X. Liu

This study identifies a viral protein translation mechanism involving mitochondrial machinery and highlights mitochondria as a target for antiviral drug development.

This study shows that influenza A virus pre-infection increases SARS-CoV-2 infectivity in multiple cell types and worsens lung damage in mice.

The paper identifies a peroxidase inhibitor, 6D1, that enhances kanamycin activity against carbapenem-resistant bacteria.

This paper develops flexible, transparent silver nanowire microelectrodes for multifunctional biointerfacing, showing high optical transparency, low impedance, and good biocompatibility in heart monitoring.

This study identifies KIM1 as a potential receptor for SARS-CoV-2 in the kidney, showing it binds RBD with similar affinity to ACE2 and facilitates viral entry.

This study shows that inhibiting PLK1 promotes reactivation of KSHV and EBV in B-cell lymphomas, leading to cell death, and identifies PLK1 as a potential therapeutic target for HIV-positive patients.

This study compares the temporal transcriptomes of two Verticillium dahliae strains to identify pectin degradation genes linked to pathogenicity in Upland cotton.

This study identifies CDF-1 and SUR-7 as regulators of lipid metabolism in C. elegans, linking zinc homeostasis to lipid accumulation via the SREBP-SCD pathway.

The paper introduces implantable photonic neural probes that enable light-sheet fluorescence imaging in brain tissues without additional micro-optic components.

This study shows that deleting Slc26a9 in parietal cells of mice leads to spontaneous gastric cancer and identifies molecular mechanisms involved in tumor progression.

This study uses single-cell RNA-seq to analyze stromal vascular fraction cells in cancer-related lymphedema, identifying lineage-specific changes and potential therapeutic targets.

The paper identifies a suboptimal-health gum state (SoH) during experimental gingivitis, characterized by microbiome and metabolite changes similar to periodontitis.

This study investigates the electrophilicity of saturated oxo-fatty acids and finds that mono-saturation retains electrophilicity, while double saturation abolishes it, implicating PTGR1 in their metabolism.

This study shows that IgT is the main immunoglobulin induced in trout skin mucosa during bacterial infection, with SALT serving as a key inductive site.

The paper reclassifies Catabacter hongkongensis into the genus Christensenella based on whole-genome analysis showing it belongs to the Christensenella clade.

This study investigates the role of AAA4 ATPase in cytoplasmic dynein's mechanochemical cycle using single-molecule techniques, showing its critical role in enabling motion through interactions with AAA1 and AAA3.

This study identifies a novel mechanism where Src-mediated phosphorylation of Rpt2-Y439 regulates proteasome function at cellular membranes, impacting cancer therapy response.

This study identifies humanized single domain antibodies that neutralize SARS-CoV-2 by targeting the spike receptor binding domain, showing improved activity when fused with the Fc region.

The paper develops a phospholipid-mimicking LRH-1 agonist that shows in vivo efficacy in a colitis model by improving binding affinity and transcriptional activity.

This study analyzes plasmablast-derived antibodies in three COVID-19 patients, identifying neutralizing antibodies and cross-reactivity with other betacoronaviruses.

This paper identifies a novel allele of the chromogen gene C from wild rice that regulates anthocyanin biosynthesis differently in indica and japonica subspecies.

This paper introduces a variational inference method for coalHMMs that learns evolutionary parameters and infers local genealogies with comparable accuracy to existing methods, using simulated data.

This study develops a cell-based chimeric vaccine against SARS-CoV-2 that induces strong T cell immunity and neutralizing antibodies without toxicity.

The paper studies how IRE1 and PERK signaling branches coordinate during ER stress, finding mutual inhibition and differential sensitivity regulated by p58IPK.

The paper develops new fluorogenic probes for live-cell and super-resolution microscopy with minimal label size and efficient quenching.

This study examines how maize plants respond to drought, flooding, and rewatering, finding that photosynthetic traits recover after rewatering, with resilience depending on drought severity and plant growth stage.

The paper identifies a zinc metabolic defect in alveolar progenitor cells in IPF and aged mice, linked to impaired renewal and fibrosis through ZIP8 downregulation.

This study identifies metabolic defects in alveolar progenitor cells during aging and lung injury that impair their renewal capacity.

This paper shows that PBP4 localizes at midcell during septal PG synthesis in E. coli and is important for the timing of divisome assembly.

This study compares the gut DNA and RNA viromes of Chinese residents and Pakistani visitors, finding ethnic origin significantly influences virome composition and diversity.