammation.

This study shows that A-to-I RNA editing in Xanthomonas oryzae enhances iron uptake by modifying the xfeA gene, improving bacterial competitiveness in iron-limited environments.

The paper evaluates a PKC inhibitor in a T2D rat model, finding it halts renal decline indirectly via reduced hyperphagia and directly lowers adiposity.

This paper introduces 2bRAD-M, a low-cost metagenome-sequencing method that enables species-level microbial profiling of low-biomass and degraded samples with high accuracy.

This paper describes a multitope protein-peptide vaccine candidate, UB-612, that is immunogenic and prevents lung infection in animal models, with ongoing clinical trials.

This study identifies Cwl0971 as a peptidoglycan hydrolase in C. difficile that affects autolysis, toxin release, sporulation, and pathogenicity.